Explore top 2025 5 Star Hotels in Uptown
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Top Uptown 5 Star hotels

The Crawford Hotel
1701 Wynkoop Street, Denver, CO
Fully refundableReserve now, pay when you stay
$373 nightly
The price is $432 total per night from Oct 28 to Oct 29
$432 total
Oct 28 - Oct 29
Total with taxes and fees
A full-service spa, 4 restaurants, and a 24-hour gym are all featured at this smoke-free hotel. Enjoy a meal in one of the 3 coffee shops/cafes and perks like ...
9.2/10 Wonderful! (1,002 reviews)
"Clean room, staff is friendly"
Reviewed on Oct 5, 2025

Four Seasons Hotel Denver
1111 14th St, Denver, CO
Fully refundableReserve now, pay when you stay
$625 nightly
The price is $723 total per night from Nov 1 to Nov 2
$723 total
Nov 1 - Nov 2
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and babysitting. ...
9.4/10 Exceptional! (962 reviews)
"Great staycation! Thx!"
Reviewed on Oct 1, 2025

The Ritz-Carlton, Denver
1881 Curtis St., Denver, CO
Fully refundableReserve now, pay when you stay
$422 nightly
The price is $488 total per night from Oct 29 to Oct 30
$488 total
Oct 29 - Oct 30
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center, ...
9/10 Wonderful! (864 reviews)
"great hospitality"
Reviewed on Aug 31, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Uptown hotel reviews by fellow wanderers

Sonesta Denver Downtown
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"The stay was great. Very nice hotel and perfect placement! "
A verified traveler stayed at Sonesta Denver Downtown
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