Upstate South Carolina , SC Pet Friendly Hotels

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Top Upstate South Carolina Pet Friendly Hotels

Drury Inn & Suites Greenville

Drury Inn & Suites Greenville

10 Carolina Point Pkwy, Greenville, SC
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $131 total per night from Nov 9 to Nov 10
$131 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.4/10 Exceptional! (1,007 reviews)
The staff were all extremely friendly and helpful. It is very nice having the option for a free dinner and breakfast. The rooms are definitely dated and my room was so loud. This hotel is right off an interstate and busy main road so the road noise is constant 24 hours a day. The walls are thin, ...

Reviewed on Oct 26, 2025

Opens in a new windowDrury Inn & Suites Greenville
Aloft Greenville Downtown

Aloft Greenville Downtown

5 North Laurens Street, Greenville, SC
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $138 total per night from Nov 24 to Nov 25
$138 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9/10 Wonderful! (1,000 reviews)
Loved our stay! Hotel had super easy check in, friendly staff, hip feeling and awesome location! Nice lobby/bar area to hang out with friends and have super yummy cocktails as well! Highly recommend!

Reviewed on Oct 19, 2025

Opens in a new windowAloft Greenville Downtown
Country Inn & Suites by Radisson, Anderson, SC

Country Inn & Suites by Radisson, Anderson, SC

116 Interstate Blvd, Anderson, SC
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $121 total per night from Nov 13 to Nov 14
$121 total
Nov 13 - Nov 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
8.2/10 Very Good! (1,006 reviews)
Staff friendly, safe well lit area and convenience to many restaurants and a movie theater.

Reviewed on Oct 12, 2025

Opens in a new windowCountry Inn & Suites by Radisson, Anderson, SC
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $104 total per night from Nov 23 to Nov 24
$104 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
8.2/10 Very Good! (1,001 reviews)
The room was clean, plenty of pillows and liked the mini fridge, microwave and condiments.

Reviewed on Oct 28, 2025

Opens in a new windowComfort Inn & Suites Clemson - University Area
Best Western Greenville Airport Inn

Best Western Greenville Airport Inn

5009 Pelham Road, Greenville, SC
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $79 total per night from Nov 3 to Nov 4
$79 total
Nov 3 - Nov 4
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Free perks include full breakfast, free self parking, and a roundtrip airport shuttle. A 24-hour business ...
7.6/10 Good! (1,022 reviews)
Clean room, great breakfast

Reviewed on Oct 25, 2025

Opens in a new windowBest Western Greenville Airport Inn
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

65 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $73 total per night from Nov 2 to Nov 3
$73 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. ...
7.2/10 Good! (1,095 reviews)
Room was great

Reviewed on Oct 31, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Greenville Haywood
Baymont by Wyndham Greenville Woodruff Rd

Baymont by Wyndham Greenville Woodruff Rd

31 Old Country Rd, Greenville, SC
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $70 total per night from Nov 7 to Nov 8
$70 total
Nov 7 - Nov 8
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
6.8/10 (1,001 reviews)
The young lady at this property who checked me in was so amazing. She is the reason I gave this property 4 stars instead of 3. I didn't have any issues at the hotel. It served it's purpose.

Reviewed on Oct 28, 2025

Opens in a new windowBaymont by Wyndham Greenville Woodruff Rd
Red Roof Inn Spartanburg – I-26

Red Roof Inn Spartanburg – I-26

6765 Pottery Rd, Spartanburg, SC
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $67 total per night from Nov 16 to Nov 17
$67 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
6.8/10 (728 reviews)
Any property was very clean the room very clean we were very pleased stuff excellent.. Good to know that they are pet family friendly

Reviewed on Oct 20, 2025

Opens in a new windowRed Roof Inn Spartanburg – I-26
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

It’s hard to leave for a trip when the last image you have is of your four-legged best friend staring out the living-room window with those sad eyes as you drive away. You don’t have to leave Spot behind any longer, he can finally join you on your adventures.

Turn your trip into a family getaway by booking a stay at one of the pet-friendly hotels in Upstate South Carolina for you and your furry kids. No more sending them to pet hotels or leaving them home alone to run amok in the house. Upstate South Carolina pet-friendly hotels are perfect for weekend escapes with your pooch, kitty, bird, or fish. These accommodations not only welcome your pets, but they offer many services to help make your stay more relaxing. Things like on-site grooming and complimentary dog walking are some of the amenities provided. In most cases, you’ll also be near outdoor spaces like dog parks if you both need some exercise, as well as pet-friendly restaurants.

Don’t ever feel guilty about leaving your beloved Maximus behind on a trip again. Travelocity wants to help the both of you enjoy a wonderful vacation together. Search our extensive inventory of the best pet-friendly hotels in Upstate South Carolina and book your stay now.

Upstate South Carolina hotels essential information

Accommodation
2,859 hotels
Lowest Price
$67
Highest Price
$138
Popular hotels
Aloft Greenville Downtown, La Quinta Inn & Suites by Wyndham Greenville Haywood, Best Western Greenville Airport Inn, Country Inn & Suites by Radisson, Anderson, SC, Baymont by Wyndham Greenville Woodruff Rd, Drury Inn & Suites Greenville, Comfort Inn & Suites Clemson - University Area, Red Roof Inn Spartanburg – I-26

Recent Upstate South Carolina hotel reviews by fellow wanderers

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