
Deals on vacations and trips to Sikeston
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Sikeston flight + hotel vacation packages
Price found within the past 48 hours. Click for updated prices.

Country Inn & Suites by Radisson, Fairview Heights, IL
Price was $538, price is now $421 per person
$421
per person
May 21 - May 25
found 13 hours ago
Roundtrip flight included
Orlando (MCO) to St. Louis (STL)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

The Wildwood Hotel
Save 100% on your flight
Price was $754, price is now $463 per person
$463
per person
May 12 - May 16
found 2 hours ago
Roundtrip flight included
Washington (WAS) to St. Louis (STL)
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.

Hilton Garden Inn St. Louis/O'Fallon MO
Save 100% on your flight
Price was $1,030, price is now $782 per person
$782
per person
May 12 - May 16
found 2 hours ago
Roundtrip flight included
Washington (WAS) to St. Louis (STL)
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free self parking and free WiFi. A business center, a grocery/convenience store, and a lobby fireplace are also on offer.

The Cheshire
Save 100% on your flight
Price was $1,097, price is now $835 per person
$835
per person
May 14 - May 19
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free English breakfast each morning.

Ameristar Casino Resort and Spa
Price was $807, price is now $630 per person
$630
per person
Jun 15 - Jun 19
found 1 day ago
Roundtrip non-stop flight included
Orlando (MCO) to St. Louis (STL)
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside bar.
Top Sikeston hotels deals

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$94 nightly
The price is $108 total per night
$108 total
Apr 9 - Apr 10
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$93 nightly
The price is $106 total per night
$106 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. A 24-hour business center, a snack bar/deli, and express check-out are also on offer.
Pool
Breakfast included

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$79 nightly
The price is $90 total per night
$90 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour business center, a grocery/convenience store, and express check-out are also on offer.
Pool
Breakfast included

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$65 nightly
The price is $75 total per night
$75 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.
Breakfast included
Pet friendly

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$64 nightly
The price is $73 total per night
$73 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 3 onsite conference rooms. Enjoy the gym and conveniences like a 24-hour front desk and laundry facilities.
Breakfast included
Pet friendly

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Free Cancellation
$93 nightly
The price is $105 total per night
$105 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Sikeston Depot Museum
You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this relaxing area, you can savor the top-notch restaurants.
Central Park
Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this relaxing area, you can savor the top-notch restaurants.
City of Miner Convention Center
Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this family-friendly area, you can savor the top-notch restaurants.
Frequently asked questions
Where to stay in Sikeston: Best areas for travelers
- Miner: If you're in the mood for some sightseeing in this neighborhood, head straight for The Book Bug. It's just one reason many visitors stay here. We suggest checking out the rates and reviews of the Drury Inn & Suites Sikeston, MO, the Motel 6 Sikeston MO and the Pear Tree Inn Sikeston.
- Charleston: This is a great neighborhood for your next getaway — not the busiest place around, but still highly rated by many travelers. For an enjoyable stay, make a reservation at the Quality Inn Charleston I-57 or the Super 8 by Wyndham Charleston MO.
Photos of local treasures
Browse Sikeston vacation photos for more inspiration




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