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Top hotels in Mission District

Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
$238 nightly
The price is $280 total per night from May 31 to Jun 1
$280 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
"Very nice atmosphere inside the lobby. Staff were very attentive and helpful. Cleaning service was good and the gym also has a lot of really nice amenities and equipment. Bed was nice and the room was very clean. Overall an amazing experience and very convenient location to top it off right next ..."

Reviewed on May 29, 2026

Opens in a new windowHyatt Regency San Francisco
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $230 total per night from Jun 8 to Jun 9
$230 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"The breakfast was amazing and it was complimentary"

Reviewed on May 30, 2026

Opens in a new windowHotel Riu Plaza Fisherman's Wharf
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundable
$152 nightly
The price is $179 total per night from May 31 to Jun 1
$179 total
May 31 - Jun 1
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's ...
"Parking on site was a great benefit"

Reviewed on May 30, 2026

Opens in a new windowHoliday Inn Golden Gateway by IHG
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $164 total per night from May 31 to Jun 1
$164 total
May 31 - Jun 1
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...
"Was hoping for a nice included breakfast"

Reviewed on May 30, 2026

Opens in a new windowClub Quarters Hotel in San Francisco
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $165 total per night from Jun 6 to Jun 7
$165 total
Jun 6 - Jun 7
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...
"The staff was awesome. Check in was a breeze and the room was immaculate. The front help desk folks were knowledgeable and eager to help us find the right places to go."

Reviewed on May 30, 2026

Opens in a new windowHandlery Union Square Hotel
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $189 total per night from Jun 6 to Jun 7
$189 total
Jun 6 - Jun 7
Total with taxes and fees
The hotel's outdoor pool, 24-hour gym, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the business center and ...
"Very clean, friendly environment"

Reviewed on May 29, 2026

Opens in a new windowHilton San Francisco Union Square
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4 out of 5
55 Cyril Magnin St San Francisco CA
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $175 total per night from Jun 6 to Jun 7
$175 total
Jun 6 - Jun 7
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public ...
"Beautiful and clean hotel. The staff was fast and friendly. The beds were comfortable and the bathrooms very clean. I would definitely stay again."

Reviewed on May 29, 2026

Opens in a new windowParc 55 San Francisco - A Hilton Hotel
FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill

2 out of 5
1075 Sutter St San Francisco CA
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $127 total per night from Jun 7 to Jun 8
$127 total
Jun 7 - Jun 8
Total with taxes and fees
Free WiFi in public areas, express check-in, and express check-out are available at this hotel. Staff at the 24-hour front desk can provide around-the-clock ...
"Staff was super friendly and the decor was very nice. The room was clean and comfortable. This is an old building so there’s no real ventilation which was not the best. The other issue I had was parking, but there is a garage that’s 24 hours if you need less then 2 blocks away."

Reviewed on May 30, 2026

Opens in a new windowFOUND Hotel Carlton, Nob Hill
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $153 total per night from Jun 28 to Jun 29
$153 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. Self ...
Opens in a new windowHilton San Francisco Financial District
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mission District Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Mission District area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Mission District to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Mission District are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Mission District hotel reviews by fellow wanderers

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Parking on site was a great benefit"
A verified traveler stayed at Holiday Inn Golden Gateway by IHG
Holiday Inn Golden Gateway by IHG

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