Book Hotels in Upstate South Carolina, SC
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Top Upstate South Carolina hotels

Grand Bohemian Lodge Greenville, Autograph Collection
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$332 nightly
The price is $364 total per night from Mar 22 to Mar 23
$364 total
Mar 22 - Mar 23
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
Best hotel in the city (no doubt) located perfect, and the hotel decor is amazing which means it has everything for a 5 star hotel experience except the pool, and the service, the service was this times absolutely better than previous but still need more to get to the 5 star service
Reviewed on Feb 26, 2026

Hyatt Place Greenville Downtown
128 East Broad Street Greenville SC
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $153 total per night from Mar 15 to Mar 16
$153 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Great location, clean and polite staff
Reviewed on Mar 1, 2026

Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
$116 nightly
The price is $128 total per night from Mar 15 to Mar 16
$128 total
Mar 15 - Mar 16
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Everything was fine. Indoor pool was cold.
Reviewed on Mar 1, 2026

Hyatt Regency Greenville
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $163 total per night from Mar 8 to Mar 9
$163 total
Mar 8 - Mar 9
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Great room, good price, nice staff.
Reviewed on Mar 1, 2026

Courtyard by Marriott Greenville Haywood Mall
70 Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $110 total per night from Mar 15 to Mar 16
$110 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
The motel as a whole was very clean and well maintained. The staff was excellent and very helpful. I would highly recommend if you are looking for a great place to stay for a reasonable price.
Reviewed on Mar 2, 2026

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
$101 nightly
The price is $111 total per night from Mar 8 to Mar 9
$111 total
Mar 8 - Mar 9
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
We had a great stay, the room was clean and the staff were very helpful.
Reviewed on Mar 2, 2026

Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Mar 15 to Mar 16
$109 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
Friendly staff, clean rooms and comfortable bed
Reviewed on Mar 1, 2026

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Mar 5 to Mar 6
$101 total
Mar 5 - Mar 6
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The room was very clean, it was a room with a king bed and a sofa bed plus a microwave, mini fridge, coffee machine. The reception desk was very helpful when I had to do a late check in.
Reviewed on Mar 1, 2026

Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Mar 30 to Mar 31
$109 total
Mar 30 - Mar 31
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Very courteous staff. Especially the room staff
Reviewed on Mar 1, 2026
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See all available properties in Upstate South Carolina
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Upstate South Carolina hotels

Baymont by Wyndham Anderson Clemson
128 Interstate Blvd Anderson SC
$55 nightly
The price is $61 total per night from Mar 15 to Mar 16
$61 total
Mar 15 - Mar 16
Total with taxes and fees
7/10 Good! (856 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Upstate South Carolina with star-rating
Check Upstate South Carolina Hotels by Star Rating

4 Star Hotels
11 properties
Recent Upstate South Carolina hotel reviews by fellow wanderers

Hotel Hartness
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"The hotel had a wonderful smell when you walk in. They have very high-end lotions and hair products. Great lighting getting ready. Great lighting for reading. Overall the hotel was a 10 in my opinion."
A verified traveler stayed at Hotel Hartness
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