Book Guest Houses in Defiance, MO

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Top Guest Houses in Defiance

The Inn at Elijah McLeans

602 W Front St Washington MO

Free Cancellation

Reserve now, pay when you stay

$144 nightly

$164 total

Jun 9 - Jun 10

Total with taxes and fees

This guesthouse doesn't skimp on freebies - guests receive free WiFi and free self parking. A bar/lounge is also provided.

Spacious home in Historic St. Charles, Near Main Street + self-serve breakfast

St Charles MO

Get rates

This guesthouse includes a garden and laundry facilities. Free self-serve breakfast is served.

Don't see what you're looking for?

See all available properties in Defiance

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top hotels in Defiance

Drury Inn & Suites Southwest St. Louis

5 Lambert Drury Place (I-44 & 141) Valley Park MO

$128 nightly

$150 total

Jul 5 - Jul 6

Total with taxes and fees

9.6/10 Exceptional! (1,008 reviews)

Defiance Guest Houses essential information

Accommodation	1 Guest Houses
Lowest Price	$87
Highest Price	$226
Popular accommodation	The Inn at Elijah McLeans, Spacious home in Historic St. Charles, Near Main Street + self-serve breakfast