Explore top 2025 5 Star Hotels in Palo Alto

Name: Clement Palo Alto – All-Inclusive Urban Resort
Price range: $882 total
Rating: 9.8

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Top Palo Alto 5 Star hotels

Shashi Hotel Mountain View Palo Alto

1625 N Shoreline Blvd, Mountain View, CA

Fully refundableReserve now, pay when you stay

$126 nightly

$139 total

Nov 22 - Nov 23

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

9.2/10 Wonderful! (1,131 reviews)

The rooms are very modern clean and the bed is very comfortable the hotel overall is stunning

Reviewed on Nov 11, 2025

Four Seasons Hotel Silicon Valley at East Palo Alto

2050 University Ave, East Palo Alto, Palo Alto, CA

Fully refundableReserve now, pay when you stay

$360 nightly

$409 total

Dec 14 - Dec 15

Total with taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the express check-in, ...

9.2/10 Wonderful! (660 reviews)

Nice one

Reviewed on Sep 16, 2025

Rosewood Sand Hill

2825 Sand Hill Road, Menlo Park, CA

Fully refundableReserve now, pay when you stay

$823 nightly

$929 total

Dec 13 - Dec 14

Total with taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Enjoy the gym and perks like free WiFi and a free area shuttle. ...

9.4/10 Exceptional! (273 reviews)

Really great hotel and my go to place for anything in Palo Alto

Reviewed on Oct 24, 2025

Nobu Hotel Palo Alto

180 Hamilton Ave, Palo Alto, CA

Fully refundableReserve now, pay when you stay

$425 nightly

$492 total

Nov 21 - Nov 22

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and valet parking. A terrace ...

9/10 Wonderful! (429 reviews)

Loved the clean room and a very friendly staff.

Reviewed on Nov 9, 2025

Clement Palo Alto – All-Inclusive Urban Resort

711 El Camino Real, Palo Alto, CA

Fully refundableReserve now, pay when you stay

$763 nightly

$882 total

Nov 14 - Nov 15

Total with taxes and fees

A restaurant and a gym are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...

9.8/10 Exceptional! (109 reviews)

Great hotel!!

Reviewed on Oct 17, 2025

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Palo Alto Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Palo Alto to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Palo Alto 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Palo Alto before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.