Book Hotels in Casco Bay Islands, ME

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Jul 17 - Jul 19
Next weekend
Jul 24 - Jul 26

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Casco Bay Islands hotels

Cambria Hotel Portland Downtown-Old Port

Cambria Hotel Portland Downtown-Old Port

3 out of 5
25 HANCOCK STREET Portland ME
Fully refundable
$323 nightly
The price is $357 total per night from Jul 26 to Jul 27
$357 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Clean rooms,welcoming stagf"

Reviewed on Jul 13, 2026

Opens in a new windowCambria Hotel Portland Downtown-Old Port
Portland Harbor Hotel

Portland Harbor Hotel

4 out of 5
468 Fore Street Portland ME
Fully refundableReserve now, pay when you stay
$423 nightly
The price is $468 total per night from Jul 26 to Jul 27
$468 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features 3 coffee shops/cafes and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"Our stay was great - the location of this hotel is perfect, the staff was friendly and our room was really nice. Every morning, there was a fully stocked pantry with snacks and drinks for guests on each floor. We had a great stay and would recommend this place highly!"

Reviewed on Jul 12, 2026

Opens in a new windowPortland Harbor Hotel
Portland Regency Hotel & Spa

Portland Regency Hotel & Spa

3.5 out of 5
20 Milk Street Portland ME
Fully refundableReserve now, pay when you stay
$359 nightly
The price is $397 total per night from Jul 19 to Jul 20
$397 total
Jul 19 - Jul 20
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Unwind with a drink at one of the 2 bars/lounges and enjoy freebies ...
"Its an old construction"

Reviewed on Jul 13, 2026

Opens in a new windowPortland Regency Hotel & Spa
Comfort Inn South Portland Airport

Comfort Inn South Portland Airport

2.5 out of 5
90 Maine Mall Rd South Portland ME
Fully refundable
$144 nightly
The price is $157 total per night from Jul 14 to Jul 15
$157 total
Jul 14 - Jul 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage of ...
"Was great for us as last minute planning and able to check in late. Room was nice and had everything needed. Friendly staff. I was late for breakfast but still got my coffee and a fruit. Parking was fine. Would stay here again."

Reviewed on Jul 13, 2026

Opens in a new windowComfort Inn South Portland Airport
La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

3 out of 5
340 Park Ave Portland ME
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $198 total per night from Jul 26 to Jul 27
$198 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Very courteous staff. Conveniently located to the airport."

Reviewed on Jul 13, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Portland DT/Maine Med
Clarion Hotel Portland Airport ME

Clarion Hotel Portland Airport ME

2.5 out of 5
1230 Congress St Portland ME
Fully refundable
$144 nightly
The price is $159 total per night from Jul 26 to Jul 27
$159 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Love the hot tub although it obviously was not cleaned after closing between 10p-6a There were no towels available at 6:30 am The floor surface of the pool area needs attention. The pebble surface is loose and pulling up in some ares and pebbles are getting tracked int to pool. We enjoyed using the ..."

Reviewed on Jul 13, 2026

Opens in a new windowClarion Hotel Portland Airport ME
Fireside Inn & Suites Portland

Fireside Inn & Suites Portland

3 out of 5
81 Riverside St Portland ME
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $159 total per night from Jul 14 to Jul 15
$159 total
Jul 14 - Jul 15
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the seasonal ...
"good for a quick clean affordable stay, 24hr front desk was awesome for me traveling. Will say there is NO airport shuttle as Expedia claims, but it’s a quick 4mi drive"

Reviewed on Jul 13, 2026

Opens in a new windowFireside Inn & Suites Portland
Old Orchard Beach Inn

Old Orchard Beach Inn

2.5 out of 5
6 Portland Ave Old Orchard Beach ME
Fully refundableReserve now, pay when you stay
$160 nightly
The price is $175 total per night from Jul 14 to Jul 15
$175 total
Jul 14 - Jul 15
Total with taxes and fees
A seasonal outdoor pool, free self parking, and wedding services are featured at this bed & breakfast. WiFi in public areas is free. A garden, a library, and ...
"The Inn is a beautiful and historical building, kept immaculately clean. Each room is unique, but each also includes a refrigerator and updated bathroom. It is located at the top of the main street in Old Orchard Beach, making it the perfect location to visit. The staff is always welcoming and helpful. ..."

Reviewed on Jul 13, 2026

Opens in a new windowOld Orchard Beach Inn
Clarion Pointe South Portland

Clarion Pointe South Portland

2 out of 5
675 Main Street I-95 South Portland ME
Fully refundable
$90 nightly
The price is $98 total per night from Jul 21 to Jul 22
$98 total
Jul 21 - Jul 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and WiFi in public areas. Enjoy ...
"Staff was very good. I called Ahmed for an early arrival and he was great. Rooms are somewhat dated and need some TLC but beds were excellent."

Reviewed on Jul 13, 2026

Opens in a new windowClarion Pointe South Portland
Don't see what you're looking for?
See all available properties in Casco Bay Islands
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Casco Bay Islands hotel reviews by fellow wanderers

Cambria Hotel Portland Downtown-Old Port

Cambria Hotel Portland Downtown-Old Port

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Clean rooms,welcoming stagf"
A verified traveler stayed at Cambria Hotel Portland Downtown-Old Port
Cambria Hotel Portland Downtown-Old Port

Explore More Ways to Travel with Travelocity