Find a Hotel in East Seneca

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top hotels in East Seneca

Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

3 out of 5
125 High St Buffalo NY
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $154 total per night from Mar 22 to Mar 23
$154 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport ...
Team went out of there way and we will be back when we visit Buffalo

Reviewed on Mar 14, 2026

Opens in a new windowWyndham Garden Buffalo Downtown
Tru by Hilton Williamsville Buffalo Airport

Tru by Hilton Williamsville Buffalo Airport

2.5 out of 5
48 Freeman Road Buffalo NY
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $120 total per night from Mar 22 to Mar 23
$120 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features an indoor pool and a gym. Relax with a drink at the bar/lounge and enjoy free perks like self-serve breakfast and free self parking. A business ...
All the staff were wonderful, great free breakfast, great pool area, close to restaurants and shopping!

Reviewed on Mar 14, 2026

Opens in a new windowTru by Hilton Williamsville Buffalo Airport
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 out of 5
601 Main St Buffalo NY
Fully refundable
$104 nightly
The price is $121 total per night from Apr 5 to Apr 6
$121 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the business center. Enjoy ...
Was great

Reviewed on Mar 12, 2026

Opens in a new windowHoliday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza Buffalo NY
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $188 total per night from Mar 29 to Mar 30
$188 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Very clean. Staff was super helpful.

Reviewed on Mar 14, 2026

Opens in a new windowHyatt Regency Buffalo / Hotel and Conference Center
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

2.5 out of 5
131 Buell Ave Buffalo NY
Fully refundable
$110 nightly
The price is $125 total per night from Apr 5 to Apr 6
$125 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Na

Reviewed on Mar 14, 2026

Opens in a new windowHoliday Inn Express Hotel & Suites Buffalo-Airport by IHG
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $108 total per night from Mar 29 to Mar 30
$108 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Bed bug bites! Covered in bites during a stay.

Reviewed on Mar 15, 2026

Opens in a new windowBuffalo Airport Hotel
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
Fully refundable
$76 nightly
The price is $86 total per night from Mar 29 to Mar 30
$86 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
A

Reviewed on Mar 15, 2026

Opens in a new windowSleep Inn & Suites Buffalo Airport
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $108 total per night from Apr 2 to Apr 3
$108 total
Apr 2 - Apr 3
Total with taxes and fees
This hotel features a 24-hour gym and a sauna. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
Staff were amazing and very friendly. There was one microwave we could use in a different hall that didn't work when we tried. The wifi was spotty. The room was clean and we were able to get extra towels when we asked. It is definitely a unique place and the garden was really cool.

Reviewed on Mar 14, 2026

Opens in a new windowGarden Place Hotel
M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave Buffalo NY
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $96 total per night from Mar 29 to Mar 30
$96 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport ...
Unfortunately this hotel is rapidly declining. 4 years ago when it was the Millennium it was great. I came back recently, traveling for business regularly. It's gone downhill in a matter of months. Staff at the desk (besides 2 ladies) are completely incompetent. This is not rocket science - check ...

Reviewed on Mar 15, 2026

Opens in a new windowM Hotel Buffalo
Don't see what you're looking for?
See all available properties in East Seneca
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

East Seneca Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on East Seneca area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near East Seneca to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near East Seneca are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent East Seneca hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity