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Book Hotels in Upstate South Carolina, SC

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Tonight Oct 22 - Oct 23
This weekend Oct 23 - Oct 25
Next weekend Oct 30 - Nov 1

Most frequently booked Upstate South Carolina hotels

Price for 1 night 2 adults*

$65

Nov 1 - Nov 2

Per night/room

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.0 out of 5.0 831 Congaree Rd, Greenville, SC
4.8/5
(9 Reviews)
This hotel features a fitness center and a seasonal outdoor pool. Traveling on business? Take advantage of the 2 conference rooms, as well as the business center and free WiFi in public areas. Free self parking, a computer station, and luggage storage are also offered.
 
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$93

Nov 1 - Nov 2

Per night/room

Hyatt Place Greenville/Downtown

Hyatt Place Greenville/Downtown

3.0 out of 5.0 128 East Broad Street, Greenville, SC
4.7/5
(7 Reviews)
An indoor pool, valet parking, and wedding services are featured at this hotel. WiFi in public areas is free. Traveling on business? Take advantage of the 4 conference rooms, 24-hour business center, and express check-out.
 
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$139

Oct 25 - Oct 26

Per night/room

Aloft Greenville Downtown

Aloft Greenville Downtown

3.0 out of 5.0 5 North Laurens Street, Greenville, SC
4.4/5
(11 Reviews)
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, as well as the business center and free WiFi in public areas. Enjoy the fitness center and conveniences like a 24-hour front desk and laundry facilities.
 
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Top cheap Upstate South Carolina hotel deals

Price for 1 night 2 adults*

$60

Nov 2 - Nov 3

Per night/room

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

2.5 out of 5.0 128 Interstate Blvd, Anderson, SC
3.9/5
(14 Reviews)
This hotel features an outdoor pool and a 24-hour fitness center. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
 
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$52

Nov 19 - Nov 20

Per night/room

Days Inn by Wyndham Greenville

Days Inn by Wyndham Greenville

2.0 out of 5.0 60 Roper Mountain Rd, Greenville, SC
2.5/5
(27 Reviews)
This motel features a fitness center and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
 
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$50

Oct 29 - Oct 30

Per night/room

Baymont by Wyndham Greenville Woodruff Rd

Baymont by Wyndham Greenville Woodruff Rd

2.5 out of 5.0 31 Old Country Rd, Greenville, SC
3.3/5
(25 Reviews)
This hotel features a 24-hour fitness center and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.
 
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Top luxury Upstate South Carolina hotel deals

Price for 1 night 2 adults*

$169

Oct 25 - Oct 26

Per night/room

The Westin Poinsett Greenville

The Westin Poinsett Greenville

4.0 out of 5.0 120 South Main St, Greenville, SC
4.3/5
(20 Reviews)
This hotel features a restaurant, a fitness center, and a bar/lounge. Traveling on business? Take advantage of the 8 conference rooms, business center, and free airport shuttle. WiFi in public areas is free.
Reviewed on Nov 23, 2019

Love the location and charm of this historic hotel. Our room was spacious and very comfortable.

 
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$117

Nov 4 - Nov 5

Per night/room

Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5.0 220 N Main St, Greenville, SC
4.1/5
(18 Reviews)
The hotel's 24-hour fitness center, seasonal outdoor pool, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. A restaurant, a 24-hour front desk, and a coffee shop are also provided.
Reviewed on Sep 7, 2020

Where my room was located and the smell on chech in day.

 
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$60

Oct 25 - Oct 26

Per night/room

Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente

2.5 out of 5.0 231 N Pleasantburg Dr, Greenville, SC
3.1/5
(13 Reviews)
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business center, laundry service, and airport shuttle. Enjoy the fitness center and conveniences like a 24-hour front desk and free newspapers.
Reviewed on Sep 10, 2020

Rooms was clean and smelled good. Hallway by elevator had a bad smell.

 
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See all 1,034 Properties in Upstate South Carolina
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How much is a hotel room in Upstate South Carolina?

Hotels in Upstate South Carolina start at $50 per night. Prices and availability subject to change. Additional terms may apply.

Cheap Hotels in Upstate South Carolina

Pack your bags—it’s time to embark on a getaway. Whether you’re craving a solo retreat or promising your family a vacation to remember, book one of the best hotels in Upstate South Carolina. These hotels are located within easy access of the city’s hottest attractions and entertainment, so you won’t miss a beat while you’re in town. Spend the days exploring the local landmarks and the evenings getting to know the nightlife. After exploring the city from top to bottom, rest up at a hotel that speaks to you. Find the perfect place that matches your trip’s vibe, from a trendy boutique to family-friendly accommodations.

Allow us here at Travelocity to pair you with up Upstate South Carolina hotels that suit your vacation preferences. Discover places with convenient on-site restaurants, around-the-clock service, and pools where your kids can make a splash. Some hotels may boast fitness rooms and spa services, while others feature game rooms and Wi-Fi access. To top it all off, you’ll score cheap hotels in Upstate South Carolina that let you spend more on your activities and less on your lodging. Book and bundle your flight and hotel deals together today and save up to $537. It’s time to explore a new city, and break out of your routine.

Recent Upstate South Carolina hotel reviews by fellow wanderers

Courtyard Greenville-Spartanburg by Marriott

3.0 Travelocity Verified Review
There was a beautiful fire pit!! Though there was construction which made things loud and hard to focus trying to work. Hotel was decent. I used the gym while I was there. It was nice though I really wish the pool had be able to be used.
2 weeks ago by A verified traveler from Greenville, South Carolina
Open Courtyard Greenville-Spartanburg by Marriott hotel guest reviews

Hyatt Place Greenville/Haywood

4.0 Travelocity Verified Review
We were happy with most everything, however the grout in the shower had mold in the corner. The staff was excellent.
3 weeks ago by A verified traveler from Charleston SC
Open Hyatt Place Greenville/Haywood hotel guest reviews

Hampton Inn Spartanburg-North I-85

5.0 Travelocity Verified Review
Room was very clean. Due to Covid, breakfast bag to go was the only option. It was a good attempt at breakfast, but not really a viable option for us.
3 weeks ago by A verified traveler
Open Hampton Inn Spartanburg-North I-85 hotel guest reviews

Best Western Plus Greenville I-385 Inn & Suites

5.0 Travelocity Verified Review
The hotel and room looked great, clean, and the staff were fantastic! I wish I could remember the lady's name who checked us in because she was kind, friendly, and all around ray of sunshine.
4 weeks ago by A verified traveler
Open Best Western Plus Greenville I-385 Inn & Suites hotel guest reviews

Wingate by Wyndham - Greenville-Airport

5.0 Travelocity Verified Review
Very clean rooms, getting to the hotel was easy, and staff was very friendly.
1 month ago by A verified traveler from Greenville, sc
Open Wingate by Wyndham - Greenville-Airport hotel guest reviews

Lakeside Lodge Clemson

5.0 Travelocity Verified Review
Perfect location for visiting the Clemson campus and then hiking and exploring nearby waterfalls the next day. Several shops and restaurants in walking distance of hotel. The studio room with kitchenette was perfect! Staff was super friendly and helpful. Would absolutely stay here again!
2 months ago by A verified traveler
Open Lakeside Lodge Clemson hotel guest reviews

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.