Book a hotel near Lignumvitae Key Botanical State Park, Islamorada

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Hotels near Lignumvitae Key Botanical State Park

Chesapeake Beach Resort

Chesapeake Beach Resort

3.5 out of 5
83409 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$305 nightly
The price is $344 total per night from Feb 11 to Feb 12
$344 total
Feb 11 - Feb 12
Total with taxes and fees
A private beach, a marina, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Unwind ...
We loved this place. It’s small and easy to get around. Beautiful setting, watched the sunrise from bed, and the best hotel breakfast we’ve ever had.

Reviewed on Feb 3, 2026

Opens in a new windowChesapeake Beach Resort
Cheeca Lodge & Spa

Cheeca Lodge & Spa

5 out of 5
81801 Overseas Highway, Mile Marker 82 Islamorada FL
Fully refundableReserve now, pay when you stay
$440 nightly
The price is $496 total per night from Feb 10 to Feb 11
$496 total
Feb 10 - Feb 11
Total with taxes and fees
This luxury resort features a private beach, a golf course, and a full-service spa. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
Paradise away from Home!! Thank you!

Reviewed on Feb 7, 2026

Opens in a new windowCheeca Lodge & Spa
Lime Tree Bay Resort

Lime Tree Bay Resort

3.5 out of 5
68500 Overseas Hwy Long Key FL
$262 nightly
The price is $295 total per night from Feb 10 to Feb 11
$295 total
Feb 10 - Feb 11
Total with taxes and fees
This resort features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the outdoor ...
All the above

Reviewed on Feb 6, 2026

Opens in a new windowLime Tree Bay Resort
Waterside Suites & Marina

Waterside Suites & Marina

3.5 out of 5
201 Ocean Drive Key Largo FL
Fully refundableReserve now, pay when you stay
$224 nightly
The price is $253 total per night from Feb 12 to Feb 13
$253 total
Feb 12 - Feb 13
Total with taxes and fees
A marina and an outdoor pool are featured at this smoke-free hotel. WiFi in public areas is free. A terrace, a picnic area, and luggage storage are also on ...
The room was nice with sitting area downstairs and bedroom upstairs. Lots of room with a kitchen and balcony.

Reviewed on Feb 6, 2026

Opens in a new windowWaterside Suites & Marina
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

2.5 out of 5
527 Caribbean Drive Key Largo FL
Fully refundableReserve now, pay when you stay
$205 nightly
The price is $231 total per night from Feb 12 to Feb 13
$231 total
Feb 12 - Feb 13
Total with taxes and fees
A marina, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the gym and perks like free self parking and free WiFi. You'll ...
The rooms, the bathrooms, the pool area, threception area, etc. were so so clean. Staff were wonderful, helpful, and kind. We would stay there again!!! Id only suggest that they get toasters for the rooms with kitchens, and for breakfast.

Reviewed on Feb 6, 2026

Opens in a new windowMarina Del Mar Resort and Marina
Bayside Inn Key Largo

Bayside Inn Key Largo

3 out of 5
99490 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
$234 nightly
The price is $260 total per night from Feb 9 to Feb 10
$260 total
Feb 9 - Feb 10
Total with taxes and fees
A private beach, a 24-hour gym, and a restaurant are all featured at this hotel. Enjoy a day at the beach snorkeling, or relax with sun loungers. Business travelers ...
Best little place ever, free bicycles and kayaks and coffee! Perfect spot to stay the night!

Reviewed on Feb 3, 2026

Opens in a new windowBayside Inn Key Largo
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4 out of 5
97000 Overseas Hwy Key Largo FL
$569 nightly
The price is $640 total per night from Feb 9 to Feb 10
$640 total
Feb 9 - Feb 10
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
Loved the beach and the included beach activies

Reviewed on Feb 2, 2026

Opens in a new windowBaker's Cay Resort Key Largo, Curio Collection by Hilton
Ocean Pointe Suites at Key Largo

Ocean Pointe Suites at Key Largo

3.5 out of 5
500 Burton Dr Tavernier FL
$299 nightly
The price is $335 total per night from Mar 2 to Mar 3
$335 total
Mar 2 - Mar 3
Total with taxes and fees
This smoke-free hotel features a private beach, 2 outdoor tennis courts, and a restaurant. Relax with a drink at one of the 2 bars/lounges and get perks like ...
Clean and comfortable

Reviewed on Feb 6, 2026

Opens in a new windowOcean Pointe Suites at Key Largo
Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$452 nightly
The price is $508 total per night from Feb 11 to Feb 12
$508 total
Feb 11 - Feb 12
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
Great atmosphe

Reviewed on Jan 27, 2026

Opens in a new windowHawks Cay Resort
Don't see what you're looking for?
See all available properties in Lignumvitae Key Botanical State Park
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Lignumvitae Key Botanical State Park hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity