Find and compare 2 Star hotels in Upstate South Carolina

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Top Upstate South Carolina 2 Star hotels

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Jun 21 to Jun 22
$92 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
9.2/10 Wonderful! (1,514 reviews)
"The entire staff was awesome! The breakfast was incredible. I would highly recommend this hotel to anyone traveling on the area!!"

Reviewed on Jun 14, 2026

Opens in a new windowBest Western Plus Greenville I-385 Inn & Suites
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road Greenville SC
Fully refundable
$97 nightly
The price is $106 total per night from Jun 18 to Jun 19
$106 total
Jun 18 - Jun 19
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8/10 Very Good! (1,018 reviews)
"We had a nice breakfast before we headed back on the road."

Reviewed on Jun 7, 2026

Opens in a new windowComfort Inn Greenville - Haywood Mall
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
$123 nightly
The price is $135 total per night from Jun 15 to Jun 16
$135 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
9/10 Wonderful! (1,014 reviews)
"Pool was great, close to town. Room was well stocked with kitchen stuff. Loved the gym as well. One of the front desk employees was not very nice to a guest coming in. Room wasn't ready and he wasn't happy. She told him she couldn't help that staff had called in sick and they were short staffed. ..."

Reviewed on Jun 11, 2026

Opens in a new windowLakeside Lodge Clemson
Baymont by Wyndham Greenville Woodruff Rd

Baymont by Wyndham Greenville Woodruff Rd

2.5 out of 5
31 Old Country Rd Greenville SC
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $80 total per night from Jul 12 to Jul 13
$80 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
7/10 Good! (1,004 reviews)
"It’s great overall , recommend"

Reviewed on Jun 13, 2026

Opens in a new windowBaymont by Wyndham Greenville Woodruff Rd
Urban Boutique Hotel, BW Signature Collection

Urban Boutique Hotel, BW Signature Collection

2.5 out of 5
536 Wade Hampton Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $75 total per night from Jun 21 to Jun 22
$75 total
Jun 21 - Jun 22
Total with taxes and fees
A bar/lounge and a 24-hour front desk are featured at this motel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and ...
8/10 Very Good! (1,015 reviews)
"The motel itself was fine, basic mom and pop motel. It has been updated. However, the bed was extremely uncomfortable. The mattress was a "mattress in a box"--foam mattress that you release from a roll and let it expand. Idk if it is just worn out from use or what, but there was no support at all. ..."

Reviewed on Jun 9, 2026

Opens in a new windowUrban Boutique Hotel, BW Signature Collection
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Jun 15 to Jun 16
$106 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8.2/10 Very Good! (1,005 reviews)
"Some of the security lights were out."

Reviewed on Jun 13, 2026

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport

2.5 out of 5
205 Entertainment Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $74 total per night from Jun 16 to Jun 17
$74 total
Jun 16 - Jun 17
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage and laundry facilities are also provided.
7.8/10 Good! (480 reviews)
"Quiet, clean rooms, comfortable beds and the staff is great."

Reviewed on Jun 13, 2026

Opens in a new windowWoodspring Suites Greenville Airport
Days Inn by Wyndham Greenville

Days Inn by Wyndham Greenville

2 out of 5
60 Roper Mountain Rd Greenville SC
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $68 total per night from Jun 28 to Jun 29
$68 total
Jun 28 - Jun 29
Total with taxes and fees
This motel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...
5.6/10 (1,015 reviews)
"Bedbugs Didn’t even stay 10 mins there"

Reviewed on Jun 12, 2026

Opens in a new windowDays Inn by Wyndham Greenville
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

2.5 out of 5
458 West Blackstock Road Spartanburg SC
Fully refundable
$90 nightly
The price is $99 total per night from Jul 5 to Jul 6
$99 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
8.2/10 Very Good! (1,020 reviews)
"Whenever I come to the Spartanburg area I always Comfort Inn as my home away from home. Thank you very much for your hospitality."

Reviewed on Jun 13, 2026

Opens in a new windowComfort Suites At WestGate Mall
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Fully refundable
$91 nightly
The price is $99 total per night from Jun 21 to Jun 22
$99 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
8/10 Very Good! (713 reviews)
"Room was easy access to the parking bathroom was accessible for person with limited walking ability staff was very friendly and helpful the pool was not open"

Reviewed on Jun 9, 2026

Opens in a new windowQuality Inn Seneca Clemson Area US-123
Don't see what you're looking for?
See all available properties in Upstate South Carolina
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

2 Star Hotels Upstate South Carolina

Looking to break out of your routine for some much needed rest and relaxation? Or maybe you’ve already decided it’s time for a trip and are trying to find affordable hotels in Upstate South Carolina that won’t bust your travel budget?

Upstate South Carolina 2 star hotels will give you everything you need to enjoy the city like a local, saving a ton of money so you can hit all the hot spots in town.

Have a delicious breakfast at your hotel to fuel up for your day of sightseeing, then enjoy amenities like fresh towels and linens, as well as a nice hot shower to unwind after a busy day of experiencing everything the city has to offer.

As you explore a new locale, or one you love to visit over and over, you can rest easy knowing you’re staying in a great hotel that lets you discover Upstate South Carolina and welcomes you back to a clean, comfortable room at night.

Browse Travelocity’s wide selection of 2 star hotels in Upstate South Carolina and find one that’s perfectly priced and places you next to all the best activities and sights. The town is your oyster, and we can help you seek out its secrets while sticking to your budget.

Recent Upstate South Carolina hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity