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Top hotels in Serenity Bay

Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

Deepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger

Seneca SC
$730 nightly
The price is $803 total per night from Jun 8 to Jun 9
$803 total
Jun 8 - Jun 9
Total with taxes and fees
This vacation home featured laundry facilities and barbecue grills.
"Host was great- answered all questions immediately House was perfect!"

Reviewed on May 10, 2026

Opens in a new windowDeepwater Cove on Lake Keowee. Complete with Dock and Kayaks. EV Charger
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $169 total per night from Jun 9 to Jun 10
$169 total
Jun 9 - Jun 10
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
"I am so impressed with this hotel. We were staying for my daughter's orientation at Clemson in May. Right around the corner from the university, inviting clean lobby, lovely room and bathroom, incredibly friendly and helpful staff. A first class establishment with an inspiring purpose that we will ..."

Reviewed on Jun 4, 2026

Opens in a new windowThe Shepherd Hotel Downtown Clemson
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3 out of 5
240 Madren Center Drive Clemson SC
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $154 total per night from Jun 8 to Jun 9
$154 total
Jun 8 - Jun 9
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...
"Ery nice and quiet. Comfy beds. Fitness center is small. Would come back and stay here again."

Reviewed on Jun 4, 2026

Opens in a new windowClemson University's James F. Martin Inn
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Jun 7 to Jun 8
$135 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
"Bedding was questionable but it was resolved quickly. Everything was nice especially the lake."

Reviewed on Jun 6, 2026

Opens in a new windowLakeside Lodge Clemson
Courtyard Marriott Clemson

Courtyard Marriott Clemson

3 out of 5
201 Canoy Ln Clemson SC
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $159 total per night from Jun 15 to Jun 16
$159 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax ...
"We were here for a wedding. The luggage carts were not made so you could hang up clothes. I had to make two trips up the elevator and hand carry my wife’s long dress ,,her other hanging clothes and my suit and hang up clothes. A normal cart would have made it so much easier. Just being picky about ..."

Reviewed on Jun 6, 2026

Opens in a new windowCourtyard Marriott Clemson
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
Fully refundable
$101 nightly
The price is $112 total per night from Jun 29 to Jun 30
$112 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Woke up to bathroom floor flooded. Couldn’t shower."

Reviewed on May 31, 2026

Opens in a new windowComfort Inn & Suites Clemson - University Area
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Jun 7 to Jun 8
$106 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"S tier breakfast"

Reviewed on Jun 1, 2026

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Fully refundable
$91 nightly
The price is $99 total per night from Jun 9 to Jun 10
$99 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"Breakfast needs more items to choose from."

Reviewed on May 24, 2026

Opens in a new windowQuality Inn Seneca Clemson Area US-123
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $91 total per night from Jun 9 to Jun 10
$91 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Great overall stay. Visited Clemson for the weekend"

Reviewed on Jun 2, 2026

Opens in a new windowInn @ Clemson
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Serenity Bay Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Serenity Bay area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Serenity Bay to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Serenity Bay are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Serenity Bay hotel reviews by fellow wanderers

Courtyard Marriott Clemson

Courtyard Marriott Clemson

3 out of 5
Posted 3 hours ago
Travelocity Verified Review
"We were here for a wedding. The luggage carts were not made so you could hang up clothes. I had to make two trips up the elevator and hand carry my wife’s long dress ,,her other hanging clothes and my suit and hang up clothes. A normal cart would have made it so much easier. Just being picky about this however it is time for update on carpet in hallways and in the room.They are pretty worn out."
A verified traveler stayed at Courtyard Marriott Clemson
Courtyard Marriott Clemson

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