Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $120 total per night from Nov 23 to Nov 24
$120 total
Nov 23 - Nov 24
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Everything"
Reviewed on Nov 12, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
$89 nightly
The price is $99 total per night from Dec 13 to Dec 14
$99 total
Dec 13 - Dec 14
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Great Location, Wonderful Staff Nice Stay"
Reviewed on Nov 12, 2026
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Dec 6 to Dec 7
$83 total
Dec 6 - Dec 7
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Days Inn by Wyndham Greenville
60 Roper Mountain Rd Greenville SC
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $67 total per night from Dec 1 to Dec 2
$67 total
Dec 1 - Dec 2
Total with taxes and fees
This motel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...
Hyatt Regency Greenville
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $153 total per night from Nov 25 to Nov 26
$153 total
Nov 25 - Nov 26
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$361 nightly
The price is $397 total per night from Dec 6 to Dec 7
$397 total
Dec 6 - Dec 7
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $113 total per night from Dec 11 to Dec 12
$113 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
Hyatt Place Greenville Downtown
128 East Broad Street Greenville SC
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $144 total per night from Nov 29 to Nov 30
$144 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Comfort Inn Greenville - Haywood Mall
246 Congaree Road Greenville SC
Fully refundable
$88 nightly
The price is $96 total per night from Dec 6 to Dec 7
$96 total
Dec 6 - Dec 7
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
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See all available properties in Upstate South Carolina
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Upstate South Carolina hotels
Baymont by Wyndham Anderson Clemson
128 Interstate Blvd Anderson SC
$63 nightly
The price is $70 total per night from Nov 22 to Nov 23
$70 total
Nov 22 - Nov 23
Total with taxes and fees
7/10 Good! (940 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating
4 Star Hotels
34 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers
Embassy Suites Greenville Golf Resort & Conference Center
5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Everything"
A verified traveler stayed at Embassy Suites Greenville Golf Resort & Conference Center
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