Book Hotels in Upstate South Carolina, SC

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Top Upstate South Carolina hotels

Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson
Free WiFi in public areas is available at this cottage.
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Opens in a new windowWooded Cottage - 3 Mi to Clemson University
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY, Greenville, SC
Fully refundableReserve now, pay when you stay
$276 nightly
The price is $304 total per night from Nov 30 to Dec 1
$304 total
Nov 30 - Dec 1
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
Chip and his staff is the best!!

Reviewed on Nov 7, 2025

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd, Greenville, SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Nov 23 to Nov 24
$92 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
After being stranded on I 26 after a tire blow out for almost 6 hours, we were welcomed with open arms as we had the vehicle towed to the local Mazda dealership. What a nice way to end a very stressful day. Thank you for the cup of milk. It made my day. Very friendly front desk staff.

Reviewed on Nov 4, 2025

Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
Fully refundable
$91 nightly
The price is $100 total per night from Nov 23 to Nov 24
$100 total
Nov 23 - Nov 24
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Front desk staff were pleasant and welcoming. The lobby is gorgeous.

Reviewed on Nov 8, 2025

Opens in a new windowCrowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $99 total per night from Nov 23 to Nov 24
$99 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
Staff is always very friendly and accommodating.

Reviewed on Nov 5, 2025

Opens in a new windowHilton Greenville
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd, Clemson, SC
$97 nightly
The price is $108 total per night from Nov 16 to Nov 17
$108 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Restaurant connected to hotel

Reviewed on Nov 4, 2025

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

3 out of 5
40 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $88 total per night from Nov 29 to Nov 30
$88 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Room was beautiful! Food was great !

Reviewed on Nov 2, 2025

Opens in a new windowHyatt Place Greenville/Haywood
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

2.5 out of 5
5009 Pelham Road, Greenville, SC
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $79 total per night from Nov 13 to Nov 14
$79 total
Nov 13 - Nov 14
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Free perks include full breakfast, free self parking, and a roundtrip airport shuttle. A 24-hour business ...
Clean, newly renovated rooms. Great breakfast and coffee. Easy check in and check out.

Reviewed on Nov 10, 2025

Opens in a new windowBest Western Greenville Airport Inn
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

3 out of 5
65 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $80 total per night from Nov 23 to Nov 24
$80 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. ...
Q

Reviewed on Nov 3, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Greenville Haywood
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Upstate South Carolina hotels

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

128 Interstate Blvd, Anderson, SC
$60 nightly
The price is $66 total per night from Nov 17 to Nov 18
$66 total
Nov 17 - Nov 18
Total with taxes and fees
7/10 Good! (830 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Upstate South Carolina hotel reviews by fellow wanderers

Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Clean, newly renovated rooms. Great breakfast and coffee. Easy check in and check out. "
A verified traveler stayed at Best Western Greenville Airport Inn
Best Western Greenville Airport Inn

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