Southeast Missouri , MO Pet Friendly Hotels
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Top Southeast Missouri Pet Friendly Hotels
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Feb 3 to Feb 4
$103 total
Feb 3 - Feb 4
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.4/10 Exceptional! (1,003 reviews)
As always it was a perfect visit
Reviewed on Jan 19, 2026
Pear Tree Inn Sikeston
2602 E Malone Avenue Sikeston MO
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.2/10 Wonderful! (1,001 reviews)
Clean room. Nice facilities. Pool is half inside half outside so even though it was heated it was still very cold
Reviewed on Jan 19, 2026
Drury Inn & Suites Poplar Bluff
2220 N Westwood Blvd Poplar Bluff MO
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.2/10 Wonderful! (985 reviews)
Very comfortable beds, quiet, and good breakfast. My third time to stay. Great place for the price.
Reviewed on Jan 17, 2026
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St Cape Girardeau MO
Free WiFi in public areas and express check-out are available at this hotel. Staff at the 24-hour front desk can provide around-the-clock assistance.
8.8/10 Excellent! (1,003 reviews)
Clean, comfortable room with nice shower
Reviewed on Jan 9, 2026
Microtel Inn & Suites by Wyndham Sainte Genevieve
21958 Hwy 32 Ste Genevieve MO
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Jan 29 to Jan 30
$75 total
Jan 29 - Jan 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
8.6/10 Excellent! (615 reviews)
The Microtel is a nice, relatively inexpensive place to stay in Ste. Genevieve. Breakfast options are somewhat limited. Overall, it is a very good value for the price.
Reviewed on Jan 20, 2026
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $60 total per night from Jan 27 to Jan 28
$60 total
Jan 27 - Jan 28
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed ...
7.8/10 Good! (1,000 reviews)
Friendly staff and the room was clean.
Reviewed on Jan 19, 2026
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
1001 Veterans Blvd Festus MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $107 total per night from Feb 1 to Feb 2
$107 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.8/10 Good! (906 reviews)
Clean room
Reviewed on Jan 12, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Feb 1 to Feb 2
$72 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
7.2/10 Good! (1,000 reviews)
Everything was excellent
Reviewed on Jan 18, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Pet Friendly Hotel in Southeast Missouri
Southeast Missouri hotels essential information
Accommodation | 622 hotels |
|---|---|
Lowest Price | $60 |
Highest Price | $107 |
Popular hotels | Motel 6 Poplar Bluff, MO, Microtel Inn & Suites by Wyndham Sainte Genevieve, La Quinta Inn & Suites by Wyndham Festus - St. Louis South, Drury Inn & Suites Sikeston, MO, Pear Tree Inn Sikeston, Drury Inn & Suites Poplar Bluff, Days Inn and Suites by Wyndham Sikeston, Pear Tree Inn Cape Girardeau Near the Medical Center |
Recent Southeast Missouri hotel reviews by fellow wanderers
Drury Inn & Suites Jackson MO
5 out of 5
Posted 6 days ago
Travelocity Verified Review
"Excellent room, excellent staff. Breakfast and dinner were great. Hot tub was not working and the pool was a bit cold, but I knew this before I reserved the room because it was on the website that the pool area was having maintenance done Cleanliness of the room was outstanding."
A verified traveler stayed at Drury Inn & Suites Jackson MO
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