Cape Girardeau Vacation Packages 2025/2026 from $721

Cape Girardeau flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Super 8 by Wyndham Carbondale

per person

Sep 9 - Sep 16

found 6 hours ago

Roundtrip non-stop flight included

Mosinee (CWA) to Cape Girardeau (CGI)

This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Multilingual staff at the 24-hour front desk can provide around-the-clock assistance.

Hampton Inn Carbondale

per person

Sep 9 - Sep 16

found 6 hours ago

Roundtrip non-stop flight included

Mosinee (CWA) to Cape Girardeau (CGI)

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like buffet breakfast and free self parking.

Makanda Inn

per person

Sep 9 - Sep 16

found 6 hours ago

Roundtrip non-stop flight included

Mosinee (CWA) to Cape Girardeau (CGI)

A restaurant and a bar/lounge are featured at this bed & breakfast. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee shop, a terrace, and a lobby fireplace are also on offer.

Holiday Inn Carbondale-Conference Center by IHG

per person

Sep 9 - Sep 16

found 6 hours ago

Roundtrip non-stop flight included

Mosinee (CWA) to Cape Girardeau (CGI)

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free self parking, a terrace, and express check-out are also offered.

Home2 Suites by Hilton Carbondale

per person

Sep 9 - Sep 16

found 6 hours ago

Roundtrip non-stop flight included

Mosinee (CWA) to Cape Girardeau (CGI)

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Top Cape Girardeau hotels deals

The Riverview

777 Main St, Cape Girardeau, MO

Free Cancellation

Reserve now, pay when you stay

$117 nightly

$132 total

Jul 9 - Jul 10

Total includes taxes and fees

This hotel features a casino and 2 restaurants. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like free self parking and WiFi in public areas. A coffee shop is provided and the front desk is staffed around-the-clock.

Parking included

Free WiFi

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive, Cape Girardeau, MO

Free Cancellation

Reserve now, pay when you stay

$90 nightly

$102 total

Jul 13 - Jul 14

Total includes taxes and fees

This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr, Cape Girardeau, MO

Free Cancellation

Reserve now, pay when you stay

$101 nightly

$115 total

Jul 14 - Jul 15

Total includes taxes and fees

This hotel features an indoor pool and a gym. Guests will appreciate freebies like daily breakfast and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.

Pool

Breakfast included

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street, Cape Girardeau, MO

Free Cancellation

$99 nightly

$112 total

Aug 1 - Aug 2

Total includes taxes and fees

A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.

Pool

Breakfast included

Pear Tree Inn Cape Girardeau Near the Medical Center

3248 William St, Cape Girardeau, MO

Free Cancellation

Reserve now, pay when you stay

$67 nightly

$76 total

Jul 13 - Jul 14

Total includes taxes and fees

Free WiFi in public areas and express check-out are available at this hotel. Staff at the 24-hour front desk can provide around-the-clock assistance.

Pet friendly

Free WiFi

Hampton Inn Cape Girardeau I 55 East

207 S Mt Auburn Rd, Cape Girardeau, MO

Free Cancellation

Reserve now, pay when you stay

$110 nightly

$124 total

Jul 20 - Jul 21

Total includes taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Southeast Missouri State University

4.5/5(76 reviews)

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Isle Casino Cape Girardeau

4.5/5(48 reviews)

Why not roll the dice with a visit to Isle Casino Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.

Riverfront Bridge Park

4.5/5(43 reviews)

Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.

Frequently asked questions

How much are vacation packages to Cape Girardeau?

$721 is all you need to spend for a wonderful escape in Cape Girardeau. Bundle your flights and hotel into a Travelocity vacation package and watch how the savings start to add up. With prices this good, there's never been a better time to travel.

How long should my Cape Girardeau vacation be?

Many visitors like to stay roughly 2 nights in Cape Girardeau. But what works for them mightn't work for you. Whether you opt to stay for a couple of days or a couple of weeks, you'll love exploring all the amazing things that this place has to offer.

Where can I get the best vacation package deals for Cape Girardeau?

Travelocity is where to go to score a sensational Cape Girardeau package deal. Choose from 400 partner airlines and 1,000,000 hotels worldwide and create a vacation package that's perfect for you. With so many options, now's the time to book your next big adventure.

Why should I book my Cape Girardeau vacation bundle via Travelocity?

With exceptional service, 24/7 support and some of the most gorgeous getaways on offer, you'll never roam alone. And if you happen to find a better price, we'll match it. That's our Price Match Guarantee.

Can I save money on my Cape Girardeau car rental if I combine it with my hotel or flight?

With a Cape Girardeau vacation package, you can bundle your flight, hotel and car bookings and save tons. If you're eager to uncover the best of this impressive region, why not start with Busch Stadium? This must-see attraction is 100 mi from Cape Girardeau. With your own set of wheels, you'll be there in a jiffy.

Which airport is best for Cape Girardeau?

It's very likely you'll be arriving at Williamson County Regional Airport (MWA), situated 40 mi northeast of downtown Cape Girardeau. Cape Girardeau Municipal Airport (CGI) (6 mi away from central Cape Girardeau) and Barkley Regional Airport (PAH) (45 mi away from central Cape Girardeau) are other choices.

What is there to do in Cape Girardeau?

While venturing off the beaten track can be rewarding, you shouldn't ignore the big sights that make a destination famous. Isle Casino Cape Girardeau and Cape Splash Family Aquatic Center are a couple of them in Cape Girardeau.

Where should I stay when visiting Cape Girardeau?

Many visitors opt to check in to the Drury Plaza Hotel Cape Girardeau Conference Center. It's a terrific base for your Cape Girardeau getaway.