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Top Roxana hotels

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $150 total per night from Dec 13 to Dec 14
$150 total
Dec 13 - Dec 14
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Ok. This is like the very first Drury hotel and it is pristine. The value is all there and it is fully 4-5 stars. The only problem is you have to pay $28+ for parking.
Reviewed on Dec 2, 2025

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Dec 28 to Dec 29
$153 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Staff is wonderful. We checked in late after a long journey and they could not have been nicer to us at check in also in the restaurant and bar. We loved the vibe and the location. I’d return again if ever in the area.
Reviewed on Dec 2, 2025

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $115 total per night from Dec 19 to Dec 20
$115 total
Dec 19 - Dec 20
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Love the breakfast buffet! Something for everyone. Staff is always friendly and helpful. I plan to stay at this hotel anytime I’m near it. I always feel so welcome.
Reviewed on Nov 30, 2025

Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Dec 11 to Dec 12
$110 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Our stay was great, minus the fact that the hot tub was out of service. It was one of the reasons we chose this hotel so we (the parents) were disappointed. But the kids loved the pool! There were plenty of breakfast options, though adding one more waffle maker would alleviate the long wait to make ...
Reviewed on Dec 1, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $120 total per night from Dec 11 to Dec 12
$120 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
Great
Reviewed on Dec 2, 2025

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
333 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $111 total per night from Dec 13 to Dec 14
$111 total
Dec 13 - Dec 14
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Nice clean room. Very friendly staff. Good view of the Arch
Reviewed on Dec 2, 2025

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $111 total per night from Dec 21 to Dec 22
$111 total
Dec 21 - Dec 22
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
The room was very spacious and clean! The staff was friendly and accommodating!
Reviewed on Dec 1, 2025

St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $171 total per night from Dec 14 to Dec 15
$171 total
Dec 14 - Dec 15
Total with taxes and fees
This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...
Great Staff!
Reviewed on Dec 1, 2025

Hilton St. Louis Airport
10330 Natural Bridge Rd St. Louis MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $112 total per night from Dec 14 to Dec 15
$112 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the express check-in, express check-out, and free ...
Tesla charger does not agrr
Reviewed on Dec 3, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Roxana with star-rating
Check Roxana Hotels by Star Rating

4 Star Hotels
58 properties
Frequently asked questions
Recent Roxana hotel reviews by fellow wanderers

21C Museum Hotel St Louis
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Staff is wonderful. We checked in late after a long journey and they could not have been nicer to us at check in also in the restaurant and bar. We loved the vibe and the location. I’d return again if ever in the area. "
A verified traveler stayed at 21C Museum Hotel St Louis
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