Book Hotels in Lignumvitae Key Botanical State Park, FL

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Lignumvitae Key Botanical State Park hotels

Chesapeake Beach Resort

Chesapeake Beach Resort

3.5 out of 5
83409 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$275 nightly
The price is $310 total per night from Jan 26 to Jan 27
$310 total
Jan 26 - Jan 27
Total with taxes and fees
A private beach, a marina, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Unwind ...
Room was clean. Check in was fast and the staff was very friendly and welcoming.

Reviewed on Jan 18, 2026

Opens in a new windowChesapeake Beach Resort
Lime Tree Bay Resort

Lime Tree Bay Resort

3.5 out of 5
68500 Overseas Hwy Long Key FL
$229 nightly
The price is $258 total per night from Jan 29 to Jan 30
$258 total
Jan 29 - Jan 30
Total with taxes and fees
This resort features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the outdoor ...
The staff and property are fantastic. Can’t wait to come back.

Reviewed on Jan 19, 2026

Opens in a new windowLime Tree Bay Resort
Cheeca Lodge & Spa

Cheeca Lodge & Spa

5 out of 5
81801 Overseas Highway, Mile Marker 82 Islamorada FL
Fully refundableReserve now, pay when you stay
$346 nightly
The price is $390 total per night from Jan 29 to Jan 30
$390 total
Jan 29 - Jan 30
Total with taxes and fees
This luxury resort features a private beach, a golf course, and a full-service spa. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
Nice resort

Reviewed on Jan 19, 2026

Opens in a new windowCheeca Lodge & Spa
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

3.5 out of 5
84001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$398 nightly
The price is $448 total per night from Jan 29 to Jan 30
$448 total
Jan 29 - Jan 30
Total with taxes and fees
This Art Deco resort features a private beach, a marina, and 4 restaurants. Enjoy a day at the beach snorkeling, or relax with sun loungers. Families will appreciate ...
All staff members were great!

Reviewed on Jan 16, 2026

Opens in a new windowThree Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Waterside Suites & Marina

Waterside Suites & Marina

3.5 out of 5
201 Ocean Drive Key Largo FL
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $217 total per night from Jan 25 to Jan 26
$217 total
Jan 25 - Jan 26
Total with taxes and fees
A marina and an outdoor pool are featured at this smoke-free hotel. WiFi in public areas is free. A terrace, a picnic area, and luggage storage are also on ...
Loved the King suite and the BBQ area. Really nice place and the staff is great! They were able to give recommendations of things to do and beaches to go to. Will definitely stay here again

Reviewed on Jan 20, 2026

Opens in a new windowWaterside Suites & Marina
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4 out of 5
97000 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
$402 nightly
The price is $452 total per night from Feb 3 to Feb 4
$452 total
Feb 3 - Feb 4
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
Beautiful balcony. Tres and beach. Secluded feel

Reviewed on Jan 17, 2026

Opens in a new windowBaker's Cay Resort Key Largo, Curio Collection by Hilton
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

2.5 out of 5
527 Caribbean Drive Key Largo FL
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $188 total per night from Jan 26 to Jan 27
$188 total
Jan 26 - Jan 27
Total with taxes and fees
A marina, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the gym and perks like free self parking and free WiFi. You'll ...
My husband and I and my sister and her husband enjoyed a 2 night stay here. The hotel is old but the rooms are extremely spacious and spotless. The beds are super comfortable and they have wonderful pillows and the sheets are crisp. There was a complimentary breakfast in the mornings for convience ...

Reviewed on Jan 17, 2026

Opens in a new windowMarina Del Mar Resort and Marina
Ocean Pointe Suites at Key Largo

Ocean Pointe Suites at Key Largo

3.5 out of 5
500 Burton Dr Tavernier FL
$201 nightly
The price is $224 total per night from Feb 1 to Feb 2
$224 total
Feb 1 - Feb 2
Total with taxes and fees
This smoke-free hotel features a private beach, 2 outdoor tennis courts, and a restaurant. Relax with a drink at one of the 2 bars/lounges and get perks like ...
Condo was spotless. Staff was friendly and helpful. Great location. Easy access to Highway 1.

Reviewed on Jan 21, 2026

Opens in a new windowOcean Pointe Suites at Key Largo
Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$377 nightly
The price is $423 total per night from Feb 1 to Feb 2
$423 total
Feb 1 - Feb 2
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
Beautiful place

Reviewed on Jan 14, 2026

Opens in a new windowHawks Cay Resort
Don't see what you're looking for?
See all available properties in Lignumvitae Key Botanical State Park
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Lignumvitae Key Botanical State Park hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity