Book Hotels in Casco Bay Islands, ME

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Casco Bay Islands hotels

Cambria Hotel Portland Downtown-Old Port

Cambria Hotel Portland Downtown-Old Port

3 out of 5
25 HANCOCK STREET Portland ME
Fully refundable
$256 nightly
The price is $283 total per night from Jun 7 to Jun 8
$283 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"super spacious room, friendly staff, towels are so soft, great experience"

Reviewed on Jun 3, 2026

Opens in a new windowCambria Hotel Portland Downtown-Old Port
Portland Harbor Hotel

Portland Harbor Hotel

4 out of 5
468 Fore Street Portland ME
Fully refundableReserve now, pay when you stay
$304 nightly
The price is $336 total per night from Jun 7 to Jun 8
$336 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features 3 coffee shops/cafes and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
"The property and room was clean and well maintained. The hotel overall and its amenities are spectacular. It was the service by a lot of the staff that drives my rating. The male at the front desk at night gave me the wrong room and asked if my friend could just use the pull out bed, since they were ..."

Reviewed on Jun 5, 2026

Opens in a new windowPortland Harbor Hotel
Portland Regency Hotel & Spa

Portland Regency Hotel & Spa

3.5 out of 5
20 Milk Street Portland ME
Fully refundableReserve now, pay when you stay
$260 nightly
The price is $288 total per night from Jun 7 to Jun 8
$288 total
Jun 7 - Jun 8
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Unwind with a drink at one of the 2 bars/lounges and enjoy freebies ...
"The HVAC was very loud, a faucet in the sink dripped continuously and you could hear people arguing in a neighboring room"

Reviewed on Jun 4, 2026

Opens in a new windowPortland Regency Hotel & Spa
The Westin Portland Harborview

The Westin Portland Harborview

4 out of 5
157 High St Portland ME
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $253 total per night from Jul 1 to Jul 2
$253 total
Jul 1 - Jul 2
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
"Great stay except it took the hot water 10 minutes to come through for shower and sink."

Reviewed on Jun 2, 2026

Opens in a new windowThe Westin Portland Harborview
La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

La Quinta Inn & Suites by Wyndham Portland DT/Maine Med

3 out of 5
340 Park Ave Portland ME
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $146 total per night from Jun 7 to Jun 8
$146 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Th"

Reviewed on Jun 3, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Portland DT/Maine Med
Comfort Inn South Portland Airport

Comfort Inn South Portland Airport

2.5 out of 5
90 Maine Mall Rd South Portland ME
Fully refundable
$92 nightly
The price is $100 total per night from Jun 7 to Jun 8
$100 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage of ...
"Good breakfast! Very safe area and close to shopping"

Reviewed on Jun 5, 2026

Opens in a new windowComfort Inn South Portland Airport
Clarion Hotel Portland Airport ME

Clarion Hotel Portland Airport ME

2.5 out of 5
1230 Congress St Portland ME
Fully refundable
$118 nightly
The price is $131 total per night from Jun 11 to Jun 12
$131 total
Jun 11 - Jun 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Staff was very friendly and helpful. The hotel is "nice" not fancy but clean and comfortable. Breakfast included was listed but not so! although they did have a good breakfast menu available for a very reasonable cost, right on site."

Reviewed on Jun 4, 2026

Opens in a new windowClarion Hotel Portland Airport ME
Spark by Hilton Portland Airport Maine Mall

Spark by Hilton Portland Airport Maine Mall

2 out of 5
461 Maine Mall Rd South Portland ME
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $99 total per night from Jun 7 to Jun 8
$99 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the free WiFi in public areas and free airport shuttle. Enjoy ...
"Everything was clean except for the comforter on the bed it smelled weird and had a few stains on it theyre continental breakfast consisted of ceral and bagels the you toast yourself so I wouldnt exactly call it breakfast thr staff was super nice though"

Reviewed on Jun 4, 2026

Opens in a new windowSpark by Hilton Portland Airport Maine Mall
Quality Inn & Suites South Portland

Quality Inn & Suites South Portland

2.5 out of 5
738 Main Street South Portland ME
Fully refundable
$94 nightly
The price is $103 total per night from Jun 7 to Jun 8
$103 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features free WiFi in public areas, free newspapers, and free self parking. Enjoy the free continental breakfast each morning. A garden and a picnic ...
"Do not stay here. I had to change rooms because the bathroom and beds and floors were filthy (pubic hairs, stains, food). The faucet on the sink was broken. We moved to a different room. The hvac unit did not work by beds in the second room. We stayed multiple nights and only received housekeeping ..."

Reviewed on Jun 3, 2026

Opens in a new windowQuality Inn & Suites South Portland
Don't see what you're looking for?
See all available properties in Casco Bay Islands
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Casco Bay Islands hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity