Book Hotels in Lignumvitae Key Botanical State Park, FL

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Lignumvitae Key Botanical State Park hotels

Chesapeake Beach Resort

Chesapeake Beach Resort

3.5 out of 5
83409 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$247 nightly
The price is $278 total per night from Jan 27 to Jan 28
$278 total
Jan 27 - Jan 28
Total with taxes and fees
A private beach, a marina, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Unwind ...
The resort is a great family friendly atmosphere. The staff was extremely hospitable. The beach is clean and lots of fun activities to do. Only wish we had more time!

Reviewed on Jan 6, 2026

Opens in a new windowChesapeake Beach Resort
Lime Tree Bay Resort

Lime Tree Bay Resort

3.5 out of 5
68500 Overseas Hwy Long Key FL
$169 nightly
The price is $190 total per night from Jan 11 to Jan 12
$190 total
Jan 11 - Jan 12
Total with taxes and fees
This resort features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the outdoor ...
Great property for the price. Our first room was right next to a very noisy construction project, and smelled very strongly of cleaning liquid -- they were great about moving us to an upgraded room and we had an absolutely lovely stay other than that. If you're a strong kayaker or paddleboarder you ...

Reviewed on Jan 4, 2026

Opens in a new windowLime Tree Bay Resort
Waterside Suites & Marina

Waterside Suites & Marina

3.5 out of 5
201 Ocean Drive Key Largo FL
Fully refundableReserve now, pay when you stay
$167 nightly
The price is $188 total per night from Jan 11 to Jan 12
$188 total
Jan 11 - Jan 12
Total with taxes and fees
A marina and an outdoor pool are featured at this smoke-free hotel. WiFi in public areas is free. A terrace, a picnic area, and luggage storage are also on ...
Friendly staff, clean rooms, not far from highway, right on canal, just need to be able to handle stairs to get to upstairs bedroom/shower

Reviewed on Jan 7, 2026

Opens in a new windowWaterside Suites & Marina
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

3.5 out of 5
84001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$373 nightly
The price is $419 total per night from Jan 20 to Jan 21
$419 total
Jan 20 - Jan 21
Total with taxes and fees
This Art Deco resort features a private beach, a marina, and 4 restaurants. Enjoy a day at the beach snorkeling, or relax with sun loungers. Families will appreciate ...
Amazing place - so much variety

Reviewed on Jan 6, 2026

Opens in a new windowThree Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

2 out of 5
99340 Overseas Highway Key Largo FL
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $151 total per night from Jan 12 to Jan 13
$151 total
Jan 12 - Jan 13
Total with taxes and fees
This smoke-free hotel's private beach and marina are among the highlights. Guests will appreciate free perks like free self parking and WiFi in public areas. ...
Easy to check in. Loved the kayaks that were free to use.

Reviewed on Jan 3, 2026

Opens in a new windowThe Pelican Key Largo Cottages
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

2.5 out of 5
527 Caribbean Drive Key Largo FL
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $170 total per night from Jan 14 to Jan 15
$170 total
Jan 14 - Jan 15
Total with taxes and fees
A marina, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the gym and perks like free self parking and free WiFi. You'll ...
Amazing

Reviewed on Jan 7, 2026

Opens in a new windowMarina Del Mar Resort and Marina
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4 out of 5
97000 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
$459 nightly
The price is $516 total per night from Jan 22 to Jan 23
$516 total
Jan 22 - Jan 23
Total with taxes and fees
A private beach, 2 restaurants, and 2 outdoor pools are all featured at this resort. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
The only negative things about this hotel was the quality of food. The breakfast was pricey and not good at all.

Reviewed on Jan 5, 2026

Opens in a new windowBaker's Cay Resort Key Largo, Curio Collection by Hilton
Holiday Inn Key Largo by IHG

Holiday Inn Key Largo by IHG

3 out of 5
99701 Overseas Hwy Key Largo FL
Fully refundable
$189 nightly
The price is $213 total per night from Jan 11 to Jan 12
$213 total
Jan 11 - Jan 12
Total with taxes and fees
A marina, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Relax with a drink at one of the 2 bars/lounges and enjoy free perks ...
very good

Reviewed on Jan 6, 2026

Opens in a new windowHoliday Inn Key Largo by IHG
Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$343 nightly
The price is $384 total per night from Jan 29 to Jan 30
$384 total
Jan 29 - Jan 30
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
Overall a great stay. Very nice and clean condo with its own small pool. The property is beautiful and we enjoyed the tennis and pickleball facilities. Only areas for improvement were the initial delay in room being available from housekeeping and need for more service staff around the pool ...

Reviewed on Jan 4, 2026

Opens in a new windowHawks Cay Resort
Don't see what you're looking for?
See all available properties in Lignumvitae Key Botanical State Park
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Explore More Ways to Travel with Travelocity