Explore top 2026 5 Star Hotels in Downtown Buffalo

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Top Downtown Buffalo 5 Star hotels

Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel

5 out of 5
210 Franklin St Buffalo NY
Fully refundable
$208 nightly
The price is $243 total per night from Jan 1 to Jan 2
$243 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
This smoke-free hotel features a full-service spa, hot springs, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free ...
9.2/10 Wonderful! (1,004 reviews)
Friendly staff and urban spa is great!

Reviewed on Dec 26, 2025

Opens in a new windowCurtiss Hotel, an Ascend Collection Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Downtown Buffalo hotel reviews by fellow wanderers

Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

5 out of 5
Posted 22 hours ago
Travelocity Verified Review
"The furniture is a little outdated, but other than that, it’s a great hotel. "
A verified traveler stayed at Hyatt Regency Buffalo / Hotel and Conference Center
Hyatt Regency Buffalo / Hotel and Conference Center

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