Book Hotels in Casco Bay Islands, ME
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Top Casco Bay Islands hotels
Portland Harbor Hotel
468 Fore Street Portland ME
Fully refundableReserve now, pay when you stay
$308 nightly
The price is $340 total per night from Jul 5 to Jul 6
$340 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features 3 coffee shops/cafes and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"We didn't sleep! The AC unit banged and shuttered and roared every time it shut on throughout the night and literally made the room unsleepable. I mentioned it to the receptionist at the front desk the next morning and there was no follow up or response. It was an expensive room that we booked on ..."
Reviewed on Jun 18, 2026
Cambria Hotel Portland Downtown-Old Port
25 HANCOCK STREET Portland ME
Fully refundable
$266 nightly
The price is $294 total per night from Jun 21 to Jun 22
$294 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Love valet parking. Location is great. BED & pillows so comfortable."
Reviewed on Jun 18, 2026
La Quinta Inn & Suites by Wyndham Portland DT/Maine Med
340 Park Ave Portland ME
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $154 total per night from Jun 22 to Jun 23
$154 total
Jun 22 - Jun 23
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Good one night stop for us."
Reviewed on Jun 18, 2026
Comfort Inn South Portland Airport
90 Maine Mall Rd South Portland ME
Fully refundable
$112 nightly
The price is $123 total per night from Jun 28 to Jun 29
$123 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage of ...
"Fine"
Reviewed on Jun 18, 2026
Casco Bay Hotel Portland Airport - Maine Mall, an Ascend Collection Hotel
80 John Roberts Rd. South Portland ME
Fully refundable
$123 nightly
The price is $134 total per night from Jun 21 to Jun 22
$134 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free self parking, and a free airport shuttle. Business travelers can take ...
"As a business traveler, I have switched to this hotel because the clients are all a better caliber of some of the other hotels that I’ve been staying in in the area. There is breakfast and coffee that is totally fine and the property is super convenient to local shopping and the highways the room ..."
Reviewed on Jun 17, 2026
Clarion Hotel Portland Airport ME
1230 Congress St Portland ME
Fully refundable
$110 nightly
The price is $121 total per night from Jun 29 to Jun 30
$121 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"A 1 night stay to catch a flight, super clean, quiet and comfy beds!"
Reviewed on Jun 18, 2026
Clarion Pointe South Portland
675 Main Street I-95 South Portland ME
Fully refundable
$93 nightly
The price is $101 total per night from Jun 21 to Jun 22
$101 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and WiFi in public areas. Enjoy ...
"Horrible."
Reviewed on Jun 18, 2026
Quality Inn & Suites South Portland
738 Main Street South Portland ME
Fully refundable
$78 nightly
The price is $85 total per night from Jun 25 to Jun 26
$85 total
Jun 25 - Jun 26
Total with taxes and fees
This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free continental breakfast each morning. A garden and a picnic ...
"Breakfast on the first morning was not great but this got greatly improved for the rest of my stay. The staff was friendly and helpful."
Reviewed on Jun 19, 2026
Portland Regency Hotel & Spa
20 Milk Street Portland ME
Fully refundableReserve now, pay when you stay
$322 nightly
The price is $357 total per night from Jun 28 to Jun 29
$357 total
Jun 28 - Jun 29
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Unwind with a drink at one of the 2 bars/lounges and enjoy freebies ...
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See all available properties in Casco Bay Islands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Casco Bay Islands with star-rating
Check Casco Bay Islands Hotels by Star Rating
4 Star Hotels
15 properties
Recent Casco Bay Islands hotel reviews by fellow wanderers
Quality Inn & Suites South Portland
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Breakfast on the first morning was not great but this got greatly improved for the rest of my stay. The staff was friendly and helpful."
A verified traveler stayed at Quality Inn & Suites South Portland
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