Cheap Flights to Southeast Missouri from $35
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How Much Does it Cost To Fly To Southeast Missouri?
The cheapest prices found with in the last 7 days for return flights were $58 and $35 for one-way flights to Southeast Missouri for the period specified. Prices and availability are subject to change. Additional terms apply
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$58 Roundtrip, found 5 hours ago
$58
Roundtrip
found 5 hours ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| BWI | St. Louis | May 12 to May 16 | $164 |
| LAX | St. Louis | May 19 to June 3 | $190 |
| DCA | St. Louis | May 24 to May 26 | $210 |
| STL | Marion | May 12 to May 13 | $268 |
| SAT | West Paducah | May 17 to May 23 | $326 |
| DCA | West Paducah | May 7 to May 12 | $326 |
| LAX | West Paducah | June 1 to June 8 | $362 |
| MSP | Marion | May 20 to May 23 | $467 |
| MSY | Marion | May 5 to May 7 | $561 |
| EWR | Scott City | July 11 to July 19 | $606 |
| MSP | Scott City | May 1 to May 4 | $690 |
| MCI | Scott City | May 3 to May 6 | $749 |
| LAX | Scott City | April 30 to May 3 | $774 |
| LAX | Marion | May 16 to May 19 | $1,020 |
| BWI | Scott City | May 7 to May 10 | $1,603 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| EWR | St. Louis | April 24 to May 6 | $230 |
| BWI | St. Louis | April 25 to April 29 | $246 |
| LAX | St. Louis | April 26 to May 4 | $296 |
| CMH | St. Louis | April 25 to April 26 | $374 |
| MSP | St. Louis | April 25 to April 27 | $426 |
| DCA | St. Louis | April 26 to April 27 | $493 |
| MSY | St. Louis | April 24 to April 26 | $583 |
| MCI | St. Louis | April 25 to April 28 | $708 |
| MSY | Scott City | April 24 to April 26 | $799 |
| SAT | St. Louis | April 24 to April 27 | $1,026 |
Southeast Missouri Flight Information
Traveling to | Southeast Missouri |
|---|---|
Lowest Price | $58 |
Number of Airlines Serving | |
Airlines Serving | Frontier Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Southeast Missouri Accommodation Deals
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
$73 nightly
The price is $77 total per night from Apr 22 to Apr 23
$77 total
Apr 22 - Apr 23
Total with taxes and fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,003 reviews)
Clean room, easy parking, loved that our room had seat in the shower. Made it easier for me while recovering from ankle surgery. Always love motel 6 for being pet friendly and having a 24 hour lobby. Makes a world of difference while traveling.
Reviewed on Apr 17, 2026
Super 8 by Wyndham Farmington
930 Valley Creek Dr Farmington MO
$60 nightly
The price is $65 total per night from May 7 to May 8
$65 total
May 7 - May 8
Total with taxes and fees
Book a stay at this business-friendly motel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (638 reviews)
Breakfast menu was a little limited. Clean room. Staff great! Air condition and heat perfect. Better than what I consider it's price competitors to be. In today's high tech age, a few more electrical receptacles would be nice, but that's the case in most hotel/motels in this price range.
Reviewed on Mar 31, 2026
Super 8 by Wyndham Pevely
1711 Highway Z Pevely MO
$76 nightly
The price is $87 total per night from May 3 to May 4
$87 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
5.6/10 (846 reviews)
Horrible dirty needs cleaned everywhere smells like mold and staff is rude
Reviewed on Apr 13, 2026
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Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from May 17 to May 18
$81 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,002 reviews)
Breakfast was hot and manned by a friendly staff member. Room was clean and met my needs.
Reviewed on Apr 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Southeast Missouri
Super 8 by Wyndham Pevely
1711 Highway Z Pevely MO
$76 nightly
The price is $87 total per night from May 3 to May 4
$87 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
5.6/10 (846 reviews)
Horrible dirty needs cleaned everywhere smells like mold and staff is rude
Reviewed on Apr 13, 2026
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
$73 nightly
The price is $77 total per night from Apr 22 to Apr 23
$77 total
Apr 22 - Apr 23
Total with taxes and fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,003 reviews)
Clean room, easy parking, loved that our room had seat in the shower. Made it easier for me while recovering from ankle surgery. Always love motel 6 for being pet friendly and having a 24 hour lobby. Makes a world of difference while traveling.
Reviewed on Apr 17, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$61 nightly
The price is $70 total per night from Apr 26 to Apr 27
$70 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,000 reviews)
It had a clean room. Better than most hotels like this. The bathroom smelled like mold or mildew. And the lobby smelled of moth balls. Some of the sheets had black stuff on them. Not sure what it was. Air conditioning was cold.
Reviewed on Apr 12, 2026
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Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau MO
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Riverfront Park and eDen Spa & Salon are located ...
10/10 Exceptional! (224 reviews)
Great location, quality bedding and pillows, and other comfortable amenities for a short getaway in historic downtown Cape Girardeau. Excellent value!
Reviewed on Dec 15, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Southeast Missouri
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$97 nightly
The price is $112 total per night from Apr 27 to Apr 28
$112 total
Apr 27 - Apr 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,005 reviews)
👍
Reviewed on Apr 19, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
$77 nightly
The price is $88 total per night from Apr 26 to Apr 27
$88 total
Apr 26 - Apr 27
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,004 reviews)
The staff were all wonderful and the breakfast was good. Our room door was propped open when we arrived, which was kind of off-putting. Also, the property could use some upgrades. I think the bathtub was clean, just old so kind of dingy looking. The elevator was out of order.
Reviewed on Apr 20, 2026
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
$94 nightly
The price is $106 total per night from May 17 to May 18
$106 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,006 reviews)
Wonderful stay, very spacious room, clean, super comfortable beds, breakfast was delicious!
Reviewed on Apr 20, 2026
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Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd Jackson MO
$92 nightly
The price is $100 total per night from May 3 to May 4
$100 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (762 reviews)
It was way below average and was not a cheap property to stay at. Very dirty room, bathroom was disgusting. Breakfast was mediocre. Pool area was even dirty. Front desk clerk was also doing the breakfast area. Wore the same gloves from food area, to front desk, back to food area.
Reviewed on Apr 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Southeast Missouri Flight and Hotel Packages
Southeast Missouri flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Don't see what you're looking for?
See all available trips from Atlanta to Southeast Missouri
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Economy
Chevrolet Spark or similar
Compact
Ford Focus or similar
Midsize
Toyota Corolla or similar
SUV
Jeep Compass or similar
Frequently asked questions
Plane Tickets To Southeast Missouri
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When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Southeast Missouri to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Southeast Missouri without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Southeast Missouri with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Southeast Missouri today!
More Ways To Wander
Southeast Missouri Hotels
Find the perfect hotel after your flight
Southeast Missouri Vacation Rentals
Great Deals on alternative accommodations
Southeast Missouri Car Rentals
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Southeast Missouri Vacations
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Things to do in Southeast Missouri
Activities, attractions and tours
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