Cheap Flights to Southeast Missouri from $48

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How Much Does it Cost To Fly To Southeast Missouri?

The cheapest prices found with in the last 7 days for return flights were $77 and $48 for one-way flights to Southeast Missouri for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
DCASt. LouisDecember 17 to December 31$133
EWRSt. LouisOctober 31 to October 31$151
BWISt. LouisOctober 2 to October 6$156
LAXSt. LouisNovember 17 to November 19$160
CMHSt. LouisOctober 24 to October 30$164
EWRWest PaducahOctober 7 to October 16$424
BWIWest PaducahOctober 16 to October 20$444
DCAWest PaducahOctober 16 to October 20$448
DCAMarionDecember 18 to January 1$480
LAXMarionSeptember 26 to September 30$548
BWIMarionDecember 18 to January 2$549
LAXWest PaducahSeptember 27 to September 28$690
STLMarionNovember 14 to November 16$808
LAXScott CityOctober 17 to October 19$857
SATScott CitySeptember 25 to September 29$1,047
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
EWRSt. LouisSeptember 21 to September 25$178
LAXSt. LouisSeptember 21 to September 23$224
BWISt. LouisSeptember 21 to September 22$247
MSPSt. LouisSeptember 19 to September 21$252
MSYSt. LouisSeptember 19 to September 21$441
MCISt. LouisSeptember 19 to October 7$457
CMHSt. LouisSeptember 20 to October 2$474
DCASt. LouisSeptember 20 to September 29$642
SATSt. LouisSeptember 21 to September 25$841
MSPScott CitySeptember 19 to September 21$1,787
*Prices include taxes and fees

Southeast Missouri Flight Information

Traveling to
Southeast Missouri
Lowest Price
$77
Number of Airlines Serving
Airlines Serving
Frontier Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Southeast Missouri Accommodation Deals

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N, Poplar Bluff, MO
$79 nightly
The price is $83 total per night from Sep 17 to Sep 18
$83 total
Sep 17 - Sep 18
Total with taxes and fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,007 reviews)
"Fantastic staff, cleaning crew and it was a wonderful experience."

Reviewed on Sep 16, 2025

Opens in a new windowMotel 6 Poplar Bluff, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
$77 nightly
The price is $89 total per night from Sep 22 to Sep 23
$89 total
Sep 22 - Sep 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
"Easy check-in . Pleasant staff. Good experience."

Reviewed on Sep 9, 2025

Opens in a new windowPear Tree Inn Sikeston
Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington

2 out of 5
930 Valley Creek Dr, Farmington, MO
$58 nightly
The price is $66 total per night from Sep 17 to Sep 18
$66 total
Sep 17 - Sep 18
Total with taxes and fees
Book a stay at this business-friendly motel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (588 reviews)
"Location"

Reviewed on Sep 14, 2025

Opens in a new windowSuper 8 by Wyndham Farmington
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Super 8 by Wyndham Pevely

Super 8 by Wyndham Pevely

2 out of 5
1711 Highway Z, Pevely, MO
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
5.6/10 (826 reviews)
Adequate
"Hotel is in rough shape…but if you just need a place to sleep for the night it will fulfill that. Hotel needs a major revamping."

Reviewed on May 17, 2025

Opens in a new windowSuper 8 by Wyndham Pevely
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Southeast Missouri

Super 8 by Wyndham Pevely

Super 8 by Wyndham Pevely

2 out of 5
1711 Highway Z, Pevely, MO
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
5.6/10 (826 reviews)
Adequate
"Hotel is in rough shape…but if you just need a place to sleep for the night it will fulfill that. Hotel needs a major revamping."

Reviewed on May 17, 2025

Opens in a new windowSuper 8 by Wyndham Pevely
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N, Poplar Bluff, MO
$79 nightly
The price is $83 total per night from Sep 17 to Sep 18
$83 total
Sep 17 - Sep 18
Total with taxes and fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,007 reviews)
"Fantastic staff, cleaning crew and it was a wonderful experience."

Reviewed on Sep 16, 2025

Opens in a new windowMotel 6 Poplar Bluff, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
$63 nightly
The price is $72 total per night from Sep 21 to Sep 22
$72 total
Sep 21 - Sep 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,003 reviews)
"Spacious room"

Reviewed on Sep 13, 2025

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
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Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Cape Girardeau
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a water park, and laundry facilities. Popular attractions Riverfront Park and eDen Spa & Salon are ...
9.8/10 Exceptional! (168 reviews)
"Property location was perfect.Deck view was great.Very clean and comfortable place."

Reviewed on Jul 21, 2025

Opens in a new windowHistorical 'Kage House' Short Term Rental located in "Old Town Cape"
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Southeast Missouri

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
$90 nightly
The price is $103 total per night from Sep 21 to Sep 22
$103 total
Sep 21 - Sep 22
Total with taxes and fees
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,003 reviews)
"The bed was comfy. Food was delicious. Hot tub was relaxing. Staff was nice and helpful. Overall the hotel was very nice."

Reviewed on Sep 16, 2025

Opens in a new windowDrury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
$77 nightly
The price is $89 total per night from Sep 22 to Sep 23
$89 total
Sep 22 - Sep 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,000 reviews)
"Easy check-in . Pleasant staff. Good experience."

Reviewed on Sep 9, 2025

Opens in a new windowPear Tree Inn Sikeston
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
$84 nightly
The price is $96 total per night from Oct 12 to Oct 13
$96 total
Oct 12 - Oct 13
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,006 reviews)
"Very friendly staff"

Reviewed on Sep 16, 2025

Opens in a new windowBest Western Plus Sikeston
Save an average of 15% on thousands of hotels when you're signed in
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
$90 nightly
The price is $102 total per night from Oct 2 to Oct 3
$102 total
Oct 2 - Oct 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (990 reviews)
"Nice hotel clean"

Reviewed on Sep 9, 2025

Opens in a new windowDrury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Southeast Missouri Flight and Hotel Packages

Southeast Missouri flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
Hilton Garden Inn Chesterfield
The Cheshire
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Frequently asked questions

How much is the cheapest flight to Southeast Missouri?
A roundtrip flight to Southeast Missouri cost as little as $77 over the last seven days. Once you've chosen your travel dates, we'll help you find an amazing deal. This price was available on Travelocity for flights to Southeast Missouri departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly to Southeast Missouri?
Be sure to leave November empty in your calendar, because it's the most affordable month to travel to Southeast Missouri. That's based on Travelocity's direct flight demand from January to December last year. With the cash you save, you can go on a spending spree, go for a fancy dinner or whatever makes you happy.
How can I check my flight status to Southeast Missouri?
Make the most of Travelocity's handy portal, Trips. You'll find just about everything related to your flight to Southeast Missouri here, including details about flight status, gate numbers and more. Look for Trips at the top of the Travelocity homepage. Create your free account and get the answers you need. Or you can access your itinerary while you're on the go and get real-time travel updates through the Travelocity app. You'll find all your itineraries in one place, making it a cinch to share details with any members of your family flying with you.
How do I find the best deals on flights to Southeast Missouri?
Being flexible with your dates is one of the best ways to snag an awesome deal. Travelocity makes it a cinch to find your perfect fare through the "Flexible dates" feature. First, search for your Southeast Missouri flight, then compare prices for surrounding dates by hitting the Flexible dates box above. Booking in advance and avoiding peak travel periods are other steps you can take. In the last seven days, the lowest price for a return flight to Southeast Missouri was $77. This price was available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Why should I book my flight to Southeast Missouri with Travelocity?
If you're looking for cheap flights to Southeast Missouri, you'll discover some tempting deals with Travelocity. From cheap family flights with low-cost airlines to flexible tickets, we can help you. Enjoy a worry-free trip with our 24/7 customer support, Price Match Guarantee and free cancellations with most hotels. Start packing your bags and get ready to jump on a plane to this interesting destination.
How much is a flight to Southeast Missouri on average?
Airfares for roundtrip flights to Southeast Missouri were priced between $77 and $1,787 in the last seven days. The minute you spot a good deal, snap it up and get ready for your dream getaway with Travelocity. These prices were available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What can I expect on a flight to Southeast Missouri?
Factors like who you're flying with and where you're departing from will mostly determine what you'll be offered on your trip. Chances are you'll find all kinds of flights to Southeast Missouri, from cheap flights for family vacations to premium fares. Warm meals, entertainment and games for the little ones are usually what most airlines offer on long-haul flights.

Plane Tickets To Southeast Missouri

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Southeast Missouri. Browse through our inventory to explore a wide range of cheap flights to Southeast Missouri to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Southeast Missouri as you anxiously await to exit the plane and explore what Southeast Missouri has to offer. Considering all the amazing local food and culture in Southeast Missouri, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Southeast Missouri to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Southeast Missouri without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Southeast Missouri with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Southeast Missouri today!

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.