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Top Sikeston hotels

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

3 out of 5
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $125 total per night from Jul 23 to Jul 24
$125 total
Jul 23 - Jul 24
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink at the ...
"Always glad to have a smooth check in a little bit of breakfast in the morning. Everything was clean just what you would expect."

Reviewed on Jul 11, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Sikeston
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $120 total per night from Jul 23 to Jul 24
$120 total
Jul 23 - Jul 24
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...
"My 21 year old son stayed at this Hampton Inn on his way back to college in IL. He enjoyed the gym, the indoor pool, the large selection of breakfast items, and the close proximity to I-55. The room was clean and the staff was friendly, even to a 21 year old young man traveling alone. Thank you for ..."

Reviewed on Jul 15, 2026

Opens in a new windowHampton Inn Sikeston
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
Fully refundable
$91 nightly
The price is $104 total per night from Jul 26 to Jul 27
$104 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
"Nice!"

Reviewed on Jul 10, 2026

Opens in a new windowHoliday Inn Express & Suites Sikeston Southwest by IHG
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 out of 5
100 Matthews Lane Sikeston MO
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $71 total per night from Jul 19 to Jul 20
$71 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
"The room itself was not bad. The bathroom floor was cleaned with the wrong product. Walking on it felt like walking on glue. The parking lot and its surroundings are…shady."

Reviewed on Jul 6, 2026

Opens in a new windowTravel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $77 total per night from Aug 9 to Aug 10
$77 total
Aug 9 - Aug 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the ...
"I had a stay at this hotel. The rooms were clean, comfortable, and well maintained. The staff was friendly, professional, and always willing to help. The location was in a convenient place for us to take a quick rest The breakfast was delicious with plenty of options, and the overall atmosphere was ..."

Reviewed on Jul 4, 2026

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2 out of 5
2609 E Malone Ave Sikeston MO
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $72 total per night from Jul 26 to Jul 27
$72 total
Jul 26 - Jul 27
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
"The place smelled funny (cleaning supplies? Furniture was old and dirty Meeger breakfast choices Staff was helpful. Check-in was very good"

Reviewed on Jun 30, 2026

Opens in a new windowSuper 8 by Wyndham Sikeston/Miner Area
Country Yard Inn and Suite

Country Yard Inn and Suite

2 out of 5
110 South Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $63 total per night from Jul 19 to Jul 20
$63 total
Jul 19 - Jul 20
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
"My room had several problems, but I was so tired. I didn’t want to complain about it. Instead, I just made sure I left the property as early as possible in the morning. The problems were as follows. Smoke detector had been pulled out of the wall. I I have no idea if it was operational or not. It ..."

Reviewed on Jul 14, 2026

Opens in a new windowCountry Yard Inn and Suite
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Jul 20 to Jul 21
$128 total
Jul 20 - Jul 21
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Opens in a new windowDrury Inn & Suites Sikeston, MO
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Jul 26 to Jul 27
$103 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...
Opens in a new windowBest Western Plus Sikeston I-55
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Sikeston hotels

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from Jul 26 to Jul 27
$81 total
Jul 26 - Jul 27
Total with taxes and fees
9/10 Wonderful! (1,000 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Sikeston Hotel & Travel Guide\n

Spending several days in Southeast Missouri? With Travelocity, you'll unearth a select number of places to base your adventure in Sikeston. Within 6 miles (10 kilometers) of Sikeston, there are 9 suitable long and short-stay accommodation options.

People watch right by the downtown area of Sikeston. Travelocity-listed rooms here include Days Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest.

If you're heading to the Dexter area in Sikeston, your hotel options include the Hickory House Inn and Dexter Inn. Dexter is 20 miles (34 kilometers) from downtown Sikeston. Another suburb to stay in is Cape Girardeau, 30 miles (50 kilometers) from the center of Sikeston, where you can find the Pear Tree Inn Cape Girardeau West and Holiday Inn Express Hotel & Suites Cape Girardeau I-55.

If you're traveling on a tight budget, you'll be happy to learn that there's a nice selection of mid to low-budget rooms and apartments in Sikeston. Different lower-cost accommodation options are the Super 8 - Sikeston/Miner Area and the Super 8 Cape Girardeau.

The Comfort Inn And Suites is situated 3 miles (5 kilometers) from the heart of Sikeston. If you would prefer another option, the Quality Inn Charleston can be found approximately 13 miles (21 kilometers) away. Some other places to rest your head include the Super 8 Charleston MO and the Pear Tree Inn - Sikeston.

Hayti is 45 miles (73 kilometers) to the south of Sikeston and is where you'll find Hayti Pentecostal Holiness Church and Hayti Park. The Comfort Inn Hayti and Drury Inn & Suites Hayti Caruthersville are just a handful of the comfortable short and long-stay options in Hayti. 60 miles (97 kilometers) to the north of Sikeston, you will find Perryville, which features the Super 8 Perryville and Days Inn Perryville. The National Shrine of Our Lady of the Miraculous Medal and Perryville Country Club are other frequented points of interest to discover in Perryville.

If sport is never far from your mind, put aside some time for a trip to Players Bluegrass Downs, situated 55 miles (87 kilometers) to the east of Sikeston. Book accommodation right by the action at the Holiday Inn Express Hotel & Suites Paducah West or the Residence Inn by Marriott Paducah.

Before you and your traveling partner head out the door to Sikeston, take the time to look through Travelocity's Sikeston city page where you can get the inside scoop on all the attractions to be found here.

Frequently asked questions

What are the top kid-friendly hotels in Sikeston?
Take some of the hassles out of traveling with little ones by staying in a family-friendly hotel in Sikeston. From fun amenities to innovative services, these stays feature perks that'll help make your getaway smooth sailing: You'll be well looked after at Modern and Cozy Apartment with large windows and sunlight.. It comes with pet-friendly facilities, internet access and a knack for making families feel welcome. Otherwise, spend your evenings in Sikeston at Lambert's Homestead. Very Cozy & Clean 5 bed home.. Take advantage of a fireplace, a barbecue grill and more here.
Where can I find cheap hotels in Sikeston?
At Travelocity you'll find really nice hotels in Sikeston at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Sikeston rather than in Sikeston. We may find you even better rates, too.
How do I find the best Sikeston hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Sikeston then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Sikeston?
The cheapest hotel in Sikeston is $63. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Sikeston?
There are 319 hotels in Sikeston on Travelocity.
What are the best hotels in Sikeston?
Sikeston has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Sikeston for you!
When is the best time to visit Sikeston?
If you want the joy of a fun-filled trip in peak season, visit Sikeston during May, June and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Sikeston?
Based on historic data is usually the cheapest month to visit Sikeston. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Sikeston?
There are multiple hotels in Sikeston that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Sikeston. We have plenty of kid-friendly hotels in Sikeston to choose from on Travelocity!
Why book a hotel in Sikeston through Travelocity?
Because we have the top hotels in Sikeston! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Sikeston on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Sikeston hotel reviews by fellow wanderers

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

5 out of 5
Posted 11 hours ago
Travelocity Verified Review
"GOOD"
A verified traveler stayed at Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center

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