Cheap Flights to Sikeston from $28
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How Much Does it Cost To Fly To Sikeston?
The cheapest prices found with in the last 7 days for return flights were $56 and $28 for one-way flights to Sikeston for the period specified. Prices and availability are subject to change. Additional terms apply
MCO
Orlando Intl.
STL
Lambert-St. Louis Intl.
$56 Roundtrip, found 12 hours ago
$56
Roundtrip
found 12 hours ago
ORD
O'Hare Intl.
CGI
Cape Girardeau Municipal
$139 Roundtrip, found 2 days ago
$139
Roundtrip
found 2 days ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DEN | St. Louis | February 14 to February 21 | $56 |
| PHL | St. Louis | February 10 to February 18 | $128 |
| DFW | St. Louis | February 7 to February 7 | $130 |
| DFW | Scott City | January 28 to February 8 | $139 |
| JFK | St. Louis | February 4 to February 7 | $141 |
| LGA | St. Louis | February 7 to February 9 | $146 |
| LAX | St. Louis | February 7 to February 21 | $151 |
| SEA | St. Louis | February 16 to February 25 | $181 |
| EWR | West Paducah | February 5 to February 8 | $399 |
| DEN | Scott City | March 27 to March 30 | $399 |
| TPA | West Paducah | March 21 to March 22 | $525 |
| SEA | Scott City | February 8 to February 12 | $540 |
| SEA | West Paducah | March 8 to March 12 | $709 |
| FCO | St. Louis | February 26 to March 2 | $754 |
| ATL | West Paducah | January 29 to January 30 | $828 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| ATL | St. Louis | January 23 to January 26 | $81 |
| TPA | St. Louis | January 24 to January 24 | $81 |
| PHL | St. Louis | January 24 to January 26 | $217 |
| DEN | St. Louis | January 24 to January 25 | $234 |
| LGA | St. Louis | January 23 to January 26 | $238 |
| LGA | St. Louis | January 23 to January 26 | $238 |
| DFW | St. Louis | January 25 to January 26 | $239 |
| LAX | St. Louis | January 25 to January 28 | $290 |
| SEA | St. Louis | January 25 to January 26 | $321 |
| EWR | West Paducah | January 24 to February 4 | $541 |
| ATL | West Paducah | January 23 to January 25 | $625 |
| FCO | St. Louis | January 25 to February 13 | $845 |
Sikeston Flight Information
Traveling to | Sikeston |
|---|---|
Lowest Price | $56 |
Number of Airlines Serving | |
Airlines Serving | Frontier Airlines, Contour Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Sikeston Accommodation Deals
Pear Tree Inn Sikeston
2602 E Malone Avenue Sikeston MO
$75 nightly
The price is $86 total per night from Jan 25 to Jan 26
$86 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,002 reviews)
The staff was very welcoming and helpful. Our room was very clean and comfortable with lots of amenities. The breakfast was delicious with a wide variety of foods to choose from and the coffee was very good. We did not take advantage of the pool.
Reviewed on Jan 14, 2026
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$71 nightly
The price is $80 total per night from Jan 22 to Jan 23
$80 total
Jan 22 - Jan 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
The room was spacious, wonderful king size bed and the room was spotless.st
Reviewed on Jan 13, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$63 nightly
The price is $72 total per night from Jan 25 to Jan 26
$72 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,000 reviews)
It was nice a hotel have to come back sometime
Reviewed on Jan 9, 2026
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
$91 nightly
The price is $103 total per night from Jan 25 to Jan 26
$103 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,000 reviews)
Very nice room. There was a little noise from other rooms or perhaps from the hallways. The breakfast was very good.
Reviewed on Jan 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Sikeston
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$63 nightly
The price is $72 total per night from Jan 25 to Jan 26
$72 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,000 reviews)
It was nice a hotel have to come back sometime
Reviewed on Jan 9, 2026
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau MO
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a water park, and laundry facilities. Popular attractions Riverfront Park and eDen Spa & Salon are ...
9.8/10 Exceptional! (173 reviews)
Great location, quality bedding and pillows, and other comfortable amenities for a short getaway in historic downtown Cape Girardeau. Excellent value!
Reviewed on Dec 15, 2025
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St Cape Girardeau MO
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,003 reviews)
Clean, comfortable room with nice shower
Reviewed on Jan 9, 2026
Save an average of 15% on thousands of hotels when you're signed in
Quality Inn
2011 North Kingshighway Cape Girardeau MO
$60 nightly
The price is $68 total per night from Feb 3 to Feb 4
$68 total
Feb 3 - Feb 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (691 reviews)
The room was clean and nice. The breakfast was really good.
Reviewed on Dec 28, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Sikeston
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$94 nightly
The price is $108 total per night from Jan 25 to Jan 26
$108 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,004 reviews)
Good
Reviewed on Jan 14, 2026
Pear Tree Inn Sikeston
2602 E Malone Avenue Sikeston MO
$75 nightly
The price is $86 total per night from Jan 25 to Jan 26
$86 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,002 reviews)
The staff was very welcoming and helpful. Our room was very clean and comfortable with lots of amenities. The breakfast was delicious with a wide variety of foods to choose from and the coffee was very good. We did not take advantage of the pool.
Reviewed on Jan 14, 2026
Best Western Plus Sikeston
120 S Interstate Drive Sikeston MO
$71 nightly
The price is $81 total per night from Jan 25 to Jan 26
$81 total
Jan 25 - Jan 26
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,007 reviews)
The breakfast menu was fresh except for some of the Half and Half creamer was curdled, spoiled. And the coffee was luke warm.
Reviewed on Jan 12, 2026
Save an average of 15% on thousands of hotels when you're signed in
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night from Jan 22 to Jan 23
$102 total
Jan 22 - Jan 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (999 reviews)
Loved the happy hour, and pet friendly & shower.
Reviewed on Jan 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Sikeston Flight and Hotel Packages
Sikeston flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Need a Car For After Your Flight?
Special
Saint Ann, Missouri, USA
$38
$104 total
found 1 day ago
Compact
Saint Ann, Missouri, USA
$39
$108 total
found 1 day ago
Economy
Saint Ann, Missouri, USA
$39
$108 total
found 1 day ago
Midsize
Saint Ann, Missouri, USA
$41
$112 total
found 1 day ago
Frequently asked questions
Plane Tickets To Sikeston
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