Book Hotels in Roxana, IL

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Top Roxana hotels

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from May 3 to May 4
$106 total
May 3 - May 4
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Check in was easy and the room was clean and inviting after 12 hours of flying.

Reviewed on Apr 21, 2026

Opens in a new windowPear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
$162 nightly
The price is $189 total per night from May 3 to May 4
$189 total
May 3 - May 4
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
Overall, a great value for the price. I would absolutely stay there again. Perfectly located. Easy to find. Incredible staff. The breakfast ladies are the best. I'm not a morning person & I left smiling every morning. Good food. Evening appetizers were easily a meal. We enjoyed visiting with other ...

Reviewed on Apr 21, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
$159 nightly
The price is $189 total per night from May 10 to May 11
$189 total
May 10 - May 11
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Perfectly located

Reviewed on Apr 20, 2026

Opens in a new windowLive by Loews - St.Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $116 total per night from May 3 to May 4
$116 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Breakfast was great especially with a toddler. The parking was also very convenient and fair! Room is slightly dated but the bathrooms have been renovated. Good place to rest your head and explore the rest of the city.

Reviewed on Apr 21, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $183 total per night from May 3 to May 4
$183 total
May 3 - May 4
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
No free parking at hotel, only choice of valet for $50 or monitoring your own street parking using a parking app. One elevator was broken during our stay; this place was NOT a 4 star hotel experience. The only 2 redeeming qualities was the staff was friendly and the museum had cool art.

Reviewed on Apr 22, 2026

Opens in a new window21C Museum Hotel St Louis
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave St. Louis MO
$122 nightly
The price is $143 total per night from May 3 to May 4
$143 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Loved it

Reviewed on Apr 21, 2026

Opens in a new windowHampton Inn St. Louis-Downtown (At the Gateway Arch)
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $141 total per night from May 1 to May 2
$141 total
May 1 - May 2
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
The hot tub was wonderful and the front desk staff and the lady working the happy gour thing were all amazing. Super friendly and gave above and beyond service making me feel welcome.

Reviewed on Apr 21, 2026

Opens in a new windowPear Tree Inn St. Louis Near Union Station
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $161 total per night from May 8 to May 9
$161 total
May 8 - May 9
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
Great location

Reviewed on Apr 20, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from May 8 to May 9
$143 total
May 8 - May 9
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
Opens in a new windowRenaissance St. Louis Airport Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Roxana?
From well-designed amenities to extra room to move, kid-friendly hotels are equipped with features that can help transform a regular family vacation into an incredible one. These Roxana options make vacationing with your youngsters a snap: The whole team will love staying at Bel Air Motel. Front desk services and a picnic area are among the things that help make this place a winner. Best Western Premier Alton-St. Louis Area Hotel is also a great choice. After an exciting day of exploring Roxana, come back home to your comfy room and amenities like a swimming pool and pet-friendly facilities.
Where can I find cheap hotels in Roxana?
At Travelocity you'll find really nice hotels in Roxana at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Roxana rather than in Roxana. We may find you even better rates, too.
How do I find the best Roxana hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Roxana then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Roxana?
The cheapest hotel in Roxana is $106. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Roxana?
There are 1,429 hotels in Roxana on Travelocity.
What are the best hotels in Roxana?
Roxana has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Roxana for you!
When is the best time to visit Roxana?
If you want the joy of a fun-filled trip in peak season, visit Roxana during June, July and August. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Roxana?
Based on historic data is usually the cheapest month to visit Roxana. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Roxana?
There are multiple hotels in Roxana that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Roxana. We have plenty of kid-friendly hotels in Roxana to choose from on Travelocity!
Why book a hotel in Roxana through Travelocity?
Because we have the top hotels in Roxana! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Roxana on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Roxana hotel reviews by fellow wanderers

21C Museum Hotel St Louis

21C Museum Hotel St Louis

3 out of 5
Posted 7 hours ago
Travelocity Verified Review
"No free parking at hotel, only choice of valet for $50 or monitoring your own street parking using a parking app. One elevator was broken during our stay; this place was NOT a 4 star hotel experience. The only 2 redeeming qualities was the staff was friendly and the museum had cool art."
A verified traveler stayed at 21C Museum Hotel St Louis
21C Museum Hotel St Louis

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