Book Hotels in Casco Bay Islands, ME
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Top Casco Bay Islands hotels

Portland Harbor Hotel
468 Fore Street Portland ME
Fully refundableReserve now, pay when you stay
$349 nightly
The price is $386 total per night from Jun 14 to Jun 15
$386 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features 3 coffee shops/cafes and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"Very nice accomodations, very pleasant and helpful staff, excellent location."
Reviewed on Jun 5, 2026

Cambria Hotel Portland Downtown-Old Port
25 HANCOCK STREET Portland ME
Fully refundableReserve now, pay when you stay
$277 nightly
The price is $306 total per night from Jun 28 to Jun 29
$306 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Great service"
Reviewed on Jun 7, 2026

Portland Regency Hotel & Spa
20 Milk Street Portland ME
Fully refundableReserve now, pay when you stay
$280 nightly
The price is $309 total per night from Jun 15 to Jun 16
$309 total
Jun 15 - Jun 16
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Unwind with a drink at one of the 2 bars/lounges and enjoy freebies ...
"Lovely outdoor café associated with the hotel across the street. Great food. The garlic lemon hummus with pistachio gremolata was the best hummus I've ever had. Wraps were excellent. Room was quiet and bed was very comfortable. Breakfast at the hotel was great and service was excellent. Hotel is ..."
Reviewed on Jun 6, 2026

The Westin Portland Harborview
157 High St Portland ME
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $253 total per night from Jul 1 to Jul 2
$253 total
Jul 1 - Jul 2
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
"Clean and cool room."
Reviewed on Jun 5, 2026

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med
340 Park Ave Portland ME
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $143 total per night from Jun 8 to Jun 9
$143 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Poor breakfast Bathroom door warped"
Reviewed on Jun 6, 2026

Casco Bay Hotel Portland Airport - Maine Mall, an Ascend Collection Hotel
80 John Roberts Rd. South Portland ME
Fully refundable
$94 nightly
The price is $103 total per night from Jun 8 to Jun 9
$103 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free self parking, and a free airport shuttle. Business travelers can take ...
"The room was very clean and the staff was very helpful."
Reviewed on Jun 6, 2026

Clarion Hotel Portland Airport ME
1230 Congress St Portland ME
Fully refundable
$118 nightly
The price is $131 total per night from Jun 14 to Jun 15
$131 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"A bit outdated. Rug on the floors was shabby. Transportation person was grumpy. Not enough shampoo and conditioner in room. But the cost was economical."
Reviewed on Jun 7, 2026

Clarion Pointe South Portland
675 Main Street I-95 South Portland ME
Fully refundable
$70 nightly
The price is $76 total per night from Jun 8 to Jun 9
$76 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and WiFi in public areas. Enjoy ...
"Rooms and hall were really dirty. Covers had dirt and hair on them. No way they were changed. You trust bedding will at least be cleaned. Heavy smell of weed everywhere."
Reviewed on Jun 6, 2026

Quality Inn & Suites South Portland
738 Main Street South Portland ME
Fully refundable
$101 nightly
The price is $110 total per night from Jun 8 to Jun 9
$110 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free continental breakfast each morning. A garden and a picnic ...
"It was a really comfy stay, what I needed for the old port half marathon"
Reviewed on Jun 7, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Casco Bay Islands with star-rating
Check Casco Bay Islands Hotels by Star Rating

4 Star Hotels
15 properties
Recent Casco Bay Islands hotel reviews by fellow wanderers

Quality Inn & Suites South Portland
5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"It was a really comfy stay, what I needed for the old port half marathon"
A verified traveler stayed at Quality Inn & Suites South Portland
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