Explore top 2026 4 Star Hotels in O'Fallon

Name: St. Louis Union Station Hotel, Curio Collection by Hilton
Price range: $169 total
Rating: 8.4

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Top O'Fallon 4 Star hotels

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO

Fully refundableReserve now, pay when you stay

$101 nightly

$120 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.6/10 Excellent! (1,144 reviews)

Loved staying here, it was very clean and beautifully decorated.. friendly service and very close to my venue

Reviewed on Dec 8, 2025

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO

Fully refundableReserve now, pay when you stay

$95 nightly

$111 total

Dec 21 - Dec 22

Total with taxes and fees

This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...

8.4/10 Very Good! (4,011 reviews)

Nice rooms. Great location. Check-in process needs improvement.

Reviewed on Dec 8, 2025

21C Museum Hotel St Louis

1528 Locust street St. Louis MO

Fully refundableReserve now, pay when you stay

$131 nightly

$153 total

Dec 28 - Dec 29

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (1,477 reviews)

Staff is wonderful. We checked in late after a long journey and they could not have been nicer to us at check in also in the restaurant and bar. We loved the vibe and the location. I’d return again if ever in the area.

Reviewed on Dec 2, 2025

The Cheshire

6300 Clayton Rd Richmond Heights MO

Fully refundableReserve now, pay when you stay

$129 nightly

$153 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

8.6/10 Excellent! (1,000 reviews)

It was wonderful!

Reviewed on Dec 3, 2025

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

3550 Samuel Sheppard Drive St. Louis MO

$119 nightly

$141 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...

8.8/10 Excellent! (1,029 reviews)

Great

Reviewed on Dec 2, 2025

Live by Loews - St.Louis

799 Clark ave St. Louis MO

Fully refundableReserve now, pay when you stay

$149 nightly

$177 total

Dec 14 - Dec 15

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

9.2/10 Wonderful! (1,097 reviews)

Next to the Baseball stadium

Reviewed on Dec 1, 2025

The Westin St. Louis

811 Spruce St St. Louis MO

Fully refundableReserve now, pay when you stay

$127 nightly

$148 total

Dec 14 - Dec 15

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.4/10 Very Good! (1,003 reviews)

It was good

Reviewed on Dec 8, 2025

DoubleTree by Hilton St. Louis Forest Park

4550 Forest Park Ave St. Louis MO

Fully refundableReserve now, pay when you stay

$114 nightly

$134 total

Dec 22 - Dec 23

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, ...

8.2/10 Very Good! (1,001 reviews)

The room was clean but the glass glasses did not look clean to me. Also, I found this strange and I know there was nothing meant to be unkind by it. When we checked in I sat on a sofa near the desk where there were two employees . It was not busy at all. My husband went to park our vehicle. It was ...

Reviewed on Dec 1, 2025

River City Casino & Hotel

777 River City Casino Blvd St. Louis MO

Fully refundableReserve now, pay when you stay

$96 nightly

$112 total

Dec 17 - Dec 18

Total with taxes and fees

This hotel features a casino, a nightclub, and 5 restaurants. Traveling on business? Take advantage of the business center, conference center, and conference ...

9/10 Wonderful! (1,449 reviews)

Clean room and place smells great. Burger restaurant open to 2:00 for late night burger.

Reviewed on Dec 8, 2025

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street St. Louis MO

$142 nightly

$169 total

Dec 18 - Dec 19

Total with taxes and fees

This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...

8.4/10 Very Good! (1,006 reviews)

The staff was helpful every step along the way.

Reviewed on Dec 8, 2025

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4 Star Hotels O'Fallon

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in O'Fallon 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in O'Fallon will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in O'Fallon, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.