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Top Santo Tomas Station hotels

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.99 mi from Santo Tomas Station
$122 nightly
The price is $135 total per night
$135 total
Dec 15 - Dec 16
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Pool
Breakfast included

Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
Free Cancellation
Reserve now, pay when you stay
1.17 mi from Santo Tomas Station
$157 nightly
The price is $175 total per night
$175 total
Dec 19 - Dec 20
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. You'll appreciate the gym, bar/lounge, and coffee shop.
Pool
Spa

Megapolis Hotel Panamá
Avenida Balboa Panama City
Free Cancellation
Reserve now, pay when you stay
1.07 mi from Santo Tomas Station
$131 nightly
The price is $144 total per night
$144 total
Dec 18 - Dec 19
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.59 mi from Santo Tomas Station
$180 nightly
The price is $198 total per night
$198 total
Dec 16 - Dec 17
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly dining, and babysitting. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free WiFi.
Pool
Spa

Marriott Panama Hotel
Roosevelt Ave., Allbrook Mall Panama City Panama
Free Cancellation
Reserve now, pay when you stay
1.38 mi from Santo Tomas Station
$142 nightly
The price is $156 total per night
$156 total
Dec 12 - Dec 13
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the a rooftop terrace and visit the 2 bars/lounges and poolside bar for drinks.
Pool
Pet friendly

Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
Free Cancellation
Reserve now, pay when you stay
6.14 mi from Santo Tomas Station
$272 nightly
The price is $272 total per night
$272 total
Dec 19 - Dec 20
Total with taxes and fees
A full-service spa, a nightclub, and 4 outdoor pools are all featured at this all-inclusive property. Spend a day at the beach kayaking, or relax with free beach cabanas and sun loungers. There's fun for all ages with a free kid's club and mini golf, and in-room childcare is an added bonus.
Pool
Breakfast included

Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla Panama City Panama
Free Cancellation
Reserve now, pay when you stay
1.14 mi from Santo Tomas Station
$108 nightly
The price is $119 total per night
$119 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included

Principe Hotel and Suites
Via Argentina Panama City Panama
Free Cancellation
Reserve now, pay when you stay
1.17 mi from Santo Tomas Station
$50 nightly
The price is $55 total per night
$55 total
Dec 27 - Dec 28
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Free self parking, a coffee shop, and a terrace are also offered.
Pool
Parking included

The Westin Playa Bonita Panama
Km 6 Road to Veracruz Veracruz Panama
Free Cancellation
Reserve now, pay when you stay
5.93 mi from Santo Tomas Station
$175 nightly
The price is $193 total per night
$193 total
Dec 19 - Dec 20
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and 4 restaurants. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. There's fun for all ages with a free kid's club and a children's pool, and families will appreciate the onsite laundry facilities.
On private beach
Pool
Don't see what you're looking for?
See all available properties in Santo Tomas Station
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santo Tomas Station hotels essential information
Accommodation | 1,599 hotels |
|---|---|
Lowest Price | $55 |
Highest Price | $272 |
Popular hotels | Hotel Riu Plaza Panama, Las Americas Golden Tower Panama, Megapolis Hotel Panamá, Waldorf Astoria Panama, Marriott Panama Hotel, Dreams Playa Bonita Panama - All Inclusive, Plaza Paitilla Inn Hotel, Principe Hotel and Suites, The Westin Playa Bonita Panama |
Recent Santo Tomas Station hotel reviews by fellow wanderers

Marriott Panama Hotel
5 out of 5
Posted 21 hours ago
Travelocity Verified Review
"This hotel accommodated my husband and I at the last minute. Due to the prior booking we had to relocate. The staff was friendly and helpful. The location was a bit further from Panama City then we would like. But we were grateful to find somewhere to stay due to it being a 3-day holiday. Would definitely stay there again. Everything you need is in this one location."
A verified traveler stayed at Marriott Panama Hotel
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