Book Hotels in Seneca, South Carolina

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Check prices in Seneca for tonight, Jun 7 - Jun 8
Jun 7 - Jun 8
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Jun 8 - Jun 9
This weekend
Check prices in Seneca for this weekend, Jun 9 - Jun 11
Jun 9 - Jun 11
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Jun 16 - Jun 18

Most frequently booked Seneca hotels

Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd, Seneca, SC
Free Cancellation
Reserve now, pay when you stay
5.27 mi from city center
The price is $109 per night
$109
per night
Jun 8 - Jun 9
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate the spa tub, poolside bar, and concierge services.
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd, Seneca, SC
Free Cancellation
Reserve now, pay when you stay
5.12 mi from city center
The price is $102 per night
$102
per night
Jul 4 - Jul 5
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business center. There's a gym on site, and a 24-hour front desk and a snack bar/deli are also provided.
Quality Inn Seneca US-123

Quality Inn Seneca US-123

2.5 out of 5
226 Hi Tech Rd, Seneca, SC
Free Cancellation
Reserve now, pay when you stay
0.16 mi from city center
The price is $83 per night
$83
per night
Jun 24 - Jun 25
A seasonal outdoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. Staff at the 24-hour front desk can provide around-the-clock assistance.
New! Peaceful Lakefront Home on Keowee! Only 7 Miles from Clemson!

New! Peaceful Lakefront Home on Keowee! Only 7 Miles from Clemson!

1.23 mi from city center
Get rates
A gym is featured at this vacation home, along with barbecue grills.
5🌟 Modern Lakefront Luxury Oasis · 270° Lake Views w/Dock & Hot Tub!

5🌟 Modern Lakefront Luxury Oasis · 270° Lake Views w/Dock & Hot Tub!

4.53 mi from city center
Get rates
A spa tub is featured at this vacation home, along with a garden and barbecue grills. There's fun for all ages with a playground and an arcade/game room.
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd, Clemson, SC
Free Cancellation
Reserve now, pay when you stay
7.2 mi from city center
The price is $92 per night
$92
per night
Jun 24 - Jun 25
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 2 conference rooms, as well as the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd, Clemson, SC
Free Cancellation
Reserve now, pay when you stay
7.27 mi from city center
The price is $88 per night
$88
per night
Jun 19 - Jun 20
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free self parking, a grocery/convenience store, and express check-in are also offered.
Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2 out of 5
102 Electric City Blvd, Anderson, SC
Free Cancellation
Reserve now, pay when you stay
15.48 mi from city center
The price is $80 per night
$80
per night
Jun 13 - Jun 14
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business center and free Internet in public areas. There's an outdoor pool on site, and laundry facilities and free newspapers are also offered.
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

2 out of 5
110 Sloan St, Clemson, SC
Free Cancellation
Reserve now, pay when you stay
6.55 mi from city center
The price is $179 per night
$179
per night
Jun 18 - Jun 19
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also offered.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top family friendly Seneca hotel deals

Top cheap Seneca hotel deals

  • Days Inn by Wyndham Seneca / Clemson Area

    Days Inn by Wyndham Seneca / Clemson Area

    11015 N Radio Station Rd, Seneca, SC
    The price is $68 per night from Jun 13 to Jun 14
    $68
    per night
    Jun 13 - Jun 14
    7/10 Good! (509 reviews)

Seize your some day

Seneca Hotel & Travel Guide\n

Wandering through Anderson? If you're looking to get a feel of the city, research places to base you adventure which are within a short drive from the excitement of Seneca. Within a 6-mile (10-kilometer) distance from central Seneca, you will find 4 suitable hotel and apartment options.

If you're seeking out a room within a short walk from the center of Seneca, Hampton Inn & Suites Seneca-Clemson Area and Best Western Executive Inn are ideal.

Our extensive database contains only a handful of no-frills accommodations in Seneca. The Quality Inn Seneca / Clemson is one such listing.

Look into the Hampton Inn Clemson and also the Liberty Hall Inn & Brandinis Cusine. The Hampton Inn Clemson is situated just 6 miles (10 kilometers) outside of the city center of Seneca. The Liberty Hall Inn & Brandinis Cusine, is located just 10 miles (16 kilometers) away. Other hotel options are the Holiday Inn Express Hotel & Suites Anderson-I-85 and the Holiday Inn Express & Suites Clemson.

Anyone who is excited to check out more of the rolling hills and foothills typical in this region of the country, you should make time for a few extra days in other destinations in Upstate South Carolina. It doesn't matter if you throw yourself at traditional pastimes, like mountain biking and hiking, or skip around the area to explore the attractions, you'll easily reserve the most comfortable hotels in the area.

The nearest hotels in Anderson are Clemson and Clemson. Clemson is 8 miles (12 kilometers) to the east of Seneca, while Clemson is 8 miles (12 kilometers) to the east. Clemson Travelocity-listed lodgings are the Courtyard Marriott Clemson and University Inn & Conference Center at Clemson. The Hotel Tillman and Days Inn Clemson are a selection of the hotel options in Clemson.

When watching stadium sport is your most-cherished pastime, visit Bon Secours Wellness Arena, which you will find 35 miles (55 kilometers) to the east of Seneca. Book Travelocity-listed accommodation near the action at the Courtyard by Marriott Greenville Downtown or the Hampton Inn & Suites Greenville Downtown RiverPlace.

If you are flying via Greenville-Spartanburg International Airport and want to book a Travelocity-listed hotel in the area, consider Greenville Marriott or Courtyard Greenville-Spartanburg by Marriott.

Seneca hotels essential information

Number of reviews
Accommodation
1,259 hotels
Lowest Price
$68
Highest Price
$179
Popular hotels
Lakeside Lodge Clemson, Tru by Hilton Seneca Clemson, Quality Inn Seneca US-123, New! Peaceful Lakefront Home on Keowee! Only 7 Miles from Clemson!, 5🌟 Modern Lakefront Luxury Oasis · 270° Lake Views w/Dock & Hot Tub!, Comfort Inn & Suites Clemson - University Area, Best Western Plus Clemson Hotel & Conference Center, Microtel Inn & Suites by Wyndham Anderson/Clemson, The Shepherd Hotel Downtown Clemson

Frequently asked questions

What are the top kid-friendly hotels in Seneca?
From cool amenities to extra room to move, kid-friendly hotels come with features that can help transform a great family vacation into an extraordinary one. These Seneca properties make vacationing with young ones a piece of cake: Quality Inn Seneca US-123 will help make your trip the best one yet. It comes with plenty of conveniences aimed at families, such as premium bedding and a swimming pool. Also consider staying at Vrbo Property. It comes with nearby hiking, a barbecue grill and plenty of opportunities to hang out as a family.
Where can I find cheap hotels in Seneca?
At Travelocity you’ll find really nice hotels in Seneca at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Seneca rather than in Seneca. We may find you even better rates, too.
How do I find the best Seneca hotel deals?
Simple! On Travelocity, look through the fantastic offers we’ve already found in Seneca then use our filters to find a great deal that’s perfect for you. Enter your travel dates, select the number of rooms you need, and we’ll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Seneca?
The cheapest hotel in Seneca is $68. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel’s location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Seneca?
There are 1,259 hotels in Seneca on Travelocity.
What are the best hotels in Seneca?
Seneca has so many great hotels to choose from at Travelocity — and it’s so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Seneca for you!
When is the best time to visit Seneca?
If you want the joy of a fun-filled trip in peak season, visit Seneca during . If you’d prefer the peace of off-season, book a stay during quieter months, such as .
When is the cheapest time to stay in Seneca?
Based on historic data is usually the cheapest month to visit Seneca. However, we have incredible deals all year round, so we’re confident you’ll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Seneca?
There are multiple hotels in Seneca that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We’ve got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Seneca. We have plenty of kid-friendly hotels in Seneca to choose from on Travelocity!
Why book a hotel in Seneca through Travelocity?
Because we have the top hotels in Seneca! We want to help you travel more and worry less. That’s why we’ve put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you’re getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Seneca on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Seneca hotel reviews by fellow wanderers

  • Inn @ Clemson

    Inn @ Clemson

    5 out of 5
    Posted 2 days ago
    Travelocity Verified Review
    "Watched college baseball regionals during our stay. Great weekend GO VOLS "
    A verified traveler stayed at Inn @ Clemson
    Inn @ Clemson

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