Find and compare 3 Star hotels in Sikeston
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Top Sikeston 3 Star hotels
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $113 total per night from Jun 14 to Jun 15
$113 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.6/10 Exceptional! (1,002 reviews)
"Very clean, helpful staff"
Reviewed on Jun 2, 2026
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Jun 10 to Jun 11
$128 total
Jun 10 - Jun 11
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
9.6/10 Exceptional! (1,006 reviews)
"Clean rooms and was ready when we arrived. We did not use the pool but other guests were enjoying it. Breakfast and Kick back were both great meals."
Reviewed on Jun 4, 2026
Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $87 total per night from Jun 21 to Jun 22
$87 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.6/10 Exceptional! (1,011 reviews)
"Lived this hotel offered great evening snacks and drinks and a great continental breakfast."
Reviewed on Jun 4, 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
433 CAPE WEST CROSSINGS Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Jun 14 to Jun 15
$105 total
Jun 14 - Jun 15
Total with taxes and fees
An indoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in ...
9.4/10 Exceptional! (195 reviews)
"The staff were excellent! Front desk and Breakfast staff were very friendly and attentive."
Reviewed on Jun 3, 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $100 total per night from Jun 7 to Jun 8
$100 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
9/10 Wonderful! (777 reviews)
"Beautiful hotel at a very good price."
Reviewed on Jun 5, 2026
Courtyard by Marriott Cape Girardeau Downtown
400 Broadway St. Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $142 total per night from Jul 3 to Jul 4
$142 total
Jul 3 - Jul 4
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.6/10 Exceptional! (514 reviews)
"Beautiful and comfortable room in a vibrant small downtown setting."
Reviewed on May 31, 2026
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Jun 21 to Jun 22
$102 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.4/10 Exceptional! (1,008 reviews)
"The staff at this Drury are always super friendly and helpful. It's nice to have breakfast and an evening meal in the cost of the stay. The rooms are very spacious and the bed is very comfortable. I love the pictures of Cape Girardeau worked into the decorating."
Reviewed on Jun 4, 2026
Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $124 total per night from Jun 14 to Jun 15
$124 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Business travelers can take advantage of the free WiFi in public areas. Guests will appreciate ...
9.4/10 Exceptional! (84 reviews)
"Great stay, kind staff, very clean property."
Reviewed on May 30, 2026
EC Reed's Mercantile and Hotel
301 1st St Marble Hill MO
$95 nightly
The price is $103 total per night from Jun 13 to Jun 14
$103 total
Jun 13 - Jun 14
Total with taxes and fees
The hotel doesn't skimp on freebies - guests receive free continental breakfast and free self parking. If you want to take your pet along, this pet-friendly ...
9.6/10 Exceptional! (95 reviews)
"We didn’t see any staff and everything was out and waiting for us. The property is very well maintained and quaint. There is coffee, water, and snacks for the continental breakfast. The hours of the Mercantile were limited."
Reviewed on May 29, 2026
TownePlace Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $144 total per night from Jun 14 to Jun 15
$144 total
Jun 14 - Jun 15
Total with taxes and fees
An indoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like self-serve breakfast and WiFi in ...
9.2/10 Wonderful! (18 reviews)
"The breakfast staff was not good. The cream needed to be refilled. Oatmeal was not cooked. We had to wait for waffle machine to be fixed."
Reviewed on May 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
3 Star Hotels Sikeston
Maybe you’ve got to travel for work, or perhaps you’re finally ready to book that much-deserved vacation—regardless, it’s time for you to get on a plane and you’re going to make the most of it. You’ve traveled enough to know how important a comfy bed and room service can be, so booking a hotel with all the amenities you need is a priority.
You can find 3 star hotels in Sikeston that keep you close to all the great sightseeing and activities around the area, or even book a place that’s a bit more secluded, if that’s what you prefer. No matter what you’re looking for—whether you’re all about the location or are invested in on-site perks--Travelocity will help you find the accommodation that works best for you.
When it comes to options, you’ll have them. The Sikeston 3 star hotels give you plenty of choices as far as access to the best areas, and many also offer a breakfast buffet, as well as plenty of other amenities like high-speed Wi-Fi and an on-site pool or spa.
Whatever you’re looking for on your next getaway, browse Travelocity’s big selection of hotels to ensure you get the best possible deal. Book one of the best 3 star hotels in Sikeston today!
Recent Sikeston hotel reviews by fellow wanderers
Drury Inn & Suites Sikeston, MO
5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"Clean rooms and was ready when we arrived. We did not use the pool but other guests were enjoying it. Breakfast and Kick back were both great meals."
A verified traveler stayed at Drury Inn & Suites Sikeston, MO
