Book Hotels in Upstate South Carolina, SC

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Top Upstate South Carolina hotels

Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson SC
Free WiFi in public areas is available at this cottage.
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Opens in a new windowWooded Cottage - 3 Mi to Clemson University
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$276 nightly
The price is $304 total per night from Nov 30 to Dec 1
$304 total
Nov 30 - Dec 1
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
great service

Reviewed on Nov 16, 2025

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $94 total per night from Nov 30 to Dec 1
$94 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Freindly staff nice and clean

Reviewed on Nov 24, 2025

Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $101 total per night from Dec 7 to Dec 8
$101 total
Dec 7 - Dec 8
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Love the corner room. So large

Reviewed on Nov 27, 2025

Opens in a new windowEmbassy Suites Greenville Golf Resort & Conference Center
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
Fully refundable
$83 nightly
The price is $92 total per night from Dec 22 to Dec 23
$92 total
Dec 22 - Dec 23
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Yes

Reviewed on Nov 18, 2025

Opens in a new windowCrowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

3 out of 5
11 Ketron Court Greenville SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Nov 30 to Dec 1
$101 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center and ...
I was very relieved when i walked in the lobby. It was clean and the staff was very helpful and polite. I even stayed a second night!

Reviewed on Nov 15, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $110 total per night from Dec 14 to Dec 15
$110 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
Staff was super friendly and helpful, property was cleaned and on the daily

Reviewed on Nov 22, 2025

Opens in a new windowHilton Greenville
ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

2 out of 5
490 W Blackstock Road Spartanburg SC
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $81 total per night from Nov 30 to Dec 1
$81 total
Nov 30 - Dec 1
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
Yes, it was good

Reviewed on Nov 20, 2025

Opens in a new windowECHO Suites Extended Stay by Wyndham Spartanburg
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

3 out of 5
65 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $79 total per night from Nov 30 to Dec 1
$79 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. ...
The refrigerator wasn't working right

Reviewed on Nov 23, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Greenville Haywood
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Upstate South Carolina hotels

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

128 Interstate Blvd Anderson SC
$60 nightly
The price is $66 total per night from Dec 1 to Dec 2
$66 total
Dec 1 - Dec 2
Total with taxes and fees
7/10 Good! (838 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Upstate South Carolina hotel reviews by fellow wanderers

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Beautiful place, awesome staff!"
A verified traveler stayed at Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference Center

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