Explore top 2025 4 Star Hotels in Greenville

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Top Greenville 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

44 EAST CAMPERDOWN WAY, Greenville, SC

Fully refundableReserve now, pay when you stay

$267 nightly

$294 total

Sep 28 - Sep 29

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...

The Westin Poinsett Greenville

120 South Main St, Greenville, SC

Fully refundableReserve now, pay when you stay

$189 nightly

$208 total

Sep 28 - Sep 29

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free ...

Greenville Marriott

One Parkway E, Greenville, SC

Fully refundableReserve now, pay when you stay

$132 nightly

$145 total

Sep 11 - Sep 12

Total with taxes and fees

This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-in, ...

Mint House Greenville - Downtown

101 Falls Park Dr, Greenville, SC

$135 nightly

$149 total

Sep 28 - Sep 29

Total with taxes and fees

A 24-hour gym is featured at this apartment, along with express check-in and express check-out. Laundry facilities are provided for your convenience.

Hotel Hartness

120 Halston Avenue, Greenville, SC

Fully refundableReserve now, pay when you stay

$209 nightly

$230 total

Sep 14 - Sep 15

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...

Park Place Apartments by Landing

300 Hammett St, Greenville, SC

This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A gym and a virtual front desk are also provided.

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34 Allen St

34 Allen Street, Greenville, SC

This vacation home features free self parking and a garden. Luggage storage is also provided.

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140 Catlin Circle

140 Catlin Circle, Greenville, SC

This vacation home features a garden, laundry facilities, and free self parking. Luggage storage and barbecue grills are also provided.

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Randall St , 202/204

202 Randall Street, Greenville, SC

This vacation home doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, luggage storage, and laundry facilities are also on ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Greenville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Greenville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Greenville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Greenville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.