Explore 11 Luxury Hotels in Downtown Buffalo

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Best Luxury Hotels in Downtown Buffalo

Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel

210 Franklin St Buffalo NY
Fully refundable
$246 nightly
The price is $287 total per night from May 17 to May 18
$287 total
May 17 - May 18
Total with taxes and fees
This smoke-free hotel features a full-service spa, hot springs, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free ...
9.4/10 Exceptional! (1,001 reviews)
We loved the hot spring pool!

Reviewed on May 14, 2026

Opens in a new windowCurtiss Hotel, an Ascend Collection Hotel
The Mansion On Delaware Ave

The Mansion On Delaware Ave

414 Delaware Ave Buffalo NY
Fully refundableReserve now, pay when you stay
$234 nightly
The price is $269 total per night from May 19 to May 20
$269 total
May 19 - May 20
Total with taxes and fees
This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
9.4/10 Exceptional! (1,003 reviews)
Our 4th floor room was spacious and full of light with a lovely gas fireplace and street view. The bathroom was huge and the shower and amenities were great. Free glass of wine/beer is a nice touch. Breakfast was fine. It’s a lovely place but unfortunately our stay was not restful and it made us ...

Reviewed on May 8, 2026

Opens in a new windowThe Mansion On Delaware Ave
Lofts on Pearl Trademark Collection by Wyndham

Lofts on Pearl Trademark Collection by Wyndham

92 Pearl Street Buffalo NY
This apartment features 2 restaurants, free WiFi in public areas, and a snack bar/deli. Dry cleaning, luggage storage, and free newspapers are also on ...
9.2/10 Wonderful! (520 reviews)
Great location
Very easy and fast check in. Property manager managed to find ways to connect with me after unable to contact Expedia that our original property is closed on Sunday and we have to move to another property. The info provided was accurate. The location is really good. Close to city and easy access ...

Reviewed on Oct 14, 2020

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Opens in a new windowLofts on Pearl Trademark Collection by Wyndham
Courtyard Buffalo Downtown / Canalside

Courtyard Buffalo Downtown / Canalside

One Canalside, 125 Main Street Buffalo NY
Fully refundableReserve now, pay when you stay
$190 nightly
The price is $222 total per night from May 25 to May 26
$222 total
May 25 - May 26
Total with taxes and fees
This hotel features 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9/10 Wonderful! (1,001 reviews)
Helpful staff, clean room, beautiful hotel & steps away from KeyBank Center - perfect location! We used the easy access overflow parking. It's been years since I've stayed here & I can't wait to come back!

Reviewed on May 12, 2026

Opens in a new windowCourtyard Buffalo Downtown / Canalside
Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown

220 Delaware Ave Buffalo NY
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $194 total per night from May 26 to May 27
$194 total
May 26 - May 27
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an indoor pool, and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and WiFi in public areas. ...
8.8/10 Excellent! (1,005 reviews)
Good location, gated parking. Staff was nice. Room we stayed in is just about ready for a refresh, but it was clean and nice.

Reviewed on May 11, 2026

Opens in a new windowHampton Inn & Suites Buffalo Downtown
Hotel at the Lafayette Trademark Collection by Wyndham

Hotel at the Lafayette Trademark Collection by Wyndham

391 Washington St Buffalo NY
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $163 total per night from May 25 to May 26
$163 total
May 25 - May 26
Total with taxes and fees
A 24-hour gym is featured at this hotel, along with a coffee shop and free WiFi in public areas. A lobby fireplace, luggage storage, and wedding services are ...
8.4/10 Very Good! (1,001 reviews)
This was a very unique hotel! Loved the old time look and decor! Staff was friendly, our room was not ready at the check in hour, we had to wait another 40 minutes before getting into the room. Our bed was not overly comfortable for us. They supposedly serve coffee till 2 pm, but after that they ...

Reviewed on May 8, 2026

Opens in a new windowHotel at the Lafayette Trademark Collection by Wyndham
Embassy Suites Buffalo

Embassy Suites Buffalo

200 Delaware Avenue Buffalo NY
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $191 total per night from May 24 to May 25
$191 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.2/10 Very Good! (1,000 reviews)
Great hotel close to everywhere I needed to be. Staff was super friendly. Room was comfy. Room service from the Italian spot in the hotel was delicious. Will be my go to for future Buffalo trips.

Reviewed on May 12, 2026

Opens in a new windowEmbassy Suites Buffalo
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

Two Fountain Plaza Buffalo NY
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $167 total per night from May 26 to May 27
$167 total
May 26 - May 27
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
8.2/10 Very Good! (1,764 reviews)
I will always choose the Hyatt if and when I can. The rooms are always very clean and the staff is great. I just wish they had continental breakfast.

Reviewed on May 13, 2026

Opens in a new windowHyatt Regency Buffalo / Hotel and Conference Center
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Downtown Buffalo

Buffalo Harmony House

Buffalo Harmony House

70 Wadsworth Street Buffalo NY
$257 nightly
The price is $294 total per night from May 17 to May 18
$294 total
May 17 - May 18
Total with taxes and fees
10/10 Exceptional! (49 reviews)

5 star hotels in Downtown Buffalo

Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel

210 Franklin St Buffalo NY
$246 nightly
The price is $287 total per night from May 17 to May 18
$287 total
May 17 - May 18
Total with taxes and fees
9.4/10 Exceptional! (1,001 reviews)

Downtown Buffalo Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Downtown Buffalo luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Downtown Buffalo to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Downtown Buffalo will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Downtown Buffalo, and plan your next opulent escape.


Downtown Buffalo hotels essential information

Accommodation
1,206 hotels
Lowest Price
$163
Highest Price
$422
Popular hotels
Curtiss Hotel, an Ascend Collection Hotel, Embassy Suites Buffalo, Hotel at the Lafayette Trademark Collection by Wyndham, The Mansion On Delaware Ave, Hampton Inn & Suites Buffalo Downtown, Courtyard Buffalo Downtown / Canalside, Hyatt Regency Buffalo / Hotel and Conference Center, Lofts on Pearl Trademark Collection by Wyndham

Popular Luxury Stays in Downtown Buffalo

5 Stars Luxury stays in Downtown Buffalo
Hotels 5 Stars
Hotels 5 Stars
Luxury stays in Downtown Buffalo with spa
Hotels with Spa
Hotels with Spa

Recent Downtown Buffalo Hotel Reviews By Fellow Wanderers

Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel

5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"We loved the hot spring pool!"
A verified traveler stayed at Curtiss Hotel, an Ascend Collection Hotel
Curtiss Hotel, an Ascend Collection Hotel

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