Explore 58 Luxury Hotels in Santa Maria Novella

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Best Luxury Hotels in Santa Maria Novella

The St. Regis Florence

The St. Regis Florence

Piazza Ognissanti 1 Florence FI
Fully refundableReserve now, pay when you stay
$677 nightly
The price is $763 total per night from Feb 9 to Feb 10
$763 total
Feb 9 - Feb 10
Total with taxes and fees
This hotel features a restaurant, a hot tub, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
9.6/10 Exceptional! (266 reviews)
Top notch service

Reviewed on Jan 29, 2026

Opens in a new windowThe St. Regis Florence
Hotel Santa Maria Novella

Hotel Santa Maria Novella

Piazza Santa Maria Novella 1 Florence FI
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $195 total per night from Feb 24 to Feb 25
$195 total
Feb 24 - Feb 25
Total with taxes and fees
This hotel features a gym and a rooftop terrace. Traveling for business? Take advantage of the free WiFi in public areas, express check-in, and conference space. ...
9.4/10 Exceptional! (1,000 reviews)
I love this hotel. The staff was excellent and helpful. It’s a wonderful location lovely and very convenient both to the train station and to the sites of Florence. I can’t say enough wonderful things thank you for everything.

Reviewed on Jan 20, 2026

Opens in a new windowHotel Santa Maria Novella
Hotel L'Orologio Firenze

Hotel L'Orologio Firenze

Piazza Santa Maria Novella 24 Florence FI
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $200 total per night from Feb 24 to Feb 25
$200 total
Feb 24 - Feb 25
Total with taxes and fees
This hotel features a gym and a bar/lounge. WiFi in public areas is free. Self parking, a business center, and a coffee shop are also offered.
9.4/10 Exceptional! (990 reviews)
Spotlessly clean!!! Absolutely beautiful decor. Friendly staff. Wonderful breakfast in a stunning breakfast room. Great location! Not one negative comment!!!

Reviewed on Feb 1, 2026

Opens in a new windowHotel L'Orologio Firenze
The Excelsior, a Luxury Collection Hotel, Florence

The Excelsior, a Luxury Collection Hotel, Florence

Piazza Ognissanti 3 Florence FI
Fully refundableReserve now, pay when you stay
$483 nightly
The price is $551 total per night from Feb 11 to Feb 12
$551 total
Feb 11 - Feb 12
Total with taxes and fees
The hotel's gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Enjoy a meal from the restaurant and perks like free WiFi. Valet parking, ...
9.2/10 Wonderful! (357 reviews)
Nice hotel in the heart of Firenze , friendly staff, comfortable rooms (although a bit small). The only caveat is there’s no coffee machines in the room which should be a standard in all hotels nowadays.

Reviewed on Dec 15, 2025

Opens in a new windowThe Excelsior, a Luxury Collection Hotel, Florence
Palazzo Montebello

Palazzo Montebello

Via Garibaldi, 14 Florence FI
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $201 total per night from Feb 15 to Feb 16
$201 total
Feb 15 - Feb 16
Total with taxes and fees
This hotel features a gym and a bar/lounge. WiFi in public areas is free. Self parking, a terrace, and a garden are also offered.
9/10 Wonderful! (997 reviews)
The hotel exceeded expectations. The rooms were clean, beautiful and aromatic. Upon arrival, we were upgraded to a suite, and the staff were exceptionally attentive and helpful. Thank you for a wonderful stay.

Reviewed on Jan 24, 2026

Opens in a new windowPalazzo Montebello
Sina Villa Medici, Autograph Collection

Sina Villa Medici, Autograph Collection

Via Il Prato 42 Florence FI
Fully refundableReserve now, pay when you stay
$274 nightly
The price is $320 total per night from Mar 1 to Mar 2
$320 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
8.4/10 Very Good! (311 reviews)
Staff was very helpful despite the hot weather. Great stay, very serene environment for vacation.

Reviewed on Sep 28, 2025

Opens in a new windowSina Villa Medici, Autograph Collection
Casa Howard Firenze - Residenza d'Epoca

Casa Howard Firenze - Residenza d'Epoca

18, Via della Scala Florence FI
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $171 total per night from Feb 9 to Feb 10
$171 total
Feb 9 - Feb 10
Total with taxes and fees
This property features a rooftop terrace and a bar/lounge. Guests will appreciate free perks like daily breakfast and WiFi in public areas. A terrace, a garden, ...
8.2/10 Very Good! (247 reviews)
Unique and friendly boutique hotel
We had a wonderful stay at this lovely boutique hotel within walking distance of most major museums. Casa Howard was very clean, and the breakfast-to-order served to the room every morning was extraordinary. We had 2 rooms - one with a lovely little balcony. Our room had a large bathroom with a shower. ...

Reviewed on Oct 7, 2025

Opens in a new windowCasa Howard Firenze - Residenza d'Epoca
Hotel Angelica

Hotel Angelica

Via Fiume 11 Florence FI
Free WiFi in public areas, a library, and express check-out are available at this hotel. Business travelers can take advantage of the laundry service. A computer ...
8/10 Very Good! (24 reviews)
This place is great. It is a small hotel but has everything you need for a trip. The breakfast has good variety, the room (and especially the bed) is comfortable, the hairdryer is powerful (which is not easy to find nowadays), and the staffs are super nice. Not luxury style, of course; but you get ...

Reviewed on Jan 25, 2026

Opens in a new windowHotel Angelica
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Santa Maria Novella

5 star hotels in Santa Maria Novella

Santa Maria Novella Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Santa Maria Novella luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Santa Maria Novella to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Santa Maria Novella will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Santa Maria Novella, and plan your next opulent escape.


Santa Maria Novella hotels essential information

Accommodation
775 hotels
Lowest Price
$113
Highest Price
$763
Popular hotels
Palazzo Montebello, The Excelsior, a Luxury Collection Hotel, Florence, Casa Howard Firenze - Residenza d'Epoca, Sina Villa Medici, Autograph Collection, The St. Regis Florence, Hotel Angelica, Hotel Santa Maria Novella, Hotel L'Orologio Firenze

Popular Luxury Stays in Santa Maria Novella

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