Cheap Flights to Sikeston from $41
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How Much Does it Cost To Fly To Sikeston?
The cheapest prices found with in the last 7 days for return flights were $52 and $41 for one-way flights to Sikeston for the period specified. Prices and availability are subject to change. Additional terms apply
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$52 Roundtrip, found 6 days ago
$52
Roundtrip
found 6 days ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DEN | St. Louis | January 1 to January 4 | $84 |
| DAL | St. Louis | December 4 to December 5 | $117 |
| PHL | St. Louis | December 14 to December 16 | $216 |
| SEA | St. Louis | December 4 to December 9 | $221 |
| LGA | St. Louis | December 1 to December 2 | $257 |
| LGA | St. Louis | December 1 to December 2 | $257 |
| DFW | Scott City | November 4 to November 8 | $258 |
| LAX | St. Louis | December 16 to December 22 | $290 |
| DFW | West Paducah | October 29 to November 14 | $367 |
| LAX | West Paducah | October 26 to October 31 | $503 |
| ATL | Scott City | October 29 to November 5 | $611 |
| LAX | Scott City | December 9 to January 3 | $692 |
| FCO | St. Louis | November 23 to November 30 | $956 |
| DEN | Scott City | December 12 to January 1 | $1,278 |
| JFK | Scott City | December 23 to January 2 | $1,381 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| TTN | St. Louis | October 24 to December 4 | $328 |
| DFW | St. Louis | October 23 to October 26 | $333 |
| TPA | St. Louis | October 24 to October 28 | $385 |
| DEN | St. Louis | October 25 to October 28 | $409 |
| SEA | St. Louis | October 25 to October 28 | $417 |
| LAX | St. Louis | October 25 to October 28 | $440 |
| EWR | St. Louis | October 23 to October 25 | $511 |
| LAX | West Paducah | October 24 to October 31 | $514 |
| DFW | Scott City | October 25 to October 28 | $523 |
| LGA | St. Louis | October 24 to October 27 | $524 |
| ATL | St. Louis | October 24 to October 31 | $934 |
Sikeston Flight Information
Traveling to | Sikeston |
|---|---|
Lowest Price | $52 |
Number of Airlines Serving | |
Airlines Serving | Frontier Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Sikeston Accommodation Deals
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from Oct 25 to Oct 26
$81 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,006 reviews)
"Stayed here for a long weekend motorcycle trip. The hotel is conveniently located near many shopping and dining choices. The room was basic but clean and quiet, and lots of channels on the tv! Staff were super friendly and helpful. I will definitely stay here again the next time I am in Cape ..."
Reviewed on Oct 19, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$66 nightly
The price is $76 total per night from Nov 1 to Nov 2
$76 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
$99 nightly
The price is $113 total per night from Nov 19 to Nov 20
$113 total
Nov 19 - Nov 20
Total with taxes and fees
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
Save an average of 15% on thousands of hotels when you're signed in
Eagle Inn Charleston
2811 East Marshall Street Charleston MO
$66 nightly
The price is $74 total per night from Oct 20 to Oct 21
$74 total
Oct 20 - Oct 21
Total with taxes and fees
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
6.6/10 (107 reviews)
"Don’t go here if you’re a single woman traveling alone. I did not feel save even with my dog."
Reviewed on Aug 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Sikeston
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$66 nightly
The price is $76 total per night from Nov 1 to Nov 2
$76 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau MO
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Riverfront Park and eDen Spa & Salon are located ...
10/10 Exceptional! (229 reviews)
"Great location - very clean and well stocked with all essentials. Will stay again"
Reviewed on Sep 28, 2026
Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
$59 nightly
The price is $67 total per night from Nov 1 to Nov 2
$67 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
Save an average of 15% on thousands of hotels when you're signed in
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$94 nightly
The price is $108 total per night from Oct 25 to Oct 26
$108 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Sikeston
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$94 nightly
The price is $108 total per night from Oct 25 to Oct 26
$108 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
$80 nightly
The price is $91 total per night from Nov 8 to Nov 9
$91 total
Nov 8 - Nov 9
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
$90 nightly
The price is $102 total per night from Oct 25 to Oct 26
$102 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
Save an average of 15% on thousands of hotels when you're signed in
Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd Jackson MO
$76 nightly
The price is $82 total per night from Nov 9 to Nov 10
$82 total
Nov 9 - Nov 10
Total with taxes and fees
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8/10 Very Good! (784 reviews)
"Overall very nice place clean excellent staff awesome breakfast and very good coffee bed very comfortable very nice updated rooms.. I plan on staying there again 😀"
Reviewed on Oct 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Sikeston Flight and Hotel Packages
Sikeston flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Need a Car For After Your Flight?
Fullsize
Saint Louis, Missouri, USA
$73
$189 total
found 1 hour ago
Standard
Saint Louis, Missouri, USA
$73
$189 total
found 1 hour ago
Compact
Saint Louis, Missouri, USA
$76
$194 total
found 1 hour ago
Special
Saint Louis, Missouri, USA
$76
$194 total
found 1 hour ago
Frequently asked questions
Plane Tickets To Sikeston
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