Book Hotels in Casco Bay Islands, ME
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Top Casco Bay Islands hotels

Portland Harbor Hotel
468 Fore Street Portland ME
Fully refundableReserve now, pay when you stay
$308 nightly
The price is $340 total per night from Jul 5 to Jul 6
$340 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features 3 coffee shops/cafes and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"Beautiful hotel, great location, friendly associates, but would not return to this location. Unfortunately many negatives.They offer what they call is a “kitchen” on every floor- coffee maker did not work and the ice machine did not work- spoke to an associate and was told coffee machine has been ..."
Reviewed on Jun 20, 2026

Cambria Hotel Portland Downtown-Old Port
25 HANCOCK STREET Portland ME
Fully refundable
$287 nightly
The price is $318 total per night from Jun 30 to Jul 1
$318 total
Jun 30 - Jul 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"I loved staying at Cambria in Portland. The location was perfect; the rooms were spacious and clean. The pillows were really comfortable. The staff was excellent."
Reviewed on Jun 20, 2026

Portland Regency Hotel & Spa
20 Milk Street Portland ME
Fully refundableReserve now, pay when you stay
$230 nightly
The price is $255 total per night from Jun 29 to Jun 30
$255 total
Jun 29 - Jun 30
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Unwind with a drink at one of the 2 bars/lounges and enjoy freebies ...
"Really enjoyed our stay here. The room was large, clean, and cute. Staff was super nice, especially valet. Location was great and super walkable to everything within Portland. Highly recommend."
Reviewed on Jun 21, 2026

Holiday Inn Portland-By the Bay by IHG
88 Spring St Portland ME
Fully refundable
$182 nightly
The price is $201 total per night from Jun 28 to Jun 29
$201 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"The 3:00 check in time was delayed until 4:40 due to, “rooms not cleaned due to being short staffed.” This is not a huge surprise but the staff was repeatedly rude while communicating this. Most of the front desk and restaurant staff were rude for the first three days of our stay. The hotel looked ..."
Reviewed on Jun 20, 2026

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med
340 Park Ave Portland ME
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $138 total per night from Jun 22 to Jun 23
$138 total
Jun 22 - Jun 23
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"The property was very clean and quiet. The outside parking was ample and the surface had just been re-paved. The room was clean and comfortable, the a/c worked great and we had plenty of hot water with adequate water pressure. Breakfast was simple (bagels, waffle, cereal, eggs/sausage)but adequate. ..."
Reviewed on Jun 19, 2026

Comfort Inn South Portland Airport
90 Maine Mall Rd South Portland ME
Fully refundable
$112 nightly
The price is $123 total per night from Jun 28 to Jun 29
$123 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage of ...
"Young lady shuttle driver was excellent"
Reviewed on Jun 21, 2026

Clarion Hotel Portland Airport ME
1230 Congress St Portland ME
Fully refundable
$110 nightly
The price is $121 total per night from Jun 29 to Jun 30
$121 total
Jun 29 - Jun 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Very friendly and helpful staff. Good location if traveling by bus - right next to the bus station."
Reviewed on Jun 21, 2026

Ramada Plaza by Wyndham Portland
155 Riverside St Portland ME
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $148 total per night from Jun 28 to Jun 29
$148 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features 2 restaurants, 2 hot tubs, and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Nice clean stay, shower had good pressures"
Reviewed on Jun 20, 2026

Clarion Pointe South Portland
675 Main Street I-95 South Portland ME
Fully refundable
$99 nightly
The price is $108 total per night from Jun 28 to Jun 29
$108 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and WiFi in public areas. Enjoy ...
"Basic but did as described. Room okay but had a dripping shower. Breakfast, again basic but sufficient."
Reviewed on Jun 20, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Casco Bay Islands with star-rating
Check Casco Bay Islands Hotels by Star Rating

4 Star Hotels
15 properties
Recent Casco Bay Islands hotel reviews by fellow wanderers

Clarion Hotel Portland Airport ME
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Very friendly and helpful staff. Good location if traveling by bus - right next to the bus station."
A verified traveler stayed at Clarion Hotel Portland Airport ME
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