Explore top 2026 4 Star Hotels in Roxana

Name: St. Louis Union Station Hotel, Curio Collection by Hilton
Price range: $186 total
Rating: 8.4

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Top Roxana 4 Star hotels

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO

Fully refundableReserve now, pay when you stay

$87 nightly

$104 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.6/10 Excellent! (1,207 reviews)

Super helpful staff! The hotel lobby has so much character!

Reviewed on Jan 20, 2026

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO

Fully refundableReserve now, pay when you stay

$149 nightly

$176 total

Jan 24 - Jan 25

Total with taxes and fees

This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...

8.4/10 Very Good! (4,046 reviews)

There was still an old coffee pod in the coffee maker. Hotels are creepy and weird. This one wasn’t any different. The view was nice. The beds and bathroom were clean.

Reviewed on Jan 19, 2026

21C Museum Hotel St Louis

1528 Locust street St. Louis MO

Fully refundableReserve now, pay when you stay

$148 nightly

$173 total

Feb 22 - Feb 23

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (1,560 reviews)

Great hotel! Art, food and drinks were fantastic

Reviewed on Jan 18, 2026

The Cheshire

6300 Clayton Rd Richmond Heights MO

Fully refundableReserve now, pay when you stay

$126 nightly

$150 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

8.6/10 Excellent! (1,010 reviews)

Loved the themes and the decor. Enjoyed the places to eat and drink without having to drive anywhere. Close to the park with the zoo and art museum.

Reviewed on Jan 19, 2026

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road St. Louis MO

Fully refundableReserve now, pay when you stay

$118 nightly

$138 total

Jan 31 - Feb 1

Total with taxes and fees

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

8.4/10 Very Good! (1,066 reviews)

Our check in was flawless as always and the staff was very friendly

Reviewed on Jan 11, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

3550 Samuel Sheppard Drive St. Louis MO

Fully refundableReserve now, pay when you stay

$127 nightly

$150 total

Jan 26 - Jan 27

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...

8.8/10 Excellent! (1,053 reviews)

Easy check-

Reviewed on Jan 19, 2026

Live by Loews - St.Louis

799 Clark ave St. Louis MO

Fully refundableReserve now, pay when you stay

$149 nightly

$177 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

9.2/10 Wonderful! (1,108 reviews)

Amazing rooms that are clean with fantastic views. Valet staff was wonderful and attentive. Check in was a breeze with all the info we needed for our stay. Bartender at restaurant was wonderful and kind.

Reviewed on Jan 4, 2026

The Westin St. Louis

811 Spruce St St. Louis MO

Fully refundableReserve now, pay when you stay

$127 nightly

$148 total

Feb 1 - Feb 2

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...

8.6/10 Excellent! (1,002 reviews)

Nice facility, spacious rooms, clean hotel, located next to Ballpark Village with lots of bars and restaurants

Reviewed on Jan 19, 2026

DoubleTree by Hilton St. Louis Forest Park

4550 Forest Park Ave St. Louis MO

Fully refundableReserve now, pay when you stay

$119 nightly

$140 total

Feb 1 - Feb 2

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, ...

8.2/10 Very Good! (1,005 reviews)

Room was clean. Check in was a breeze.

Reviewed on Jan 15, 2026

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street St. Louis MO

Fully refundableReserve now, pay when you stay

$157 nightly

$186 total

Jan 29 - Jan 30

Total with taxes and fees

This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...

8.4/10 Very Good! (1,002 reviews)

Superb customer service!! Location! Amenities! Light show! Breakfast! Downfall, but definitely not a deal breaker...LONG walk to our room! We got our steps in for sure!

Reviewed on Jan 19, 2026

Don't see what you're looking for?

See all available properties in Roxana

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Roxana

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Roxana 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Roxana will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Roxana, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.