Find a Hotel in Isle of Palms South

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top hotels in Isle of Palms South

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $169 total per night from Feb 2 to Feb 3
$169 total
Feb 2 - Feb 3
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
I had a particle ocean view it was a great room. Also, the bartender near the pool were awesome

Reviewed on Jan 27, 2026

Opens in a new windowMargaritaville Jacksonville Beach
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr Jacksonville FL
$214 nightly
The price is $243 total per night from Feb 9 to Feb 10
$243 total
Feb 9 - Feb 10
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
Yes great room , really clean

Reviewed on Jan 31, 2026

Opens in a new windowHyatt Regency Jacksonville
Best Western Oceanfront

Best Western Oceanfront

3 out of 5
305 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $143 total per night from Feb 2 to Feb 3
$143 total
Feb 2 - Feb 3
Total with taxes and fees
An outdoor pool, self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like full breakfast and WiFi in public areas. ...
Loved the location of this hotel! Right next to the beach. The staff was great, and I loved the fresh cookies every night. Only thing not great was a low-pressure, lukewarm shower.

Reviewed on Jan 25, 2026

Opens in a new windowBest Western Oceanfront
The Villas of Amelia Island

The Villas of Amelia Island

4 out of 5
8 Amelia Village Circle, Amelia Island Fernandina Beach FL
Fully refundableReserve now, pay when you stay
$209 nightly
The price is $234 total per night from Feb 27 to Feb 28
$234 total
Feb 27 - Feb 28
Total with taxes and fees
This smoke-free vacation home features a golf course, a full-service spa, and 9 restaurants. Enjoy a day at the beach kayaking, or relax with beach cabanas. ...
Beautiful grounds, very helpful staff, great amenities. Cedric the tram driver was the highlight of our trip! Great stories, helpful suggestions about where to eat and such a pleasant perspective! The shops are wonderful with unique clothing and accessories.

Reviewed on Jan 14, 2026

Opens in a new windowThe Villas of Amelia Island
San Marco Inn East

San Marco Inn East

3 out of 5
3558 Phillips Hwy Jacksonville FL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $74 total per night from Feb 3 to Feb 4
$74 total
Feb 3 - Feb 4
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, dry cleaning, and laundry facilities are also on offer.
New and Clean Rooms !

Reviewed on Jan 27, 2026

Opens in a new windowSan Marco Inn East
Southbank Hotel by Marriott Jacksonville Riverwalk

Southbank Hotel by Marriott Jacksonville Riverwalk

3.5 out of 5
1515 Prudential Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $132 total per night from Feb 22 to Feb 23
$132 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
Excellent place to stay.

Reviewed on Jan 28, 2026

Opens in a new windowSouthbank Hotel by Marriott Jacksonville Riverwalk
Comfort Suites Baymeadows Near Butler Blvd

Comfort Suites Baymeadows Near Butler Blvd

3 out of 5
8277 Western Way Cir Jacksonville FL
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $110 total per night from Feb 5 to Feb 6
$110 total
Feb 5 - Feb 6
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
For the price. It was good. Breakfast was basic but included. The room was fairly clean and no weird smells. Front desk staff was nice.

Reviewed on Jan 30, 2026

Opens in a new windowComfort Suites Baymeadows Near Butler Blvd
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road Jacksonville FL
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $84 total per night from Feb 15 to Feb 16
$84 total
Feb 15 - Feb 16
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
everything was good

Reviewed on Jan 28, 2026

Opens in a new windowWyndham Garden Jacksonville
DoubleTree by Hilton Hotel Jacksonville Riverfront

DoubleTree by Hilton Hotel Jacksonville Riverfront

4 out of 5
1201 Riverplace Boulevard Jacksonville FL
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $163 total per night from Feb 8 to Feb 9
$163 total
Feb 8 - Feb 9
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi. ...
Parking is very expensive. My 1st room had no refrigerator or microwave, but they made it up with my 2nd beautiful room. There were stains in the carpet and a mess in the elevator but the views and space is amazing depending on the room you get.

Reviewed on Jan 27, 2026

Opens in a new windowDoubleTree by Hilton Hotel Jacksonville Riverfront
Don't see what you're looking for?
See all available properties in Isle of Palms South
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Isle of Palms South Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Isle of Palms South area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Isle of Palms South to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Isle of Palms South are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Isle of Palms South hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity