Book Cheap Hotels in Santo Tomas Station

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Top Santo Tomas Station hotels

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.99 mi from Santo Tomas Station
$122 nightly
The price is $135 total per night
$135 total
Dec 15 - Dec 16
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Pool
Breakfast included
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Free Cancellation
Reserve now, pay when you stay
1.17 mi from Santo Tomas Station
$157 nightly
The price is $175 total per night
$175 total
Dec 19 - Dec 20
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. You'll appreciate the gym, bar/lounge, and coffee shop.
Pool
Spa
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Free Cancellation
Reserve now, pay when you stay
1.07 mi from Santo Tomas Station
$131 nightly
The price is $144 total per night
$144 total
Dec 18 - Dec 19
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Pool
Hot Tub
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.59 mi from Santo Tomas Station
$180 nightly
The price is $198 total per night
$198 total
Dec 16 - Dec 17
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly dining, and babysitting. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free WiFi.
Pool
Spa
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall Panama City Panama
Free Cancellation
Reserve now, pay when you stay
1.38 mi from Santo Tomas Station
$142 nightly
The price is $156 total per night
$156 total
Dec 12 - Dec 13
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Enjoy the a rooftop terrace and visit the 2 bars/lounges and poolside bar for drinks.
Pool
Pet friendly
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Free Cancellation
Reserve now, pay when you stay
6.14 mi from Santo Tomas Station
$272 nightly
The price is $272 total per night
$272 total
Dec 19 - Dec 20
Total with taxes and fees
A full-service spa, a nightclub, and 4 outdoor pools are all featured at this all-inclusive property. Spend a day at the beach kayaking, or relax with free beach cabanas and sun loungers. There's fun for all ages with a free kid's club and mini golf, and in-room childcare is an added bonus.
Pool
Breakfast included
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
Free Cancellation
Reserve now, pay when you stay
1.14 mi from Santo Tomas Station
$108 nightly
The price is $119 total per night
$119 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Free Cancellation
Reserve now, pay when you stay
1.17 mi from Santo Tomas Station
$50 nightly
The price is $55 total per night
$55 total
Dec 27 - Dec 28
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Free self parking, a coffee shop, and a terrace are also offered.
Pool
Parking included
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5 out of 5
Km 6 Road to Veracruz Veracruz Panama
Free Cancellation
Reserve now, pay when you stay
5.93 mi from Santo Tomas Station
$175 nightly
The price is $193 total per night
$193 total
Dec 19 - Dec 20
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and 4 restaurants. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. There's fun for all ages with a free kid's club and a children's pool, and families will appreciate the onsite laundry facilities.
On private beach
Pool
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santo Tomas Station hotels essential information

Accommodation
1,599 hotels
Lowest Price
$55
Highest Price
$272
Popular hotels
Hotel Riu Plaza Panama, Las Americas Golden Tower Panama, Megapolis Hotel Panamá, Waldorf Astoria Panama, Marriott Panama Hotel, Dreams Playa Bonita Panama - All Inclusive, Plaza Paitilla Inn Hotel, Principe Hotel and Suites, The Westin Playa Bonita Panama

Recent Santo Tomas Station hotel reviews by fellow wanderers

Marriott Panama Hotel

Marriott Panama Hotel

5 out of 5
Posted 21 hours ago
Travelocity Verified Review
"This hotel accommodated my husband and I at the last minute. Due to the prior booking we had to relocate. The staff was friendly and helpful. The location was a bit further from Panama City then we would like. But we were grateful to find somewhere to stay due to it being a 3-day holiday. Would definitely stay there again. Everything you need is in this one location."
A verified traveler stayed at Marriott Panama Hotel
Marriott Panama Hotel

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