Book Hotels in Casco Bay Islands, ME

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Top Casco Bay Islands hotels

Portland Harbor Hotel

Portland Harbor Hotel

4 out of 5
468 Fore Street Portland ME
Fully refundableReserve now, pay when you stay
$349 nightly
The price is $386 total per night from Jul 5 to Jul 6
$386 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features 3 coffee shops/cafes and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"Iron broken. Construction outside."

Reviewed on Jun 26, 2026

Opens in a new windowPortland Harbor Hotel
Cambria Hotel Portland Downtown-Old Port

Cambria Hotel Portland Downtown-Old Port

3 out of 5
25 HANCOCK STREET Portland ME
Fully refundable
$261 nightly
The price is $289 total per night from Jul 5 to Jul 6
$289 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"The size of the room and proximity to Old Town were good. However, the view was to the office building next door and our room did not get cleaned while we were there for 2 nights. The room and average breakfast were too expensive for what we got."

Reviewed on Jun 27, 2026

Opens in a new windowCambria Hotel Portland Downtown-Old Port
Portland Regency Hotel & Spa

Portland Regency Hotel & Spa

3.5 out of 5
20 Milk Street Portland ME
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $282 total per night from Jul 5 to Jul 6
$282 total
Jul 5 - Jul 6
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Unwind with a drink at one of the 2 bars/lounges and enjoy freebies ...
"Lovely place to stay by everything. Beautiful old building with some charm. Bar is swanky and a dive atmosphere at the same time. Beds were sooo comfortable. Only downside is jacuzzi isn’t open during convenient hours."

Reviewed on Jun 27, 2026

Opens in a new windowPortland Regency Hotel & Spa
La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

3 out of 5
340 Park Ave Portland ME
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $176 total per night from Jun 29 to Jun 30
$176 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"The staff were very nice. I did find it odd that they charged a parking fee, given their location."

Reviewed on Jun 26, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Portland DT/Maine Med
Comfort Inn South Portland Airport

Comfort Inn South Portland Airport

2.5 out of 5
90 Maine Mall Rd South Portland ME
Fully refundable
$120 nightly
The price is $131 total per night from Jun 30 to Jul 1
$131 total
Jun 30 - Jul 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage of ...
"Perfect for a stay before a flight! Shuttle service and $10 a night parking while away."

Reviewed on Jun 27, 2026

Opens in a new windowComfort Inn South Portland Airport
Casco Bay Hotel Portland Airport - Maine Mall, an Ascend Collection Hotel

Casco Bay Hotel Portland Airport - Maine Mall, an Ascend Collection Hotel

3.5 out of 5
80 John Roberts Rd. South Portland ME
Fully refundable
$142 nightly
The price is $154 total per night from Jun 29 to Jun 30
$154 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free self parking, and a free airport shuttle. Business travelers can take ...
"Honestly the place wasn’t bad, I just needed a one night stay after surgery so I didn’t require many amenities. It was clean and bed was comfortable. The only bad thing is that the rooms are no where near sound proof. You can hear every single thing happening in the hallway and in the rooms next ..."

Reviewed on Jun 27, 2026

Opens in a new windowCasco Bay Hotel Portland Airport - Maine Mall, an Ascend Collection Hotel
Waves Oceanfront Resort

Waves Oceanfront Resort

3 out of 5
87 W Grand Ave Old Orchard Beach ME
$220 nightly
The price is $240 total per night from Jun 29 to Jun 30
$240 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features an outdoor pool and a gym. Enjoy the hot tub and perks like free self parking and free WiFi. A coffee shop, a lobby fireplace, and a picnic ...
"Fantastic location close to beach and a nice 5 min leisurely walk to the pier where all the food and shopping is. The swimming pool and the hot tub was also awesome. Really liked the separation of sleeping area inside the same room. The only negative was the small bathroom and outdated furniture ..."

Reviewed on Jun 27, 2026

Opens in a new windowWaves Oceanfront Resort
Clarion Pointe South Portland

Clarion Pointe South Portland

2 out of 5
675 Main Street I-95 South Portland ME
Fully refundable
$99 nightly
The price is $108 total per night from Jul 7 to Jul 8
$108 total
Jul 7 - Jul 8
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and WiFi in public areas. Enjoy ...
"Hideous hotel. They charged top dollar for a dilapidated, poorly re-decorated Version of a pig with lipstick. Hall floors uneven and a tripping hazard, our room had bubbled paint on the walls from water leaks, the floor was poorly laid plastic plans, uneven and cracked. No bar soap, thin walls and ..."

Reviewed on Jun 27, 2026

Opens in a new windowClarion Pointe South Portland
Quality Inn & Suites South Portland

Quality Inn & Suites South Portland

2.5 out of 5
738 Main Street South Portland ME
Fully refundable
$85 nightly
The price is $92 total per night from Jun 30 to Jul 1
$92 total
Jun 30 - Jul 1
Total with taxes and fees
This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free continental breakfast each morning. A garden and a picnic ...
"The hotel needs updated and cleaned thoroughly. The floors were dirt and sticky feeling and the bathrooms were super small and not clean (shower leaked on the floor). The rooms were musty smelling and damp feeling. Doors would not unlock with keycard and had to go to the office twice to get a key ..."

Reviewed on Jun 27, 2026

Opens in a new windowQuality Inn & Suites South Portland
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Casco Bay Islands hotel reviews by fellow wanderers

Comfort Inn South Portland Airport

Comfort Inn South Portland Airport

5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Perfect for a stay before a flight! Shuttle service and $10 a night parking while away."
A verified traveler stayed at Comfort Inn South Portland Airport
Comfort Inn South Portland Airport

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