Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels
Hotel Hartness
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
$209 nightly
The price is $230 total per night from May 27 to May 28
$230 total
May 27 - May 28
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...
Our anniversary trip to this hotel was FABULOUS! Special thanks to Ciara, the Bartender. She was kind and gave excellent suggestions regarding different liquors and food tastings. Rashad, at the front desk, was funny and very friendly. Everyone that we encountered went out of their way to be helpful ...
Reviewed on Apr 29, 2026
Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$339 nightly
The price is $372 total per night from May 3 to May 4
$372 total
May 3 - May 4
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Clean room.
Reviewed on Apr 22, 2026
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from May 10 to May 11
$109 total
May 10 - May 11
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The staff were friendly, the facility was clean and the breakfast was great
Reviewed on Apr 30, 2026
Hyatt Place Greenville Downtown
128 East Broad Street Greenville SC
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $149 total per night from May 24 to May 25
$149 total
May 24 - May 25
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
The cookies are phenomenal. The staff was nice. My bed was comfy.
Reviewed on Apr 30, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from May 25 to May 26
$121 total
May 25 - May 26
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
We are being a charged for a stay that never happened, even with proof of cancellation!
Reviewed on Apr 30, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
$99 nightly
The price is $109 total per night from May 31 to Jun 1
$109 total
May 31 - Jun 1
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
The staff was great at check-in very helpful and quick. The Ruth Chris steakhouse attached to the hotel is a nice touch as well, they did an awesome breakfast buffet and to order breakfast.
Reviewed on Apr 30, 2026
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from May 17 to May 18
$121 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
It was ok
Reviewed on May 1, 2026
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $122 total per night from May 11 to May 12
$122 total
May 11 - May 12
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Great location , great place
Reviewed on Apr 29, 2026
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $100 total per night from May 25 to May 26
$100 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Parking easy, room very clean and updated and friendly staff. Elevators slow but that’s okay. Breakfast was not that great unfortunately.
Reviewed on Apr 30, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Upstate South Carolina hotels
Baymont by Wyndham Anderson Clemson
128 Interstate Blvd Anderson SC
$72 nightly
The price is $80 total per night from May 11 to May 12
$80 total
May 11 - May 12
Total with taxes and fees
7/10 Good! (873 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating
4 Star Hotels
39 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers
Hilton Greenville
3 out of 5
Posted 4 hours ago
Travelocity Verified Review
"It was ok"
A verified traveler stayed at Hilton Greenville
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