Book Hotels in Casco Bay Islands, ME
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Top Casco Bay Islands hotels
Portland Harbor Hotel
468 Fore Street Portland ME
Fully refundableReserve now, pay when you stay
$322 nightly
The price is $356 total per night from Jun 28 to Jun 29
$356 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features 3 coffee shops/cafes and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"Did not like that our room was next to the bar across the street. Heard the music until 1 AM Only stayed one night or we would have requested another room."
Reviewed on Jun 24, 2026
Cambria Hotel Portland Downtown-Old Port
25 HANCOCK STREET Portland ME
Fully refundableReserve now, pay when you stay
$284 nightly
The price is $315 total per night from Jun 28 to Jun 29
$315 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Staff was great. Check in was on the 4th floor. Good location"
Reviewed on Jun 24, 2026
Portland Regency Hotel & Spa
20 Milk Street Portland ME
$242 nightly
The price is $268 total per night from Jul 1 to Jul 2
$268 total
Jul 1 - Jul 2
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Unwind with a drink at one of the 2 bars/lounges and enjoy freebies ...
"Excellent location, we did not need a car during our visit!"
Reviewed on Jun 24, 2026
La Quinta Inn & Suites by Wyndham Portland DT/Maine Med
340 Park Ave Portland ME
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $154 total per night from Jun 29 to Jun 30
$154 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Stay away from this place. They charge you to park in their lot. And the worst part is that the room was dirty & the sheets looked they haven’t been changed. They had hair on the sheets & the pillows were also smelly & im not sure what they were stuffed with. It’s not close by to any places to eat. ..."
Reviewed on Jun 24, 2026
Comfort Inn South Portland Airport
90 Maine Mall Rd South Portland ME
Fully refundable
$116 nightly
The price is $127 total per night from Jun 28 to Jun 29
$127 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage of ...
"Great stay."
Reviewed on Jun 24, 2026
Casco Bay Hotel Portland Airport - Maine Mall, an Ascend Collection Hotel
80 John Roberts Rd. South Portland ME
Fully refundable
$123 nightly
The price is $134 total per night from Jun 28 to Jun 29
$134 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free self parking, and a free airport shuttle. Business travelers can take ...
"I appreciated the very helpful assistance with airport transportation."
Reviewed on Jun 24, 2026
Clarion Hotel Portland Airport ME
1230 Congress St Portland ME
Fully refundable
$123 nightly
The price is $136 total per night from Jun 29 to Jun 30
$136 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Clean, comfortable and all you need"
Reviewed on Jun 24, 2026
Ramada Plaza by Wyndham Portland
155 Riverside St Portland ME
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $142 total per night from Jun 28 to Jun 29
$142 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features 2 restaurants, 2 hot tubs, and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Nice clean stay, shower had good pressures"
Reviewed on Jun 20, 2026
Clarion Pointe South Portland
675 Main Street I-95 South Portland ME
Fully refundable
$99 nightly
The price is $108 total per night from Jul 1 to Jul 2
$108 total
Jul 1 - Jul 2
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and WiFi in public areas. Enjoy ...
"Very nice people"
Reviewed on Jun 23, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Casco Bay Islands with star-rating
Check Casco Bay Islands Hotels by Star Rating
4 Star Hotels
15 properties
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