Upstate South Carolina Vacation Packages 2026 from $643

Upstate South Carolina flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Fox Run at Lake Lure

$643

per person

Jul 11 - Jul 16

found 5 hours ago

Roundtrip non-stop flight included

Tampa (TPA) to Asheville (AVL)

A full-service spa, a water park, and 3 hot tubs are all featured at this luxury aparthotel. Bring the family and enjoy the lazy river, children's pool, and playground. Enjoy the indoor pool and perks like free self parking.

The Radical Asheville, Tapestry Collection by Hilton

River Arts District

$674

per person

Jul 11 - Jul 16

found 1 day ago

Roundtrip non-stop flight included

Tampa (TPA) to Asheville (AVL)

This hotel features a restaurant and 2 bars/lounges. Enjoy the 24-hour gym and perks like free WiFi. Self parking, a coffee shop, and a picnic area are also offered.

The Restoration Asheville

Downtown Asheville

Save 100% on your flight

$1,020

per person

Jul 11 - Jul 16

found 1 day ago

Roundtrip non-stop flight included

Tampa (TPA) to Asheville (AVL)

This smoke-free hotel's 3 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. There's fun for all ages with a bowling alley and an arcade/game room, and complimentary bicycles are available on site. Enjoy the a rooftop terrace and free perks like continental breakfast and an area shuttle.

The Omni Grove Park Inn & Spa

Grove Park- Sunset

Save 100% on your flight

$1,279

per person

Jul 11 - Jul 16

found 1 day ago

Roundtrip non-stop flight included

Tampa (TPA) to Asheville (AVL)

This luxury resort features a golf course, a full-service spa, and 4 restaurants. Families will appreciate kid-friendly dining and babysitting, along with mountain biking. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free WiFi.

Zelda Dearest

Downtown Asheville

$848

per person

Jul 11 - Jul 16

found 1 day ago

Roundtrip non-stop flight included

Tampa (TPA) to Asheville (AVL)

A bar/lounge and concierge services are featured at this hotel, along with self parking. WiFi in public areas is free. Luggage storage and wedding services are also provided.

Top Upstate South Carolina hotels deals

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

851 Congaree Rd Greenville SC

Free Cancellation

$116 total

per night

May 17 - May 18

This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Unwind with a drink at one of the 2 bars/lounges and enjoy free perks like free self parking and an area shuttle.

Pool

Free airport shuttle

Embassy Suites Greenville Golf Resort & Conference Center

670 Verdae Blvd Greenville SC

Free Cancellation

Reserve now, pay when you stay

$131 total

per night

May 24 - May 25

A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy the outdoor pool and free buffet breakfast each morning.

Pool

Breakfast included

Grand Bohemian Lodge Greenville, Autograph Collection

44 EAST CAMPERDOWN WAY Greenville SC

Free Cancellation

Reserve now, pay when you stay

$396 total

per night

May 31 - Jun 1

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A lobby fireplace, a communal living room, and dry cleaning are also on offer.

Spa

Pet friendly

Hilton Greenville

45 W Orchard Park Dr Greenville SC

Free Cancellation

Reserve now, pay when you stay

$117 total

per night

May 24 - May 25

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, and laundry service. Self parking, a terrace, and a garden are also offered.

Pet friendly

Free WiFi

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

Free Cancellation

Reserve now, pay when you stay

$92 total

per night

May 31 - Jun 1

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Pool

Breakfast included

Hyatt Regency Greenville

220 N Main St Greenville SC

Free Cancellation

Reserve now, pay when you stay

$163 total

per night

May 17 - May 18

This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a seasonal outdoor pool on site, and concierge services and wedding services are also offered.

Pool

Pet friendly

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Clemson University

5/5(423 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

Falls Park Liberty Bridge in Downtown Greenville South Carolina SC

Falls Park on the Reedy

4.5/5(594 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.

Fred W. Symmes Chapel

5/5(12 reviews)

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.

Frequently asked questions

How much are vacation packages to Upstate South Carolina?

Travelocity offers great package deals to Upstate South Carolina, including hotels and flights, starting from as low as $643. With all the cash you save, you could throw in some cool tours or possibly even add a couple of extra days to your exciting adventure.

Where can I get the best vacation package deals for Upstate South Carolina?

There are sensational Upstate South Carolina package deals to be snapped up with Travelocity. Did you know we partner with as many as 400 airlines and 1,000,000 properties around the world? Keep that in mind the next time you're ready to check another place off your must-visit list.

Why should I purchase my Upstate South Carolina vacation package with Travelocity?

Whether you're on the hunt for the ultimate unplugged vacation or you crave the fun and excitement of a towering metropolis, booking everything with Travelocity saves you time, money and hassle. No need to scour through hundreds of different websites for the best deal — our Price Match Guarantee ensures you'll always get the lowest possible price, and our professional customer service experts are available 24/7.

Can I save on my Upstate South Carolina car rental if I book it with hotels and flights?

Definitely. And our Upstate South Carolina vacation packages will help you do it. In just a few clicks you can save cash as well as time by bundling your bookings. Collect the keys to your rental car then chart your own course. Looking for things to do? Add some activities or experiences to your package and make savings on those too.

Which airport is best for Upstate South Carolina?

If you're flying into Upstate South Carolina, you'll probably be touching down at Greenville-Spartanburg Intl. Airport (GSP) or Asheville Regional Airport (AVL).

What is there to do in Upstate South Carolina?

Upstate South Carolina boasts hidden gems around every turn, but make sure you see Clemson University and Lake Keowee while you're in town. These attractions shouldn't be missed.