Find a Hotel in Medical Center District
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Top hotels in Medical Center District

Hotel Valencia Riverwalk
Reviewed on Sep 25, 2025

Drury Plaza Hotel San Antonio Riverwalk
Reviewed on Sep 24, 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Reviewed on Sep 26, 2025

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Reviewed on Sep 28, 2025

Courtyard by Marriott Medical Center San Antonio
Reviewed on Sep 28, 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Reviewed on Sep 23, 2025

San Antonio Marriott Northwest Medical Center
Reviewed on Sep 27, 2025

Sonesta ES Suites San Antonio Downtown Alamo Plaza
Reviewed on Sep 23, 2025

Riverwalk Plaza
Reviewed on Sep 26, 2025
Medical Center District Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Medical Center District area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Medical Center District to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Medical Center District are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Medical Center District hotel reviews by fellow wanderers

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
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