Book Hotels in Upstate South Carolina, SC

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Top Upstate South Carolina hotels

SpringHill Suites by Marriott Greenville Downtown

SpringHill Suites by Marriott Greenville Downtown

2.5 out of 5
200 East Washington Street, Greenville, SC
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $127 total per night from Aug 3 to Aug 4
$127 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
Awesome
"Absolutely awesome staying. Hotel was beautiful and convenient. Staff was friendly and helpful. We stay there again in October"

Reviewed on Jul 9, 2025

SpringHill Suites by Marriott Greenville Downtown
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd, Greenville, SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Jul 27 to Jul 28
$93 total
Jul 27 - Jul 28
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Decent hotel with excellent service. Upon arrival, my toilet was working poorly, so I asked for a plunger. Turns out it was just the way the toilet worked...slowly. The sink also drains slowly, so I suspect the plumbing needs work. The design of the hotel has only one elevator on each side of the ..."

Reviewed on Jul 9, 2025

Best Western Plus Greenville I-385 Inn & Suites
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $172 total per night from Jul 13 to Jul 14
$172 total
Jul 13 - Jul 14
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"We chose Hyatt Regency because of its proximity to Bon Secours arena. What we also enjoyed was the food, the cleanliness of our room, the comfort of the bed, quiet, and a very friendly and helpful staff."

Reviewed on Jul 10, 2025

Hyatt Regency Greenville
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
Fully refundable
$95 nightly
The price is $105 total per night from Aug 3 to Aug 4
$105 total
Aug 3 - Aug 4
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Our first Greenville, SC experience
"My family and I enjoyed our stay. The hotel location was perfect for our needs. Easy access to the highway and getting to downtown Greenvillewas a plus. The hotel itself was comfortable. No noise complaints or smoking in the hotel and the environment was calm and friendly. I found the rear parking ..."

Reviewed on Jul 1, 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport

2.5 out of 5
205 Entertainment Blvd, Greenville, SC
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $72 total per night from Jul 13 to Jul 14
$72 total
Jul 13 - Jul 14
Total includes taxes and fees
Free WiFi in public areas is provided and the front desk is staffed around-the-clock. Free self parking and luggage storage are also offered on site.
"."

Reviewed on Jul 10, 2025

Woodspring Suites Greenville Airport
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $126 total per night from Jul 20 to Jul 21
$126 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
"I like that fact you can’t get anywhere in the building unless you have a key card"

Reviewed on Jul 5, 2025

Hilton Greenville
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road, Greenville, SC
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $86 total per night from Jul 20 to Jul 21
$86 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"I wish it was more handicap accessible but overall great property to stay at"

Reviewed on Jul 7, 2025

Comfort Inn Greenville - Haywood Mall
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

3 out of 5
65 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $81 total per night from Jul 15 to Jul 16
$81 total
Jul 15 - Jul 16
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. ...
"Maria at the front desk was so warm and welcoming. Place could use some sprucing up & they only had cranberry juice - the others were out."

Reviewed on Jul 11, 2025

La Quinta Inn & Suites by Wyndham Greenville Haywood
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd, Anderson, SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $65 total per night from Jul 20 to Jul 21
$65 total
Jul 20 - Jul 21
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Always enjoy staying at this location; clean rooms, easy access from highway and great restaurants nearby"

Reviewed on Jul 10, 2025

Days Inn by Wyndham Anderson
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Upstate South Carolina hotels

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

128 Interstate Blvd, Anderson, SC
$68 nightly
The price is $75 total per night from Jul 20 to Jul 21
$75 total
Jul 20 - Jul 21
Total includes taxes and fees
6.8/10 (795 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Upstate South Carolina hotel reviews by fellow wanderers

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Always enjoy staying at this location; clean rooms, easy access from highway and great restaurants nearby "
A verified traveler stayed at Days Inn by Wyndham Anderson
Days Inn by Wyndham Anderson
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