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Top Cape Girardeau 3 Star hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $113 total per night from May 3 to May 4
$113 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.6/10 Exceptional! (1,012 reviews)
This is my home away from home place! You get free dinner and the BEST breakfast buffet ever with your stay! Plus the indoor pool and hot tub! There is a thermostat in every room to control requirement. It’s just simply the best hotel ever seriously I absolutely love staying here!!!

Reviewed on Apr 18, 2026

Opens in a new windowDrury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $107 total per night from May 10 to May 11
$107 total
May 10 - May 11
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.4/10 Exceptional! (1,005 reviews)
Everything was fine.

Reviewed on Apr 19, 2026

Opens in a new windowDrury Inn & Suites Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $96 total per night from Apr 27 to Apr 28
$96 total
Apr 27 - Apr 28
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
9/10 Wonderful! (751 reviews)
Had to wait 40 minutes in line to check-in, only one person working. That person was very nice for being as busy as she was. The room was larger than most hotel rooms and seemed clean. At the complementary breakfast there was only one urn of coffee, and it was completely empty. 😢

Reviewed on Apr 19, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3 out of 5
225 Drury Lane Jackson MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $85 total per night from May 17 to May 18
$85 total
May 17 - May 18
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
9.6/10 Exceptional! (1,003 reviews)
This is a lovely hotel! Homey and comfortable yet clean and updated. The staff is so kind and welcoming. I will 100% choose this hotel on my next to the area.

Reviewed on Apr 15, 2026

Opens in a new windowDrury Inn & Suites Jackson MO
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St. Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $142 total per night from May 17 to May 18
$142 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9.6/10 Exceptional! (502 reviews)
The staff was very helpful and friendly. The hotel and the rooms were very clean and smelled so good. Would stay here again

Reviewed on Apr 7, 2026

Opens in a new windowCourtyard by Marriott Cape Girardeau Downtown
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

3 out of 5
433 CAPE WEST CROSSINGS Cape Girardeau MO
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $95 total per night from Apr 30 to May 1
$95 total
Apr 30 - May 1
Total with taxes and fees
An indoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi in ...
9.4/10 Exceptional! (176 reviews)
The woman at breakfast was amazing. So helpful and smiling. It was a great stay, only complaint was there were a lot of rowdy kids running around the halls. It doesn’t bother me during decent hours but after 9pm and before 8am people should be able to rest.

Reviewed on Apr 19, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Cape Girardeau
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

3 out of 5
301 1st St Marble Hill MO
$83 nightly
The price is $91 total per night from May 19 to May 20
$91 total
May 19 - May 20
Total with taxes and fees
The hotel doesn't skimp on freebies - guests receive free continental breakfast and free self parking. If you want to take your pet along, this pet-friendly ...
9.6/10 Exceptional! (85 reviews)
Parking was easy. The staff were super friendly and helpful. Room was nice and comfortable. I definetely recommend staying here if you are in this area.

Reviewed on Mar 22, 2026

Opens in a new windowEC Reed's Mercantile and Hotel
Makanda Inn

Makanda Inn

3.5 out of 5
855 Old Lower Cobden Road Makanda IL
$255 nightly
The price is $282 total per night from Apr 26 to Apr 27
$282 total
Apr 26 - Apr 27
Total with taxes and fees
A restaurant and a bar/lounge are featured at this bed & breakfast. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...
10/10 Exceptional! (36 reviews)
Friendly staff that met our needs.

Reviewed on Apr 3, 2026

Opens in a new windowMakanda Inn
Cozy Anna Home Near Southern Illinois Attractions!

Cozy Anna Home Near Southern Illinois Attractions!

3 out of 5
Anna IL
Free WiFi in public areas is available at this cottage. Take advantage of the free self parking.
10/10 Exceptional! (1 review)
Good communication with the owners. Nice perks such as coffee, tea, and hygiene items.

Reviewed on Feb 3, 2025

Opens in a new windowCozy Anna Home Near Southern Illinois Attractions!
Oak Grove Cabins

Oak Grove Cabins

3 out of 5
413 Oak Grove Rd Makanda IL
A hot tub is featured at this cabin, along with barbecue grills. Take advantage of the free self parking.
10/10 Exceptional! (5 reviews)
Awsome cabin and really private. Lots of nice touches. Great coverage for our Verizon hotspot.

Reviewed on Feb 21, 2019

Opens in a new windowOak Grove Cabins
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

3 Star Hotels Cape Girardeau

Maybe you’ve got to travel for work, or perhaps you’re finally ready to book that much-deserved vacation—regardless, it’s time for you to get on a plane and you’re going to make the most of it. You’ve traveled enough to know how important a comfy bed and room service can be, so booking a hotel with all the amenities you need is a priority.

You can find 3 star hotels in Cape Girardeau that keep you close to all the great sightseeing and activities around the area, or even book a place that’s a bit more secluded, if that’s what you prefer. No matter what you’re looking for—whether you’re all about the location or are invested in on-site perks--Travelocity will help you find the accommodation that works best for you.

When it comes to options, you’ll have them. The Cape Girardeau 3 star hotels give you plenty of choices as far as access to the best areas, and many also offer a breakfast buffet, as well as plenty of other amenities like high-speed Wi-Fi and an on-site pool or spa.

Whatever you’re looking for on your next getaway, browse Travelocity’s big selection of hotels to ensure you get the best possible deal. Book one of the best 3 star hotels in Cape Girardeau today!

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