Book Hotels in Central, SC
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Central hotels

NEW!Lakefront retreat with huge dock, private cove. Perfect for Clemson Football
"House was perfect for Clemson graduation weekend. Great location and lots of room for our small group to spread out. Host is so gracious about keeping a stocked kitchen with coffee/tea supplies, snacks, etc. The driveway is no joke though! Would definitely stay here again."
Reviewed on May 20, 2026

The Shepherd Hotel Downtown Clemson
"Staff was very friendly and helpful."
Reviewed on Jun 11, 2026

Clemson University's James F. Martin Inn
"This was such a great hotel! The staff were so nice and friendly, the hotel and room were clean and comfy. I would definitely stay again and recommend to others."
Reviewed on Jun 12, 2026

Lakeside Lodge Clemson
"Pool was great, close to town. Room was well stocked with kitchen stuff. Loved the gym as well. One of the front desk employees was not very nice to a guest coming in. Room wasn't ready and he wasn't happy. She told him she couldn't help that staff had called in sick and they were short staffed. ..."
Reviewed on Jun 11, 2026

Comfort Inn & Suites Clemson - University Area
"Quiet clean good for the price"
Reviewed on Jun 9, 2026

Best Western Plus Clemson Hotel & Conference Center
"Some of the security lights were out."
Reviewed on Jun 13, 2026

Days Inn by Wyndham Anderson
"The room was clean… but very musky smelling. Not like the pictures. Okay for the price."
Reviewed on Jun 13, 2026

Inn @ Clemson
"While the rooms were fine, we found an outdated bath/shower area and also TV as well. The beds and linens were comfortable and nice, but this is just an older hotel."
Reviewed on Jun 11, 2026

Quality Inn Seneca Clemson Area US-123
"Room was easy access to the parking bathroom was accessible for person with limited walking ability staff was very friendly and helpful the pool was not open"
Reviewed on Jun 9, 2026
Central Hotel & Travel Guide\n
If you are intending on journeying through Anderson and get struck by the urge to spend time in Central, as a savvy traveler, you would be wise to book in advance through Travelocity to make sure you end up with the most appropriate place to kick up your feet. With 9 places to stay on Travelocity within a 6-mile (10-kilometer) radius of Central, it will be easy finding somewhere that works for you.
Accommodation options that aren't far from the business district of Central include the Holiday Inn Express & Suites Clemson and Courtyard Marriott Clemson.
You should investigate the Hampton Inn Clemson and also the Hampton Inn & Suites Seneca-Clemson Area. The Hampton Inn Clemson is located just 4 miles (7 kilometers) away from the city center of Central. The Hampton Inn & Suites Seneca-Clemson Area, is situated 9 miles (15 kilometers) away. Some other places to rest your head include the The Bleckley Inn and the Liberty Hall Inn & Brandinis Cusine.
For those who are wanting to see more of the rolling hills and foothills common in this area of the country, you would be wise to take some time in other parts of Upstate South Carolina. Go mountain biking or make a trip to the region's diverse places of interest. Great Travelocity-listed hotels can cater to your needs.
The nearest places to stay in Anderson are Seneca and Clemson. Seneca is 11 miles (17 kilometers) to the west of Central, while Clemson is 4 miles (6 kilometers) to the west. Rooms in Seneca include the Best Western Executive Inn and Quality Inn Seneca / Clemson. The University Inn & Conference Center at Clemson and Hotel Tillman are a selection of the Travelocity-registered lodgings in Clemson.
Before you leave Anderson, you should certainly ensure you join locals to watch some local sport. Visit Bon Secours Wellness Arena, to the east of Central. Stay in the middle of the action at the Courtyard by Marriott Greenville Downtown or the Hampton Inn & Suites Greenville Downtown RiverPlace.
When you are traveling via Greenville-Spartanburg International Airport and are looking to book a Travelocity-listed room in the area, why not consider Greenville Marriott or Courtyard Greenville-Spartanburg by Marriott.
Frequently asked questions
Recent Central hotel reviews by fellow wanderers

Comfort Suites Piedmont - Greenville South
"When we arrived all the trash was overflowing from the bins. I don’t know for a few bucks more u can get something better"
Explore More Ways to Travel with Travelocity
- Hotels near NewSpring Church
- Hotels near South Carolina Botanical Gardens
- Hotels near Larry W. Abernathy Waterfront Park
- Normandy Shores Hotels
- Northlake Hotels
- La France Hotels
- Hotels near Clemson University
- Seneca Hotels
- Hotels near Foothills Playhouse
- Hotels near Lake Keowee
- Hotels near Tri-County Technical College
- Pickens Hotels
- B&B in Pendleton
- Cabins in Pendleton
- Cottages in Pendleton
- Extended Stay Hotels in Pendleton
- Pet Friendly Hotels in Pendleton
- Pendleton Hotels
- Motels in Pendleton
- Villas in Pendleton
- Indian Oaks Hotels
- Easley Hotels
- Hotels near Anderson Mall
- Hotels near Brooks Center for the Performing Arts
- Townville Hotels
- Liberty Hotels
- Welcome Hotels
- Hotels near Southern Wesleyan University
- 5 Star Hotels in Clemson
- Farmstay in Clemson
- Apartments in Clemson
- B&B in Clemson
- Cabins in Clemson
- Condos in Clemson
- Cottages in Clemson
- Extended Stay Hotels in Clemson
- Guest Houses in Clemson
- Boutique Hotels in Clemson
- Cheap Hotels in Clemson
- Kid Friendly Hotels in Clemson
- Golf Resorts & in Clemson
- Historic Hotels in Clemson
- Hotels with Pools in Clemson
- Hotels with Balconies in Clemson
- Hotels with Bar in Clemson
- Hotels with Hot Tubs in Clemson
- Hotels with an Indoor Pool in Clemson
- Hotels with smoking rooms in Clemson
- Hotels on the Lake in Clemson
- Luxury Hotels in Clemson
- Pet Friendly Hotels in Clemson
- Romantic Getaways & Hotels in Clemson
- Spa Resorts & in Clemson
- Clemson Hotels
- Houseboats in Clemson
- Motels in Clemson
- Vacation Homes in Clemson
- Rv Parks in Clemson
- Resorts in Clemson
- Villas in Clemson
- Sandy Springs Hotels
- Hotels near T. Ed Garrison Arena
- Hotels near Keowee Key Golf Course
- Serenity Bay Hotels
- Hotels near Fort Hill
- Hotels near J.B. Red Owens Sports Complex
- Hotels near Memorial Stadium
- Hotels near Littlejohn Coliseum
- Flights to Pendleton
- Flights to Clemson
- Flights from El Paso to Clemson
- Flights from Anchorage to Clemson
- Flights from Boston to Clemson
- Flights from Chicago to Clemson
- Flights from Houston to Clemson
- Flights from Indianapolis to Clemson
- Flights from Miami to Clemson
- Flights from New York to Clemson
- Flights from Orlando to Clemson
- Flights from Phoenix to Clemson
- Flights from Washington to Clemson
- Flights from Sacramento to Clemson
- Flights from Pittsburgh to Clemson
- Flights from Milwaukee to Clemson
- Flights from Jacksonville to Clemson
- Flights from Louisville to Clemson
- Flights from San José to Clemson
- Flights from Mumbai to Clemson
- Flights from Bristol to Clemson






