Book Hotels in Daufuskie Island, SC
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Daufuskie Island hotels

River Street Inn
124 E. Bay Street Savannah GA
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $199 total per night from Jul 1 to Jul 2
$199 total
Jul 1 - Jul 2
Total with taxes and fees
This luxury hotel's 3 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. WiFi in public areas is free. Valet parking, a coffee ...
"Always the best stay! The generous Manager’s reception makes this place stand out!"
Reviewed on Jun 14, 2026

Hyatt Regency Savannah
2 W Bay St Savannah GA
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $159 total per night from Jun 18 to Jun 19
$159 total
Jun 18 - Jun 19
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"Room war very clean! Staff was very nice and helpful. Breakfast was great."
Reviewed on Jun 14, 2026

Palmera Inn and Suites
12 Park Ln Hilton Head Island SC
Fully refundableReserve now, pay when you stay
$195 nightly
The price is $212 total per night from Jun 15 to Jun 16
$212 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Enjoy the hot tub and free on-the-go breakfast each morning. A business center, a terrace, and a garden ...
"Nice pool and spa!! Clean room! Helpful staff!!"
Reviewed on Jun 14, 2026

Beach House Resort Hilton Head
1 South Forest Beach Drive Hilton Head Island SC
Fully refundableReserve now, pay when you stay
$297 nightly
The price is $327 total per night from Jul 1 to Jul 2
$327 total
Jul 1 - Jul 2
Total with taxes and fees
This hotel features 2 bars/lounges, a beach bar, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The resort had a location that can't be beat, near the center of the island and walkable to restaurants, shopping, and the beach. It was clean but worn (most hotels along the water will be). It's hard to keep the humidity out but the room gave it a darn good try. We fell for the upsell of renting ..."
Reviewed on Jun 13, 2026

The DeSoto
15 East Liberty Street Savannah GA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $200 total per night from Jun 29 to Jun 30
$200 total
Jun 29 - Jun 30
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
"The location is great and the staff were amazing. On the downside, no refrigerator in the room."
Reviewed on Jun 13, 2026

Sonesta Resort Hilton Head Island
130 Shipyard Drive Hilton Head Island SC
Fully refundableReserve now, pay when you stay
$341 nightly
The price is $375 total per night from Jun 21 to Jun 22
$375 total
Jun 21 - Jun 22
Total with taxes and fees
A full-service spa, 5 restaurants, and 2 outdoor pools are all featured at this smoke-free hotel. Families will appreciate the children's club and onsite laundry ...
"We had such a wonderful stay at Sonesta Resort Hilton Head Island! We’ve been coming to Hilton Head for over 20 years. We’ve stayed all over the island but really love Sonesta.The property itself is absolutely beautiful and so well maintained. From the gorgeous grounds to the spa-like adult pool ..."
Reviewed on Jun 12, 2026

Hilton Beachfront Resort & Spa Hilton Head Island
1 Hotel Circle Hilton Head Island SC
Fully refundableReserve now, pay when you stay
$332 nightly
The price is $366 total per night from Jul 7 to Jul 8
$366 total
Jul 7 - Jul 8
Total with taxes and fees
A full-service spa, 5 restaurants, and 2 outdoor pools are all featured at this luxury resort. Dine at the beachfront restaurant and relax with beach umbrellas. ...
"Awesome stay Nice and clean"
Reviewed on Jun 13, 2026

Holiday Inn Express Hilton Head Island by IHG
10 Tanglewood Drive Hilton Head Island SC
Fully refundableReserve now, pay when you stay
$172 nightly
The price is $189 total per night from Jul 1 to Jul 2
$189 total
Jul 1 - Jul 2
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Clean, comfy room walking distance from everything we wanted to do. Staff was very sweet. I was confused by the listing on here saying, "Free buffet breakfast on weekend mornings"--we were only here M-F, and there was a nice free breakfast every day."
Reviewed on Jun 12, 2026

Hotel Indigo Savannah Historic District by IHG
201 W Bay St Savannah GA
Fully refundable
$130 nightly
The price is $156 total per night from Jul 5 to Jul 6
$156 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Spacious clean rooms and helpful and friendly staff. Location is premium next to all the restaurants and shopping."
Reviewed on Jun 13, 2026
Don't see what you're looking for?
See all available properties in Daufuskie Island
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Daufuskie Island with star-rating
Check Daufuskie Island Hotels by Star Rating

3 Star Hotels
2254 properties
Frequently asked questions
Recent Daufuskie Island hotel reviews by fellow wanderers

River Street Inn
5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"Always the best stay! The generous Manager’s reception makes this place stand out!"
A verified traveler stayed at River Street Inn
Explore More Ways to Travel with Travelocity
- Hotels near Harbour Town Golf Links
- Hotels near Coligny Beach
- Bluffton Hotels
- Beach Resorts & in Oceanside
- Boutique Hotels in Oceanside
- Golf Resorts & in Oceanside
- Luxury Hotels in Oceanside
- Oceanside Hotels
- 5 Star Hotels in Palmetto Bluff
- Boutique Hotels in Palmetto Bluff
- Ski Resorts and in Palmetto Bluff
- Palmetto Bluff Hotels
- Boutique Hotels in Harbour Town
- Cheap Hotels in Harbour Town
- Golf Resorts & in Harbour Town
- Historic Hotels in Harbour Town
- Hotels with Free Parking in Harbour Town
- Hotels with Hot Tubs in Harbour Town
- Pet Friendly Hotels in Harbour Town
- Spa Resorts & in Harbour Town
- Hotels near The Village at Wexford
- Hotels near Hilton Head Zipline
- Beach Resorts & in South Forest Beach
- Luxury Hotels in South Forest Beach
- South Forest Beach Hotels
- Hotels near Coligny Theater
- Hotels near Newhall Audubon Preserve
- Hotels near Heyward House Historic Center
- Hotels near May River Golf Club at Palmetto Bluff
- Hotels near Atlantic Dunes by Davis Love III
- Hotels near Coligny Plaza
- Heritage Woods Hotels
- Hotels near Sea Pines Forest Preserve
- Hotels near Heron Point by Pete Dye
- Beach Resorts & in Melrose on the Beach
- Hotels with Pools in Melrose on the Beach
- Melrose on the Beach Hotels
- Beach Resorts & in South Beach
- South Beach Hotels
- Hotels near The Sandbox
- Hotels near Van Der Meer Tennis Center
- 4 Star Hotels in Hilton Head Island
- Apartments in Hilton Head Island
- Cabins in Hilton Head Island
- Condos in Hilton Head Island
- Cottages in Hilton Head Island
- Extended Stay Hotels in Hilton Head Island
- All Inclusive Resorts & in Hilton Head Island
- Beach Resorts & in Hilton Head Island
- Convention Center Hotels in Hilton Head Island
- Kid Friendly Hotels in Hilton Head Island
- Golf Resorts & in Hilton Head Island
- Hotels with a Lazy River in Hilton Head Island
- Hotels with Hot Tubs in Hilton Head Island
- Hotels with an Indoor Pool in Hilton Head Island
- Hotels with smoking rooms in Hilton Head Island
- Hotels with Waterslides in Hilton Head Island
- Oceanfront Hotels in Hilton Head Island
- Pet Friendly Hotels in Hilton Head Island
- Romantic Getaways & Hotels in Hilton Head Island
- Ski Resorts and in Hilton Head Island
- Spa Resorts & in Hilton Head Island
- Wyndham Hotels in Hilton Head Island
- Hilton Head Island Hotels
- Houseboats in Hilton Head Island
- Motels in Hilton Head Island
- Vacation Homes in Hilton Head Island
- Resorts in Hilton Head Island
- Villas in Hilton Head Island
- Beach Resorts & in Sea Pines
- Cheap Hotels in Sea Pines
- Convention Center Hotels in Sea Pines
- Golf Resorts & in Sea Pines
- Hotels with Pools in Sea Pines
- Luxury Hotels in Sea Pines
- Ski Resorts and in Sea Pines
- Sea Pines Hotels
- Hotels near Heron Point by Pete Dye at Sea Pines Resort
- Beach Resorts & in Beach Lagoon
- Beach Lagoon Hotels
- Hotels near Harbour Town Lighthouse
- Hotels near Van Der Meer Tennis Academy
- Hotels near Tybee National Wildlife Refuge
- Hotels near Shipyard Golf Course
- North Forest Beach Hotels
- 5 Star Hotels in Hilton Head Island
- Condos in Hilton Head Island
- Hotels in Hilton Head Island
- Cheap Hotels in Hilton Head Island
- All-inclusive Resorts in Hilton Head Island
- Flights to Hilton Head Island
- Hotels with an Indoor Pool in Hilton Head Island
- Luxury Hotels in Hilton Head Island
- Hotels near Harbour Town Lighthouse
- Oceanfront Hotels in Hilton Head Island
- Pet-friendly Hotels in Hilton Head Island
- Hotels in Bluffton
- Villas in Hilton Head Island
- Hotels in Daufuskie Island
- Hilton Head Island vacations
- Car rentals in Hilton Head Island
- Hilton Head Island vacation rentals
- Hotels in Sea Pines
- Family Hotels in Hilton Head Island
- Hotels near Coligny Plaza






