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Top hotels in Grand Isle

Luxury Gulf-Front Retreat. Heated Pool, Pet-Friendly. November Discounts
We had one of our best family Christmas and stays at the beach! We arrived at the spotless house which is light, bright and inviting with a perfect layout of being able to hang out in the open concept kitchen, dining, living area, playing ping pong, corn hole or shuffle board or just reading a book ...
Reviewed on Jan 5, 2026

Luxury Home w/ Golf Cart, Heated Pool, Bikes, Beach Equipment, & Pet Friendly!
Chelsea was very welcoming and wanted to make sure that we had the best time. When I contacted her about a few issues that were definitely our fault, she was very understanding. The home was spotless. The beds were very comfortable and there were plenty of towels! There were many nice amenities… ...
Reviewed on Jan 3, 2026

Mexico Beach Condo steps from the beach! ~Snowbird Rates Available~
Wonderful
Reviewed on Jan 21, 2026

Candlewood Suites Panama City Tyndall AFB by IHG
Room was very clean and staff very friendly.
Reviewed on Jan 27, 2026

The Port Inn and Cottages, an Ascend Collection Hotel
Exactly what I was looking for a quick overnight business stay. Inn was very nice and clean. Room was very nice and clean, very quiet on the North side of the corridor. Breakfast was very good and perfect amount of options for complementary.
Reviewed on Feb 11, 2026

MainStay Suites Port Saint Joe South
Staff was great. Room was very nice. Overall a very good stay
Reviewed on Jan 28, 2026

Comfort Suites
Staff was friendly. Room was clean and great breakfast variety.
Reviewed on Dec 16, 2025

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
Everything was wonderful and the staff was great
Reviewed on Feb 12, 2026

Unique waterfront home with wraparound deck and private grill - free WiFi
Wonderful location, unique home. Perfect for a peaceful and relaxing getaway!
Reviewed on Sep 12, 2025
Grand Isle Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Grand Isle area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Grand Isle to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Grand Isle are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Grand Isle hotel reviews by fellow wanderers

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
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