Cheap Flights to Southeast Missouri from $28

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How Much Does it Cost To Fly To Southeast Missouri?

The cheapest prices found with in the last 7 days for return flights were $60 and $28 for one-way flights to Southeast Missouri for the period specified. Prices and availability are subject to change. Additional terms apply

Tue, Oct 6 - Thu, Oct 15
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$60 Roundtrip, found 1 day ago
$60
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, Oct 6 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Oct 15, priced at $60 found 1 day ago
OriginDestinationTravel DatesFlights From*
MSYWest PaducahJune 23 to June 30$280
EWRWest PaducahAugust 15 to August 22$294
MSPWest PaducahSeptember 3 to September 7$294
SATWest PaducahJune 18 to June 21$386
EWRMarionJuly 9 to July 10$391
MSPMarionJune 21 to June 22$552
LAXScott CityJuly 17 to July 22$587
LAXMarionJune 18 to June 22$759
MSYMarionAugust 2 to August 4$1,209
DCAMarionJune 16 to June 20$1,379
CMHScott CityJune 25 to June 29$1,396
BWIScott CityJune 30 to July 7$1,412
STLScott CityJune 15 to June 22$1,437
SATScott CityJune 18 to June 21$1,730
BWIMarionJune 18 to June 21$2,159
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
LAXSt. LouisJune 6 to June 27$344
EWRSt. LouisJune 7 to June 11$351
CMHSt. LouisJune 6 to June 15$415
BWISt. LouisJune 7 to June 15$519
DCASt. LouisJune 7 to June 15$519
MSPSt. LouisJune 6 to June 7$617
MSYSt. LouisJune 6 to June 16$1,204
LAXWest PaducahJune 7 to June 11$1,291
SATSt. LouisJune 7 to June 9$1,462
MCISt. LouisJune 7 to June 12$1,645
BWIScott CityJune 7 to June 9$1,938
*Prices include taxes and fees

Southeast Missouri Flight Information

Traveling to
Southeast Missouri
Lowest Price
$60
Number of Airlines Serving
Airlines Serving
Frontier Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Southeast Missouri Accommodation Deals

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
$75 nightly
The price is $84 total per night from Jun 9 to Jun 10
$84 total
Jun 9 - Jun 10
Total with taxes and fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,000 reviews)
"Nice clean hotel, reservation was for queen bed actual bed in room was double. No coffee maker in room detracted from stay."

Reviewed on May 29, 2026

Opens in a new windowMotel 6 Poplar Bluff, MO
Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington

2 out of 5
930 Valley Creek Dr Farmington MO
$62 nightly
The price is $68 total per night from Jun 14 to Jun 15
$68 total
Jun 14 - Jun 15
Total with taxes and fees
Book a stay at this business-friendly motel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (650 reviews)
"This is my new place whenever I’m in town."

Reviewed on May 24, 2026

Opens in a new windowSuper 8 by Wyndham Farmington
Super 8 by Wyndham Pevely

Super 8 by Wyndham Pevely

2 out of 5
1711 Highway Z Pevely MO
$75 nightly
The price is $86 total per night from Jun 8 to Jun 9
$86 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
Opens in a new windowSuper 8 by Wyndham Pevely
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Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from Jun 8 to Jun 9
$81 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,002 reviews)
"Excellent breakfast and quiet night of rest"

Reviewed on Jun 3, 2026

Opens in a new windowPear Tree Inn Cape Girardeau West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Southeast Missouri

Super 8 by Wyndham Pevely

Super 8 by Wyndham Pevely

2 out of 5
1711 Highway Z Pevely MO
$75 nightly
The price is $86 total per night from Jun 8 to Jun 9
$86 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
Opens in a new windowSuper 8 by Wyndham Pevely
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
$75 nightly
The price is $84 total per night from Jun 9 to Jun 10
$84 total
Jun 9 - Jun 10
Total with taxes and fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,000 reviews)
"Nice clean hotel, reservation was for queen bed actual bed in room was double. No coffee maker in room detracted from stay."

Reviewed on May 29, 2026

Opens in a new windowMotel 6 Poplar Bluff, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
$71 nightly
The price is $81 total per night from Jun 7 to Jun 8
$81 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,002 reviews)
"Ll"

Reviewed on May 25, 2026

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
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Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Cape Girardeau MO
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Riverfront Park and eDen Spa & Salon are located ...
10/10 Exceptional! (225 reviews)
"Amazing place to stay at the Cape!"

Reviewed on Apr 12, 2026

Get rates
Opens in a new windowHistorical 'Kage House' Short Term Rental located in "Old Town Cape"
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Southeast Missouri

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
$111 nightly
The price is $128 total per night from Jun 8 to Jun 9
$128 total
Jun 8 - Jun 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,005 reviews)
"The ladies at the desk and in the dinner area were great!"

Reviewed on May 31, 2026

Opens in a new windowDrury Inn & Suites Sikeston, MO
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
$91 nightly
The price is $104 total per night from Jun 14 to Jun 15
$104 total
Jun 14 - Jun 15
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,004 reviews)
"Very convenient and staff was great."

Reviewed on Jun 2, 2026

Opens in a new windowBest Western Plus Sikeston I-55
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night from Jun 21 to Jun 22
$102 total
Jun 21 - Jun 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,007 reviews)
"We have never had a bad experience at a Drury Inn, and this stay was no exception. The hotel and room was clean and comfortable. We enjoyed the happy hour dinner and drinks special they host every evening, and the included buffet breakfast is better than any other hotel we’ve been at."

Reviewed on Jun 4, 2026

Opens in a new windowDrury Inn & Suites Cape Girardeau
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Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 out of 5
2904 Old Orchard Rd Jackson MO
$93 nightly
The price is $101 total per night from Jun 18 to Jun 19
$101 total
Jun 18 - Jun 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
Opens in a new windowComfort Suites Jackson-Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Southeast Missouri Flight and Hotel Packages

Southeast Missouri flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Price was $416, price is now $330 per person
$330
per person
Jul 18 - Jul 20
found 5 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
Homewood Suites by Hilton St. Louis Westport

Homewood Suites by Hilton St. Louis Westport

3 out of 5
Save 100% on your flight
Price was $1,303, price is now $1,003 per person
$1,003
per person
Jul 14 - Jul 19
found 20 hours ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO

3 out of 5
Price was $1,066, price is now $829 per person
$829
per person
Jul 12 - Jul 18
found 1 day ago
Roundtrip flight included
New York (NYC) to St. Louis (STL)
Don't see what you're looking for?
See all available trips from Atlanta to Southeast Missouri
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Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

Frequently asked questions

How much is the cheapest flight to Southeast Missouri?
A roundtrip flight to Southeast Missouri cost as little as $60 over the last seven days. Once you've chosen your travel dates, we'll help you find an amazing deal. This price was available on Travelocity for flights to Southeast Missouri departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly to Southeast Missouri?
Be sure to leave October empty in your calendar, because it's the most affordable month to travel to Southeast Missouri. That's based on Travelocity's direct flight demand from January to December last year. With the cash you save, you can go on a spending spree, go for a fancy dinner or whatever makes you happy.
How can I check my flight status to Southeast Missouri?
Make the most of Travelocity's handy portal, Trips. You'll find just about everything related to your flight to Southeast Missouri here, including details about flight status, gate numbers and more. Look for Trips at the top of the Travelocity homepage. Create your free account and get the answers you need. Or you can access your itinerary while you're on the go and get real-time travel updates through the Travelocity app. You'll find all your itineraries in one place, making it a cinch to share details with any members of your family flying with you.
How do I find the best deals on flights to Southeast Missouri?
Being flexible with your dates is one of the best ways to snag an awesome deal. Travelocity makes it a cinch to find your perfect fare through the "Flexible dates" feature. First, search for your Southeast Missouri flight, then compare prices for surrounding dates by hitting the Flexible dates box above. Booking in advance and avoiding peak travel periods are other steps you can take. In the last seven days, the lowest price for a return flight to Southeast Missouri was $60. This price was available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Why should I book my flight to Southeast Missouri with Travelocity?
If you're looking for cheap flights to Southeast Missouri, you'll discover some tempting deals with Travelocity. From cheap family flights with low-cost airlines to flexible tickets, we can help you. Enjoy a worry-free trip with our 24/7 customer support, Price Match Guarantee and free cancellations with most hotels. Start packing your bags and get ready to jump on a plane to this interesting destination.
How much is a flight to Southeast Missouri on average?
Airfares for roundtrip flights to Southeast Missouri were priced between $60 and $2,159 in the last seven days. The minute you spot a good deal, snap it up and get ready for your dream getaway with Travelocity. These prices were available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What can I expect on a flight to Southeast Missouri?
Factors like who you're flying with and where you're departing from will mostly determine what you'll be offered on your trip. Chances are you'll find all kinds of flights to Southeast Missouri, from cheap flights for family vacations to premium fares. Warm meals, entertainment and games for the little ones are usually what most airlines offer on long-haul flights.

Plane Tickets To Southeast Missouri

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Southeast Missouri. Browse through our inventory to explore a wide range of cheap flights to Southeast Missouri to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Southeast Missouri as you anxiously await to exit the plane and explore what Southeast Missouri has to offer. Considering all the amazing local food and culture in Southeast Missouri, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Southeast Missouri to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Southeast Missouri without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Southeast Missouri with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Southeast Missouri today!

Explore More Ways to Travel with Travelocity

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.