Find and compare 2 Star hotels in Southeast Missouri

Name: Quality Inn Cape Girardeau North
Price range: $75 total
Rating: 7.2

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Top Southeast Missouri 2 Star hotels

Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St Farmington MO

Fully refundableReserve now, pay when you stay

$60 nightly

$65 total

May 25 - May 26

Total with taxes and fees

This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

8/10 Very Good! (1,001 reviews)

I get it is cheap, but It shouldn’t small like feet. The room smelled bad, the hallway also, the walls are thin u can hear any noise. Never again

Reviewed on Apr 26, 2026

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

Fully refundableReserve now, pay when you stay

$102 nightly

$115 total

May 17 - May 18

Total with taxes and fees

This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...

9/10 Wonderful! (552 reviews)

I love that they welcome pets and then most of the staff love on our dogs when we are there. The breakfast was not as good as usual but I am a picky eater so that could have just been me so I don’t want to ding their ratings based on that - not many places provide a free hot breakfast! This is the ...

Reviewed on Apr 29, 2026

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

Fully refundableReserve now, pay when you stay

$72 nightly

$81 total

May 17 - May 18

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...

9/10 Wonderful! (1,000 reviews)

When i arrived, guest service wasn’t nice to me. Donya worked through her issues with me to get me out of her face. I was nice to her either way. I just wanted a pleasant stay.

Reviewed on Apr 28, 2026

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

Fully refundableReserve now, pay when you stay

$65 nightly

$69 total

Apr 30 - May 1

Total with taxes and fees

This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed ...

8/10 Very Good! (1,000 reviews)

Floors and windows in room were dirty.. terrible lighting TERRIBLE!!!

Reviewed on Apr 27, 2026

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

Fully refundableReserve now, pay when you stay

$65 nightly

$74 total

Apr 30 - May 1

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

Fully refundable

$105 nightly

$118 total

May 17 - May 18

Total with taxes and fees

A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...

9.4/10 Exceptional! (1,001 reviews)

The room that we got the window shades were broken.

Reviewed on Apr 24, 2026

Holiday Inn Express & Suites Perryville by IHG

2020 Jefferson St Perryville MO

$101 nightly

$116 total

May 3 - May 4

Total with taxes and fees

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...

9.2/10 Wonderful! (580 reviews)

Reviewed on Apr 22, 2026

Comfort Inn Festus - St Louis South

1303 Veterans Blvd Festus MO

Fully refundable

$78 nightly

$88 total

May 10 - May 11

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...

7.8/10 Good! (942 reviews)

Did have breakfast, coffee was good.

Reviewed on Apr 25, 2026

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

Fully refundableReserve now, pay when you stay

$80 nightly

$91 total

May 20 - May 21

Total with taxes and fees

This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...

8.4/10 Very Good! (1,000 reviews)

Bathroom had pee stains around the toilet. On their add they use a picture of a large beautiful room where you check in. Not This motel is old and run down.

Reviewed on Apr 22, 2026

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

Fully refundableReserve now, pay when you stay

$67 nightly

$75 total

May 5 - May 6

Total with taxes and fees

An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like English breakfast and WiFi in public ...

7.2/10 Good! (734 reviews)

Parking was great! Breakfast needs alot of improvement. But all together was a great experience!

Reviewed on Apr 27, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

2 Star Hotels Southeast Missouri

Looking to break out of your routine for some much needed rest and relaxation? Or maybe you’ve already decided it’s time for a trip and are trying to find affordable hotels in Southeast Missouri that won’t bust your travel budget?

Southeast Missouri 2 star hotels will give you everything you need to enjoy the city like a local, saving a ton of money so you can hit all the hot spots in town.

Have a delicious breakfast at your hotel to fuel up for your day of sightseeing, then enjoy amenities like fresh towels and linens, as well as a nice hot shower to unwind after a busy day of experiencing everything the city has to offer.

As you explore a new locale, or one you love to visit over and over, you can rest easy knowing you’re staying in a great hotel that lets you discover Southeast Missouri and welcomes you back to a clean, comfortable room at night.

Browse Travelocity’s wide selection of 2 star hotels in Southeast Missouri and find one that’s perfectly priced and places you next to all the best activities and sights. The town is your oyster, and we can help you seek out its secrets while sticking to your budget.

Recent Southeast Missouri hotel reviews by fellow wanderers

Hampton Inn Sikeston

5 out of 5

Posted 4 hours ago

Travelocity Verified Review

"I love that they welcome pets and then most of the staff love on our dogs when we are there. The breakfast was not as good as usual but I am a picky eater so that could have just been me so I don’t want to ding their ratings based on that - not many places provide a free hot breakfast! This is the only hotel we will stay in when we visit family in Sikeston. "

A verified traveler stayed at Hampton Inn Sikeston