Find and compare 2 Star hotels in Upstate South Carolina

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Top Upstate South Carolina 2 Star hotels

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Nov 20 to Nov 21
$70 total
Nov 20 - Nov 21
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.6/10 Good! (1,002 reviews)
The room was clean and located in a quiet area. The staff was polite and helped us quickly when we asked for an extra towel both days. The only negative we had was the free breakfast that had little to offer in the way of variety. Our second morning there we purposely ate breakfast at a restaurant ...

Reviewed on Nov 13, 2025

Opens in a new windowDays Inn by Wyndham Anderson
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Nov 23 to Nov 24
$92 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
9/10 Wonderful! (1,400 reviews)
Beautiful spacious room very clean.Breakfast was great except whrnn

Reviewed on Nov 18, 2025

Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $103 total per night from Nov 23 to Nov 24
$103 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8.2/10 Very Good! (1,003 reviews)
Restaurant connected to hotel

Reviewed on Nov 4, 2025

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $89 total per night from Dec 7 to Dec 8
$89 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
7.8/10 Good! (659 reviews)
Clean room w fridge and microwave Comfy bed

Reviewed on Nov 15, 2025

Opens in a new windowQuality Inn Seneca Clemson Area US-123
ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

2 out of 5
490 W Blackstock Road Spartanburg SC
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $81 total per night from Nov 20 to Nov 21
$81 total
Nov 20 - Nov 21
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
8/10 Very Good! (267 reviews)
Perfect room. Clean comfortable and the staff is very friendly

Reviewed on Nov 13, 2025

Opens in a new windowECHO Suites Extended Stay by Wyndham Spartanburg
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

2 out of 5
1024 Woodruff Rd Greenville SC
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $78 total per night from Dec 3 to Dec 4
$78 total
Dec 3 - Dec 4
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
8.2/10 Very Good! (1,004 reviews)
Room was clean and staff was helpful. That is all I was looking for. A very comfortable stay for a very reasonable price.

Reviewed on Nov 14, 2025

Opens in a new windowMicrotel Inn & Suites by Wyndham Greenville / Woodruff Rd
Comfort Suites Greenville Airport

Comfort Suites Greenville Airport

2.5 out of 5
1371 Garlington Road Greenville SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $111 total per night from Dec 14 to Dec 15
$111 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
9.2/10 Wonderful! (1,001 reviews)
Room was very good and clean. The staff was great

Reviewed on Nov 15, 2025

Opens in a new windowComfort Suites Greenville Airport
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Nov 27 to Nov 28
$106 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
8.2/10 Very Good! (1,003 reviews)
Room was clean. The hotel was quiet for a college town and a night game. Staff was polite and friendly.

Reviewed on Nov 14, 2025

Opens in a new windowComfort Inn & Suites Clemson - University Area
Motel 6 Greenville, SC

Motel 6 Greenville, SC

2 out of 5
2015 Wade Hampton Blvd Greenville SC
Fully refundable
$51 nightly
The price is $56 total per night from Nov 19 to Nov 20
$56 total
Nov 19 - Nov 20
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
5/10 (677 reviews)
I had never stayed here before but the rates were much better than all the others so I was kind of skeptical at first. But upon arriving and checking the room out, I was pleasantly pleased. It comes with a small kitchen area which most do not, especially for the price. I would definitely stay here ...

Reviewed on Nov 8, 2025

Opens in a new windowMotel 6 Greenville, SC
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road Greenville SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $106 total per night from Nov 19 to Nov 20
$106 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8/10 Very Good! (1,004 reviews)
Nice

Reviewed on Nov 12, 2025

Opens in a new windowComfort Inn Greenville - Haywood Mall
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

2 Star Hotels Upstate South Carolina

Looking to break out of your routine for some much needed rest and relaxation? Or maybe you’ve already decided it’s time for a trip and are trying to find affordable hotels in Upstate South Carolina that won’t bust your travel budget?

Upstate South Carolina 2 star hotels will give you everything you need to enjoy the city like a local, saving a ton of money so you can hit all the hot spots in town.

Have a delicious breakfast at your hotel to fuel up for your day of sightseeing, then enjoy amenities like fresh towels and linens, as well as a nice hot shower to unwind after a busy day of experiencing everything the city has to offer.

As you explore a new locale, or one you love to visit over and over, you can rest easy knowing you’re staying in a great hotel that lets you discover Upstate South Carolina and welcomes you back to a clean, comfortable room at night.

Browse Travelocity’s wide selection of 2 star hotels in Upstate South Carolina and find one that’s perfectly priced and places you next to all the best activities and sights. The town is your oyster, and we can help you seek out its secrets while sticking to your budget.

Recent Upstate South Carolina hotel reviews by fellow wanderers

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