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Top hotels in Grand Isle

Driftwood Inn
Everything was wonderful! The inn is clean and very pet friendly.
Reviewed on May 4, 2026

Waterfront on N. CSB, Dog-friendly, Amazing Views!
Very clean with plenty of towels! Loved the upper and lower decks - especially the loungers on the upper and the swing on the lower. The kitchen basics were there but coffee filters and a starter pack of coffee would have been appreciated our first morning. A great trip and we will definitely try ...
Reviewed on Apr 26, 2026

Candlewood Suites Panama City Tyndall AFB by IHG
Very nice room comfortable bed. If only you serve breakfast, you would be excellent.
Reviewed on May 3, 2026

Oceanfront Sand Between Your Toes!
Beautiful place to stay on a beautiful and quiet beach. We will definitely be back! We had a couple of minor issues when checking in but Norman was very responsive and helpful. I highly recommend Mexico Beach and this VRBO rental for a quiet vacation. The house had everything we needed and is in ...
Reviewed on Apr 23, 2026

Comfort Suites
Clean room, good staff. Quick check in
Reviewed on Apr 26, 2026

MainStay Suites Port Saint Joe South
We loved staying here. It was quiet and clean and had a kitchenette for us to make some quiet dinners. Perfect launching place to enjoy the area.
Reviewed on Apr 25, 2026

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
As expected.
Reviewed on May 3, 2026

Days Inn by Wyndham Panama City/Callaway
The room had a smell like mold , termites were flying everywhere. The staff was rude and the pool was down.
Reviewed on May 4, 2026

Extended Stay America Select Suites - Panama City - Callaway
There was only a bar soap in the shower . Very noisy and the room had the window open when I got there I couldn’t reach to close the blinds. They were open on the second floor.
Reviewed on May 2, 2026
Grand Isle Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Grand Isle area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Grand Isle to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Grand Isle are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Grand Isle hotel reviews by fellow wanderers

Driftwood Inn
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