Book Hotels in Casco Bay Islands, ME

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Top Casco Bay Islands hotels

Cambria Hotel Portland Downtown-Old Port

Cambria Hotel Portland Downtown-Old Port

3 out of 5
25 HANCOCK STREET Portland ME
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $281 total per night from Jun 7 to Jun 8
$281 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"The check-in staff was very nice, and the room was great. We were a little bummed that the outside deck was not well-maintained and the fountain wasn't working."

Reviewed on Jun 5, 2026

Opens in a new windowCambria Hotel Portland Downtown-Old Port
Portland Harbor Hotel

Portland Harbor Hotel

4 out of 5
468 Fore Street Portland ME
Fully refundableReserve now, pay when you stay
$283 nightly
The price is $314 total per night from Jun 7 to Jun 8
$314 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features 3 coffee shops/cafes and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"Very nice accomodations, very pleasant and helpful staff, excellent location."

Reviewed on Jun 5, 2026

Opens in a new windowPortland Harbor Hotel
Portland Regency Hotel & Spa

Portland Regency Hotel & Spa

3.5 out of 5
20 Milk Street Portland ME
Fully refundableReserve now, pay when you stay
$207 nightly
The price is $230 total per night from Jun 7 to Jun 8
$230 total
Jun 7 - Jun 8
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Unwind with a drink at one of the 2 bars/lounges and enjoy freebies ...
"The HVAC was very loud, a faucet in the sink dripped continuously and you could hear people arguing in a neighboring room"

Reviewed on Jun 4, 2026

Opens in a new windowPortland Regency Hotel & Spa
The Westin Portland Harborview

The Westin Portland Harborview

4 out of 5
157 High St Portland ME
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $253 total per night from Jul 1 to Jul 2
$253 total
Jul 1 - Jul 2
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
"Clean and cool room."

Reviewed on Jun 5, 2026

Opens in a new windowThe Westin Portland Harborview
La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

3 out of 5
340 Park Ave Portland ME
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $146 total per night from Jun 8 to Jun 9
$146 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Th"

Reviewed on Jun 3, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Portland DT/Maine Med
Comfort Inn South Portland Airport

Comfort Inn South Portland Airport

2.5 out of 5
90 Maine Mall Rd South Portland ME
Fully refundable
$101 nightly
The price is $111 total per night from Jun 8 to Jun 9
$111 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage of ...
"Great!"

Reviewed on Jun 5, 2026

Opens in a new windowComfort Inn South Portland Airport
Clarion Hotel Portland Airport ME

Clarion Hotel Portland Airport ME

2.5 out of 5
1230 Congress St Portland ME
Fully refundable
$118 nightly
The price is $131 total per night from Jun 14 to Jun 15
$131 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Good for the price"

Reviewed on Jun 6, 2026

Opens in a new windowClarion Hotel Portland Airport ME
Spark by Hilton Portland Airport Maine Mall

Spark by Hilton Portland Airport Maine Mall

2 out of 5
461 Maine Mall Rd South Portland ME
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $100 total per night from Jun 11 to Jun 12
$100 total
Jun 11 - Jun 12
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the free WiFi in public areas and free airport shuttle. Enjoy ...
"Nice place to stay"

Reviewed on Jun 5, 2026

Opens in a new windowSpark by Hilton Portland Airport Maine Mall
Quality Inn & Suites South Portland

Quality Inn & Suites South Portland

2.5 out of 5
738 Main Street South Portland ME
Fully refundable
$99 nightly
The price is $108 total per night from Jun 7 to Jun 8
$108 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free continental breakfast each morning. A garden and a picnic ...
"Mold under the air conditioning unit, broken/loose fixtures in bathroom. Bathroom fan only sometimes worked. Noise from hallway was pretty loud (ice machine, entry doors). Mini fridge had misfitting shelf."

Reviewed on Jun 5, 2026

Opens in a new windowQuality Inn & Suites South Portland
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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