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Top Roxana hotels

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Mar 15 to Mar 16
$158 total
Mar 15 - Mar 16
Total with taxes and fees
2 hot tubs, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in ...
Staff was very friendly, very clean hotel.
Reviewed on Mar 6, 2026

Drury Inn & Suites St. Louis Union Station
201 S 20th St St. Louis MO
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $162 total per night from Mar 15 to Mar 16
$162 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Rooms are very small and poorly decorated but clean. (Currently property is under renovation, so decor should be updated soon). Pool and hot tub areas clean but definitely showing their age! (Just look old and water feature on the wall has hard water buildup making it look dirty and again old). The ...
Reviewed on Mar 7, 2026

Live by Loews - St.Louis
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $177 total per night from Apr 3 to Apr 4
$177 total
Apr 3 - Apr 4
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Room was excellent clean no issues
Reviewed on Mar 7, 2026

Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Mar 15 to Mar 16
$106 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
It was fine
Reviewed on Mar 7, 2026

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $153 total per night from Apr 5 to Apr 6
$153 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Unique hotel, would stay again
Reviewed on Mar 7, 2026

Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $124 total per night from Mar 15 to Mar 16
$124 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
This was a great value hotel. The rooms were clean the air conditioning worked well, and the room included a free three drink happy hour
Reviewed on Mar 7, 2026

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $122 total per night from Mar 29 to Mar 30
$122 total
Mar 29 - Mar 30
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
I stayed here in 2025 and made sure to return when in town again. The rooms are great, the price is reasonable, and the free breakfast was outstanding. Also, the parking garage is priced reasonably and I saved a lot of money leaving my car at the hotel and taking the light rail downtown.
Reviewed on Mar 4, 2026

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $199 total per night from Mar 23 to Mar 24
$199 total
Mar 23 - Mar 24
Total with taxes and fees
This smoke-free hotel's 3 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...
It was sn exceptional stay. I had a hard time finding the drop box
Reviewed on Mar 6, 2026

Home2 Suites by Hilton St. Louis Downtown
1221 Locus Street St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $114 total per night from Mar 15 to Mar 16
$114 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center ...
Very good
Reviewed on Mar 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Roxana with star-rating
Check Roxana Hotels by Star Rating

4 Star Hotels
58 properties
Frequently asked questions
Recent Roxana hotel reviews by fellow wanderers

21C Museum Hotel St Louis
4 out of 5
Posted 2 hours ago
Travelocity Verified Review
"Unique hotel, would stay again "
A verified traveler stayed at 21C Museum Hotel St Louis
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