Find a Hotel in Santo Spirito

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top hotels in Santo Spirito

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
Fully refundableReserve now, pay when you stay
$292 nightly
The price is $337 total per night from Jun 7 to Jun 8
$337 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. If you want to take your pet along, this pet-friendly property offers ...
"Amazing stay! Beautiful property! The spa is a wonderful amenity."

Reviewed on May 18, 2026

Opens in a new windowHotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
Fully refundableReserve now, pay when you stay
$216 nightly
The price is $253 total per night from May 20 to May 21
$253 total
May 20 - May 21
Total with taxes and fees
Free WiFi in public areas, a library, and express check-out are available at this residence. Luggage storage and a safe deposit box are also provided.
"We were welcomed with a warm greeting and friendly smile. The person who checked us in provided us with a map and several suggestions. The room was large and comfortable. The bathroom was small, but it was fine for us. The best part was that we were only a few minutes from the wine window! All of ..."

Reviewed on May 16, 2026

Opens in a new windowPalazzo Mannaioni Suites
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
$166 nightly
The price is $199 total per night from May 24 to May 25
$199 total
May 24 - May 25
Total with taxes and fees
This residence features valet parking and free WiFi in public areas. Luggage storage and a safe deposit box are also provided.
"Staff were very welcoming and accommodated an early check in after our arrival from Rome. Hotel was centrally located, room was nice enough and exactly what we needed. Bed was comfortable, and had a few good nights sleep. Power sockets were a slight issue, having to charge my phone in the bathroom ..."

Reviewed on May 14, 2026

Opens in a new windowLa Torre Del Cestello
Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8

Via Borgo San Frediano n. 8 Florence FI
$168 nightly
The price is $201 total per night from May 24 to May 25
$201 total
May 24 - May 25
Total with taxes and fees
This bed & breakfast features valet parking and free WiFi in public areas. A terrace and luggage storage are also provided.
"Excellent place"

Reviewed on May 16, 2026

Opens in a new windowResidenza D'Epoca Al Numero 8
1900 Artevita

1900 Artevita

Viale Raffaello Sanzio 2 Florence FI
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $146 total per night from May 24 to May 25
$146 total
May 24 - May 25
Total with taxes and fees
Free WiFi in public areas is available at this bed & breakfast.
"Cute bedroom with little balcony but didn’t like how the toilet is in with the shower. It was very small and made it slippery. It’s also a bit further out of the main area. Nice tea or coffee bar whenever you want it."

Reviewed on May 13, 2026

Opens in a new window1900 Artevita
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49 Florence FI
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $147 total per night from Jun 2 to Jun 3
$147 total
Jun 2 - Jun 3
Total with taxes and fees
Free WiFi in public areas, luggage storage, and a safe deposit box are available at this guesthouse.
"Pleasant place to stay, close to Centro, with welcoming staff. Rooms, however, are not soundproof, with normal conversations in adjacent rooms easily heard."

Reviewed on May 13, 2026

Opens in a new windowForesteria Valdese di Firenze - Casa per Ferie
Casa Santo Nome di Gesù

Casa Santo Nome di Gesù

Piazza del Carmine, 21 Florence FI
Fully refundableReserve now, pay when you stay
$200 nightly
The price is $234 total per night from Jun 3 to Jun 4
$234 total
Jun 3 - Jun 4
Total with taxes and fees
This guesthouse features free WiFi in public areas, concierge services, and self parking. Enjoy the free buffet breakfast each morning. A garden, a library, ...
"The rooms were spacious and spotless! Great location as a short walk across the bridge to the centre of town and sites, but also a quiet base to come back to after a busy day. The garden area was peaceful and the breakfasts delicious. We loved our stay there."

Reviewed on May 13, 2026

Opens in a new windowCasa Santo Nome di Gesù
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
$159 nightly
The price is $191 total per night from Jun 3 to Jun 4
$191 total
Jun 3 - Jun 4
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, ...
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"

Reviewed on May 12, 2026

Opens in a new windowUNA Hotels Vittoria Firenze
Palazzo Oliveto

Palazzo Oliveto

Via Monte Oliveto Florence FI
$115 nightly
The price is $140 total per night from May 25 to May 26
$140 total
May 25 - May 26
Total with taxes and fees
Free WiFi in public areas, a garden, and luggage storage are available at this guesthouse. Enjoy the free continental breakfast each morning. A virtual front ...
"Nice and clean place, staff are friendly and helpful. It was a raining day on the second day we stay, the reception girl went out and bough an umbrella for us to use during the stay. Really appreciate it!"

Reviewed on May 11, 2026

Opens in a new windowPalazzo Oliveto
Don't see what you're looking for?
See all available properties in Santo Spirito
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santo Spirito Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Santo Spirito area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Santo Spirito to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Santo Spirito are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Santo Spirito hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity