Book Hotels in Casco Bay Islands, ME

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Top Casco Bay Islands hotels

Portland Harbor Hotel

Portland Harbor Hotel

4 out of 5
468 Fore Street Portland ME
Fully refundableReserve now, pay when you stay
$386 nightly
The price is $427 total per night from Jul 12 to Jul 13
$427 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features 3 coffee shops/cafes and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"Only 4 rooms that were having A/C problems. Of course we had one the rooms. If the A/C isn’t working, why continue to reserve the rooms and not just fix the A/C??? Front desk attendant Dennecia was wonderful and was able to get us moved for our last night in Portland. She made the experience enjoyable. ..."

Reviewed on Jul 8, 2026

Opens in a new windowPortland Harbor Hotel
Cambria Hotel Portland Downtown-Old Port

Cambria Hotel Portland Downtown-Old Port

3 out of 5
25 HANCOCK STREET Portland ME
Fully refundable
$284 nightly
The price is $314 total per night from Jul 12 to Jul 13
$314 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Pros: The rooms are big and spacious. Clean rooms. Well maintained Good location. Central Part of downtown. Easy access to restaurants. Gym Good size gym . All necessary equipments available. Good weights range. Cons No smart TV, was hoping to relax and watch Netflix or HBO, or HDMI port to connect ..."

Reviewed on Jul 7, 2026

Opens in a new windowCambria Hotel Portland Downtown-Old Port
Portland Regency Hotel & Spa

Portland Regency Hotel & Spa

3.5 out of 5
20 Milk Street Portland ME
Fully refundableReserve now, pay when you stay
$245 nightly
The price is $271 total per night from Jul 12 to Jul 13
$271 total
Jul 12 - Jul 13
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Unwind with a drink at one of the 2 bars/lounges and enjoy freebies ...
"Loved the place but the AC could not keep up with the heat. Room was 75 degrees."

Reviewed on Jul 8, 2026

Opens in a new windowPortland Regency Hotel & Spa
Holiday Inn Portland-By the Bay by IHG

Holiday Inn Portland-By the Bay by IHG

4 out of 5
88 Spring St Portland ME
Fully refundable
$245 nightly
The price is $271 total per night from Jul 26 to Jul 27
$271 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"We had a great visit and enjoyed the pool. The temperature was refreshing for the adults but chilly for children. The beds were comfortable and clean! The hotel was a walkable distance to shops and restaurants! We would go back again!"

Reviewed on Jul 8, 2026

Opens in a new windowHoliday Inn Portland-By the Bay by IHG
La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

3 out of 5
340 Park Ave Portland ME
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $176 total per night from Jul 13 to Jul 14
$176 total
Jul 13 - Jul 14
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Overall a fine place to stay but nothing special. Fridge was turned off when we arrived, coffee at breakfast was cold, and parking was a $10 daily charge. The humidity was also so bad the toilet bowl had constant condensation and dripped so much it created a puddle. The bed and pillows were comfortable ..."

Reviewed on Jul 8, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Portland DT/Maine Med
Comfort Inn South Portland Airport

Comfort Inn South Portland Airport

2.5 out of 5
90 Maine Mall Rd South Portland ME
Fully refundable
$139 nightly
The price is $151 total per night from Jul 12 to Jul 13
$151 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage of ...
"Clean and staff helpful."

Reviewed on Jul 9, 2026

Opens in a new windowComfort Inn South Portland Airport
Waves Oceanfront Resort

Waves Oceanfront Resort

3 out of 5
87 W Grand Ave Old Orchard Beach ME
$300 nightly
The price is $327 total per night from Jul 13 to Jul 14
$327 total
Jul 13 - Jul 14
Total with taxes and fees
This hotel features an outdoor pool and a gym. Enjoy the hot tub and perks like free self parking and free WiFi. A coffee shop, a lobby fireplace, and a picnic ...
"Our experience was simply amazing! Without a doubt, this is one of the best hotels we have ever stayed at. Everything was impeccable—the hotel is beautiful, spotless, well-organized, and extremely comfortable. The staff was incredibly kind, welcoming, and made us feel at home from the moment we arrived. ..."

Reviewed on Jul 6, 2026

Opens in a new windowWaves Oceanfront Resort
Casco Bay Hotel Portland Airport - Maine Mall, an Ascend Collection Hotel

Casco Bay Hotel Portland Airport - Maine Mall, an Ascend Collection Hotel

3.5 out of 5
80 John Roberts Rd. South Portland ME
Fully refundable
$151 nightly
The price is $165 total per night from Jul 12 to Jul 13
$165 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free self parking, and a free airport shuttle. Business travelers can take ...
"I stay here every week and every week it is spectacular and immaculate and reasonable"

Reviewed on Jul 8, 2026

Opens in a new windowCasco Bay Hotel Portland Airport - Maine Mall, an Ascend Collection Hotel
Clarion Pointe South Portland

Clarion Pointe South Portland

2 out of 5
675 Main Street I-95 South Portland ME
Fully refundable
$86 nightly
The price is $93 total per night from Jul 20 to Jul 21
$93 total
Jul 20 - Jul 21
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and WiFi in public areas. Enjoy ...
"Our biggest issue was the room smelling strongly of mildew. The property overall is somewhat dated, but decent. The pool and breakfast were nice."

Reviewed on Jul 8, 2026

Opens in a new windowClarion Pointe South Portland
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Recent Casco Bay Islands hotel reviews by fellow wanderers

Comfort Inn South Portland Airport

Comfort Inn South Portland Airport

5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Clean and staff helpful."
A verified traveler stayed at Comfort Inn South Portland Airport
Comfort Inn South Portland Airport

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