Book Hotels in Lignumvitae Key Botanical State Park, FL
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Lignumvitae Key Botanical State Park hotels

Chesapeake Beach Resort
83409 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$247 nightly
The price is $278 total per night from Jan 27 to Jan 28
$278 total
Jan 27 - Jan 28
Total with taxes and fees
A private beach, a marina, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Unwind ...
The resort is a great family friendly atmosphere. The staff was extremely hospitable. The beach is clean and lots of fun activities to do. Only wish we had more time!
Reviewed on Jan 6, 2026

Lime Tree Bay Resort
68500 Overseas Hwy Long Key FL
$169 nightly
The price is $190 total per night from Jan 11 to Jan 12
$190 total
Jan 11 - Jan 12
Total with taxes and fees
This resort features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the outdoor ...
Great property for the price. Our first room was right next to a very noisy construction project, and smelled very strongly of cleaning liquid -- they were great about moving us to an upgraded room and we had an absolutely lovely stay other than that. If you're a strong kayaker or paddleboarder you ...
Reviewed on Jan 4, 2026

Waterside Suites & Marina
201 Ocean Drive Key Largo FL
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $188 total per night from Jan 11 to Jan 12
$188 total
Jan 11 - Jan 12
Total with taxes and fees
A marina and an outdoor pool are featured at this smoke-free hotel. WiFi in public areas is free. A terrace, a picnic area, and luggage storage are also on ...
Friendly staff, clean rooms, not far from highway, right on canal, just need to be able to handle stairs to get to upstairs bedroom/shower
Reviewed on Jan 7, 2026

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
84001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$373 nightly
The price is $419 total per night from Jan 20 to Jan 21
$419 total
Jan 20 - Jan 21
Total with taxes and fees
This Art Deco resort features a private beach, a marina, and 4 restaurants. Enjoy a day at the beach snorkeling, or relax with sun loungers. Families will appreciate ...
Amazing place - so much variety
Reviewed on Jan 6, 2026

The Pelican Key Largo Cottages
99340 Overseas Highway Key Largo FL
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $151 total per night from Jan 12 to Jan 13
$151 total
Jan 12 - Jan 13
Total with taxes and fees
This smoke-free hotel's private beach and marina are among the highlights. Guests will appreciate free perks like free self parking and WiFi in public areas. ...
Easy to check in. Loved the kayaks that were free to use.
Reviewed on Jan 3, 2026

Marina Del Mar Resort and Marina
527 Caribbean Drive Key Largo FL
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $170 total per night from Jan 14 to Jan 15
$170 total
Jan 14 - Jan 15
Total with taxes and fees
A marina, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the gym and perks like free self parking and free WiFi. You'll ...
Amazing
Reviewed on Jan 7, 2026

Baker's Cay Resort Key Largo, Curio Collection by Hilton
97000 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
$459 nightly
The price is $516 total per night from Jan 22 to Jan 23
$516 total
Jan 22 - Jan 23
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
The only negative things about this hotel was the quality of food. The breakfast was pricey and not good at all.
Reviewed on Jan 5, 2026

Holiday Inn Key Largo by IHG
99701 Overseas Hwy Key Largo FL
Fully refundable
$189 nightly
The price is $213 total per night from Jan 11 to Jan 12
$213 total
Jan 11 - Jan 12
Total with taxes and fees
A marina, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Relax with a drink at one of the 2 bars/lounges and enjoy free perks ...
very good
Reviewed on Jan 6, 2026

Hawks Cay Resort
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$343 nightly
The price is $384 total per night from Jan 29 to Jan 30
$384 total
Jan 29 - Jan 30
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
Overall a great stay. Very nice and clean condo with its own small pool. The property is beautiful and we enjoyed the tennis and pickleball facilities. Only areas for improvement were the initial delay in room being available from housekeeping and need for more service staff around the pool ...
Reviewed on Jan 4, 2026
Don't see what you're looking for?
See all available properties in Lignumvitae Key Botanical State Park
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Lignumvitae Key Botanical State Park with star-rating
Check Lignumvitae Key Botanical State Park Hotels by Star Rating

5 Star Hotels
3 properties
Explore More Ways to Travel with Travelocity
- Matecumbe Hotels
- Hotels near Bud n' Mary's Dive Center
- Plantation Key Hotels
- Venetian Shores Hotels
- Hotels near Bluefin Rock Harbor Marina
- Hotels near Florida Keys Dive Center
- Hotels near Windley Key Fossil Reef Geological State Park
- Hotels near Baker's Cay Resort Beach
- Wynken Blynken and Nod Hotels
- Hotels near Founders Park
- Long Key Hotels
- Layton Hotels
- Key Largo Hotels
- Hotels near Long Key State Park
- Hotels near Florida Keys Brewing Co.
- Duck Key Hotels
- Hotels near Anne's Beach
- 4 Star Hotels in Islamorada
- 5 Star Hotels in Islamorada
- Apartments in Islamorada
- B&B in Islamorada
- Condo Resorts in Islamorada
- Condos in Islamorada
- Cottages in Islamorada
- Extended Stay Hotels in Islamorada
- Guest Houses in Islamorada
- Adults Only Resorts & in Islamorada
- All Inclusive Resorts & in Islamorada
- Beach Resorts & in Islamorada
- Boutique Hotels in Islamorada
- Casino Resorts & in Islamorada
- Cheap Hotels in Islamorada
- Kid Friendly Hotels in Islamorada
- Gay Friendly Hotels in Islamorada
- Golf Resorts & in Islamorada
- Hilton Hotels in Islamorada
- Historic Hotels in Islamorada
- Hotels with Pools in Islamorada
- Hotels with Bar in Islamorada
- Hotels with Free Breakfast in Islamorada
- Hotels with a Gym in Islamorada
- Hotels with Free Parking in Islamorada
- Hotels with Hot Tubs in Islamorada
- Hotels with smoking rooms in Islamorada
- Luxury Hotels in Islamorada
- Oceanfront Hotels in Islamorada
- Pet Friendly Hotels in Islamorada
- Romantic Getaways & Hotels in Islamorada
- Spa Resorts & in Islamorada
- Wyndham Hotels in Islamorada
- Islamorada Hotels
- Houseboats in Islamorada
- Lodges in Islamorada
- Motels in Islamorada
- Vacation Homes in Islamorada
- Rv Parks in Islamorada
- Resorts in Islamorada
- Villas in Islamorada
- Hotels near Sunset Drive Beach
- Grassy Key Hotels
- 2 Star Hotels in Lower Matecumbe Key
- 4 Star Hotels in Lower Matecumbe Key
- Apartments in Lower Matecumbe Key
- Condos in Lower Matecumbe Key
- Aimbridge Hospitality Hotels in Lower Matecumbe Key
- Lower Matecumbe Key Hotels
- Houseboats in Lower Matecumbe Key
- Hotels near Fiesta Key
- Hotels near Harry Harris Park
- Buccaneer Point Hotels
- Tavernier Hotels
- Lower Matecumbe Beach Hotels
- 4 Star Hotels in Upper Matecumbe Key
- Extended Stay Hotels in Upper Matecumbe Key
- Holiday Park Resorts in Upper Matecumbe Key
- Aimbridge Hospitality Hotels in Upper Matecumbe Key
- Beach Resorts & in Upper Matecumbe Key
- Hotels with Pools in Upper Matecumbe Key
- Hotels near Pigeon Key
- Hotels near Matecumbe United Methodist Church
- Conch Key Hotels
- Hotels near Jimmy Johnson's Big Chill
- Flights to Islamorada
- Flights from Atlanta to Islamorada
- Flights from Dallas to Islamorada
- Flights from New York to Islamorada
- Flights from Orlando to Islamorada
- Flights from Philadelphia to Islamorada
- Flights from Phoenix to Islamorada
- Flights from Newark to Islamorada
- Flights to Lower Matecumbe Key
- Oceanfront Hotels in Islamorada
- Resorts in Islamorada
- Cheap Hotels in Islamorada
- Flights to Islamorada
- Motels in Islamorada
- Beach Hotels in Islamorada
- Pet-friendly Hotels in Islamorada
- Islamorada vacations
- Houseboats in Islamorada
- Hotels in Islamorada
- Islamorada vacation rentals
- Luxury Hotels in Islamorada
- Cottages in Islamorada




