Cheap Flights to Sikeston from $34

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

How Much Does it Cost To Fly To Sikeston?

The cheapest prices found with in the last 7 days for return flights were $64 and $34 for one-way flights to Sikeston for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
ATLSt. LouisDecember 4 to December 7$88
TTNSt. LouisOctober 30 to November 3$120
TPASt. LouisJanuary 10 to January 12$150
EWRSt. LouisOctober 31 to October 31$151
LGASt. LouisOctober 28 to October 30$154
SEASt. LouisNovember 5 to November 8$157
LAXSt. LouisNovember 3 to November 7$195
JFKWest PaducahNovember 19 to November 23$372
EWRScott CityNovember 1 to November 3$393
PHLScott CityOctober 30 to October 31$444
LAXWest PaducahDecember 6 to December 13$502
DENScott CityNovember 1 to November 2$532
DFWWest PaducahDecember 27 to December 31$569
TPAScott CityNovember 29 to December 1$737
FCOSt. LouisOctober 31 to November 4$953
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
DENSt. LouisOctober 25 to October 26$130
LGASt. LouisOctober 25 to October 27$154
TTNSt. LouisOctober 24 to October 25$154
LGASt. LouisOctober 25 to October 27$154
ATLSt. LouisOctober 25 to October 29$154
TPASt. LouisOctober 24 to October 31$168
DFWSt. LouisOctober 25 to October 26$226
SEASt. LouisOctober 25 to November 3$331
LAXSt. LouisOctober 25 to October 26$334
DFWScott CityOctober 26 to November 4$412
FCOSt. LouisOctober 25 to November 2$826
*Prices include taxes and fees

Sikeston Flight Information

Traveling to
Sikeston
Lowest Price
$64
Number of Airlines Serving
Airlines Serving
Frontier Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Sikeston Accommodation Deals

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
$75 nightly
The price is $86 total per night from Oct 25 to Oct 26
$86 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,012 reviews)
"The Pear Tree was clean, comfortable, and the staff were extremely friendly!"

Reviewed on Oct 13, 2025

Opens in a new windowPear Tree Inn Sikeston
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
$70 nightly
The price is $79 total per night from Oct 20 to Oct 21
$79 total
Oct 20 - Oct 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,009 reviews)
"The hotel was nice, clean, and had a comfortable mattress."

Reviewed on Oct 11, 2025

Opens in a new windowPear Tree Inn Cape Girardeau West
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
$63 nightly
The price is $72 total per night from Nov 2 to Nov 3
$72 total
Nov 2 - Nov 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,008 reviews)
"The staff was very professional, kind and accommodating."

Reviewed on Oct 12, 2025

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street, Cape Girardeau, MO
$95 nightly
The price is $107 total per night from Oct 26 to Oct 27
$107 total
Oct 26 - Oct 27
Total with taxes and fees
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,004 reviews)
"One of the best hotel stays….. The staff was so friendly. They served warm cookies from 8-9 pm and a very nice breakfast until 10 am. Quiet and safe"

Reviewed on Oct 8, 2025

Opens in a new windowHoliday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Sikeston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
$63 nightly
The price is $72 total per night from Nov 2 to Nov 3
$72 total
Nov 2 - Nov 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,008 reviews)
"The staff was very professional, kind and accommodating."

Reviewed on Oct 12, 2025

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Cape Girardeau
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a water park, and laundry facilities. Popular attractions Riverfront Park and eDen Spa & Salon are ...
9.8/10 Exceptional! (170 reviews)
"Great placeClean amenities bed comfortable location view all excellent Tea room downstairs a nice extra too"

Reviewed on Sep 21, 2025

Opens in a new windowHistorical 'Kage House' Short Term Rental located in "Old Town Cape"
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
$70 nightly
The price is $79 total per night from Oct 23 to Oct 24
$79 total
Oct 23 - Oct 24
Total with taxes and fees
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,008 reviews)
"Room was a bit on the small side, but comfortable."

Reviewed on Oct 13, 2025

Opens in a new windowPear Tree Inn Cape Girardeau Near the Medical Center
Save an average of 15% on thousands of hotels when you're signed in
Quality Inn

Quality Inn

2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
$58 nightly
The price is $65 total per night from Oct 28 to Oct 29
$65 total
Oct 28 - Oct 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7/10 Good! (652 reviews)
"It was so welcoming and peaceful"

Reviewed on Oct 14, 2025

Opens in a new windowQuality Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Sikeston

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
$90 nightly
The price is $103 total per night from Oct 26 to Oct 27
$103 total
Oct 26 - Oct 27
Total with taxes and fees
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,004 reviews)
"The room was just ok. The carpet wasn't vacuumed and my room didn't have any trash bags. There were a lot of crumbs on the floor and the channel guide was dirty. Like a brown sticky sauce or something was on it. The mattress was not the most comfortable and the pillows were lumpy. not fluffy at ..."

Reviewed on Oct 11, 2025

Opens in a new windowDrury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
$75 nightly
The price is $86 total per night from Oct 25 to Oct 26
$86 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,012 reviews)
"The Pear Tree was clean, comfortable, and the staff were extremely friendly!"

Reviewed on Oct 13, 2025

Opens in a new windowPear Tree Inn Sikeston
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
$84 nightly
The price is $96 total per night from Nov 9 to Nov 10
$96 total
Nov 9 - Nov 10
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,008 reviews)
"Clean and roomy room. Friendly and helpful staff. Great breakfast."

Reviewed on Oct 16, 2025

Opens in a new windowBest Western Plus Sikeston
Save an average of 15% on thousands of hotels when you're signed in
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
$90 nightly
The price is $102 total per night from Oct 26 to Oct 27
$102 total
Oct 26 - Oct 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,004 reviews)
Pleasant surprise in Cape Girardeau
"Very clean and comfortable. Good value for the money. Restaurants close by, some within walking distance."

Reviewed on Oct 6, 2025

Opens in a new windowDrury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Sikeston Flight and Hotel Packages

Sikeston flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
The Wildwood Hotel
 White House at Grand Central
Don't see what you're looking for?
See all available trips from Atlanta to Sikeston
View all trips

Need a Car For After Your Flight?

Frequently asked questions

Which airlines fly to Sikeston?
You won't find many airlines that service Sikeston. So, if you're planning to embark on your long-anticipated adventure from here, book a seat with Cape Air as soon as you can.
Where to stay in Sikeston
Lock in your Sikeston accommodations through Travelocity and then turn your attention to what really matters — creating remarkable travel memories. Pick from 12 lodgings from which you can explore this enticing destination.If you're on the hunt for the top accommodation options in Sikeston, we suggest the Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel and the Hampton Inn Sikeston. Reserve a room and then start booking all your exciting getaway activities.
Places to visit in Sikeston
Every visitor will hear talk of The Book Bug at least once. It's a well-known local store. Like some more ideas? Lovers of painting should plan to pay a visit to Sikeston Depot Museum where they'll certainly be impressed. But that's not all there is. Central Park is an urban sanctuary. It is a beautiful place to go for a jog and enjoy the outdoors.
How to get through airport security fast when traveling to Sikeston
Your adventure to Sikeston starts as soon as you've finished all the security checks. Here are some tips and pointers to help you get through quickly:

  • Security personnel will ask to see your travel ID and boarding pass as part of their checks. Tuck them away in a convenient place, so they're all ready for inspection.
  • Remove your shoes and belt before arriving at the airport security checkpoint. Items like these are not permitted to pass through the body scanner.
  • Make sure your phone, laptop and other electronic devices are easily accessible. These items need to be sent through the X-ray machine separately.
  • When you approach the security checkpoint, you'll be asked to place all creams, gels and liquids in a separate tray for scanning. Make sure they're all packed in containers smaller than 3.4 ounces (100 milliliters) and sealed in a clear zip-lock bag.
  • Security personnel will likely tell you to take off your shoes for the body scanner. Choose a pair that you can slip off easily. There's nothing more irritating than having to do your laces up over and over again.
  • Pocketknives and corkscrews are not permitted on board the aircraft. Tuck them away in your checked luggage to avoid them being confiscated at the airport security checkpoint.

Plane Tickets To Sikeston

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Sikeston. Browse through our inventory to explore a wide range of cheap flights to Sikeston to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Sikeston as you anxiously await to exit the plane and explore what Sikeston has to offer. Considering all the amazing local food and culture in Sikeston, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Sikeston to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Sikeston without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Sikeston with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Sikeston today!

Explore More Ways to Travel with Travelocity

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.