Southeast Missouri , MO Pet Friendly Hotels
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Southeast Missouri Pet Friendly Hotels
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Dec 14 to Dec 15
$103 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.4/10 Exceptional! (1,002 reviews)
Clean big room, great staff
Reviewed on Nov 30, 2025
Pear Tree Inn Sikeston
2602 E Malone Avenue Sikeston MO
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $86 total per night from Dec 14 to Dec 15
$86 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.2/10 Wonderful! (1,000 reviews)
Check-in took only a few minutes and staff was courteous and efficient. All was explained clearly and efficiently. Room was clean and well maintained. I did not take part in the 5:30 pm event or attend breakfact, so I cannot comment on these amenities. Everything else was wonderful.
Reviewed on Nov 25, 2025
Drury Inn & Suites Poplar Bluff
2220 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Dec 14 to Dec 15
$106 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.2/10 Wonderful! (959 reviews)
Staff was fantastic, especially John. All very friendly, helpful, & courteous.
Reviewed on Dec 8, 2025
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Dec 14 to Dec 15
$79 total
Dec 14 - Dec 15
Total with taxes and fees
Free WiFi in public areas and express check-out are available at this hotel. Staff at the 24-hour front desk can provide around-the-clock assistance.
8.8/10 Excellent! (1,005 reviews)
Room could have been cleaner and no cups for coffee. Staff at front desk OUTSTANDING.
Reviewed on Dec 6, 2025
Microtel Inn & Suites by Wyndham Sainte Genevieve
21958 Hwy 32 Ste Genevieve MO
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $83 total per night from Dec 14 to Dec 15
$83 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
8.6/10 Excellent! (610 reviews)
very clean
Reviewed on Nov 29, 2025
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $80 total per night from Dec 11 to Dec 12
$80 total
Dec 11 - Dec 12
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed ...
7.8/10 Good! (1,000 reviews)
Love the updated rooms and the vending area.
Reviewed on Dec 6, 2025
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
1001 Veterans Blvd Festus MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $112 total per night from Dec 14 to Dec 15
$112 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
7.8/10 Good! (883 reviews)
Everything was
Reviewed on Nov 30, 2025
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Dec 14 to Dec 15
$72 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
7.2/10 Good! (1,001 reviews)
Very nice room, staff was nice. The tv room and bathroom were cold. No heat in those rooms.
Reviewed on Dec 7, 2025
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Pet Friendly Hotel in Southeast Missouri
Southeast Missouri hotels essential information
Accommodation | 618 hotels |
|---|---|
Lowest Price | $72 |
Highest Price | $112 |
Popular hotels | Motel 6 Poplar Bluff, MO, Microtel Inn & Suites by Wyndham Sainte Genevieve, La Quinta Inn & Suites by Wyndham Festus - St. Louis South, Drury Inn & Suites Sikeston, MO, Pear Tree Inn Sikeston, Drury Inn & Suites Poplar Bluff, Days Inn and Suites by Wyndham Sikeston, Pear Tree Inn Cape Girardeau Near the Medical Center |
Recent Southeast Missouri hotel reviews by fellow wanderers
Drury Plaza Hotel Cape Girardeau Conference Center
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Beds were great. Very clean all around. Very nice breakfast with glutten free bread for my wife.
"
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Explore More Ways to Travel with Travelocity
- Des Arc Hotels
- 5 Star Hotels in Annapolis
- Apartments in Annapolis
- B&B in Annapolis
- Cabins in Annapolis
- Cottages in Annapolis
- Cheap Hotels in Annapolis
- Hotels with Bar in Annapolis
- Annapolis Hotels
- Lodges in Annapolis
- Vacation Homes in Annapolis
- B&B in Lesterville
- Cabins in Lesterville
- Lesterville Hotels
- Hotels near Fort Davidson State Historic Site
- 4 Star Hotels in Arcadia
- B&B in Arcadia
- Arcadia Hotels
- Lodges in Arcadia
- Rv Parks in Arcadia
- Lodges in Patterson
- B&B in Ironton
- Cabins in Ironton
- Hotels with Hot Tubs in Ironton
- Hotel Wedding Venues Hotels in Ironton
- Ironton Hotels
- Lodges in Ironton
- Motels in Ironton
- Vacation Homes in Ironton
- Rv Parks in Ironton
- Hotels near K Bridge Recreation Area
- Pet Friendly Hotels in Van Buren
- Hotels with a Lazy River in St. Louis
- Hotels near Silver Mine Recreation Area
- Hotels near Walnut Hollow Lake
- Cabins in Arcadia Valley Station
- Adults Only Resorts & in Farmington
- Casino Resorts & in Farmington
- Cheap Hotels in Farmington
- Kid Friendly Hotels in Farmington
- Golf Resorts & in Farmington
- Hotels with Pools in Farmington
- Hotels with Bar in Farmington
- Hotels with Hot Tubs in Farmington
- Hotels with an Indoor Pool in Farmington
- Pet Friendly Hotels in Farmington
- Romantic Getaways & Hotels in Farmington
- Ski Resorts and in Farmington
- Spa Resorts & in Farmington
- Hotel Wedding Venues Hotels in Farmington
- Winery Hotels in Farmington
- Hotels near Millstream Gardens Conservation Area
- B&B in Pilot Knob
- Cabins in Pilot Knob
- Cottages in Pilot Knob
- Hotels with Pools in Pilot Knob
- Lodges in Pilot Knob
- Motels in Pilot Knob
- Vacation Homes in Pilot Knob
- Cheap Hotels in Wappapello
- Apartments in Piedmont
- Cabins in Piedmont
- Condos in Piedmont
- Cheap Hotels in Piedmont
- Hotels with Pools in Piedmont
- Pet Friendly Hotels in Piedmont
- Piedmont Hotels
- Lodges in Piedmont
- Motels in Piedmont
- Vacation Homes in Piedmont
- Rv Parks in Piedmont
- Cobalt Hotels
- Hotels near Arcadia Valley Golf Club
- Hotels near Taum Sauk Mountain State Park
- Hotels near Madison County Courthouse
- Greenville Hotels
- Convention Center Hotels in Bonne Terre
- Hotels with Hot Tubs in Bonne Terre
- Pet Friendly Hotels in Bonne Terre
- Farmstay in Fredericktown
- Apartments in Fredericktown
- B&B in Fredericktown
- Cabins in Fredericktown
- Cottages in Fredericktown
- Hotels with Pools in Fredericktown
- Pet Friendly Hotels in Fredericktown
- Fredericktown Hotels
- Motels in Fredericktown
- Vacation Homes in Fredericktown