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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Enjoy free breakfast at this spa Cape Girardeau hotel

Choose dates to view prices

Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Relax in the stylish lobby, featuring a fireplace, comfortable seating, and a large flat-screen TV.
Indulge in a diverse selection of international cuisine at our hotel's buffet.
Relax in this stylish room with a comfortable seating area, wooden staircase, and modern decor.
Comfortable room with a large bed, desk, and television, offering a peaceful retreat.
Relax by the pool surrounded by comfortable lounge chairs and tables.

Popular amenities

  • Laundry
  • Housekeeping

Explore the area

Map
3253 William Street, Cape Girardeau, MO, 63701
  • Saint Francis Medical Center
    ‪6 min walk‬
  • Southeast Missouri State University
    ‪6 min drive‬
  • Isle Casino Cape Girardeau
    ‪8 min drive‬
  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪7 min drive‬

Room options

View all photos for Suite, 1 King Bed

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 1 King Bed

9.6 out of 10
Exceptional
(29 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 1 Queen Bed

1 bedroom, premium bedding, down comforters, pillowtop beds

Standard Room, 1 Queen Bed

9.2 out of 10
Wonderful
(5 reviews)
  • 400 sq ft
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 2 Queen Beds, Accessible (Mobility)

9.6 out of 10
Exceptional
(13 reviews)
  • 400 sq ft
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(50 reviews)
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.6 out of 10
Exceptional
(5 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room

1 bedroom, premium bedding, down comforters, pillowtop beds

Standard Room

8.4 out of 10
Very good
(5 reviews)
  • 400 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower) | 1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(5 reviews)
  • 400 sq ft
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Mobility)

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 Bedroom (Feature)

1 bedroom, premium bedding, down comforters, pillowtop beds

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 2
  • 1 Queen Bed

About the neighborhood

Cape Girardeau

Near the airport.A stay at this hotel places you within half a mile (1 km) of Saint Francis Medical Center and 3 miles (5 km) of Saint Francis Healthcare System. Southeast Missouri Hospital and Cape Splash Family Aquatic Center are also within 3 miles (5 km).

What's nearby

  • Saint Francis Medical Center - 6 min walk - 0.4 miles
  • Southeast Missouri Hospital - 5 min drive - 3.3 miles
  • Southeast Missouri State University - 6 min drive - 3.5 miles
  • Riverfront Bridge Park - 7 min drive - 4.0 miles
  • Isle Casino Cape Girardeau - 8 min drive - 4.3 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬6 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪Panera Bread - ‬2 min walk
  • ‪Texas Roadhouse - ‬5 min walk
  • ‪O'Charley's Restaurant + Bar - ‬4 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Enjoy free breakfast at this spa Cape Girardeau hotel
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers its guests a full-service spa, an indoor pool, and a fitness center. Public spaces have free WiFi and wired Internet. A business center and a meeting room are available. Free breakfast is served. Event space at this hotel measures 118 square feet (11 square meters) and includes conference space. The business-friendly Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG also features a vending machine, complimentary newspapers in the lobby, and laundry facilities. Self parking is free.

This Cape Girardeau hotel is smoke free.

  • 1 building
  • 102 guestrooms or units
  • 4 levels
  • 118 sq ft of conference space
  • 11 sq m of conference space
  • Breakfast available (free)
  • Poolside lounge chairs
  • Business facilities
  • Conference space
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Storage area for luggage
  • Front-desk safe
  • Newspapers in lobby (free)
  • Bellhop
  • No smoking on site
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers 102 accommodations with safes and coffee/tea makers. Accommodations offer separate sitting areas. Pillowtop beds feature down comforters and premium bedding. A pillow menu is available. 52-inch flat-screen televisions come with premium cable channels. Bathrooms include complimentary toiletries and hair dryers.

Guests can surf the web using the complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Housekeeping is provided daily.

Guests can indulge in a pampering treatment at the hotel's full-service spa.

Languages

English

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  • Breakfast included
  • Pet friendly
4.8 out of 5, Exceptional, 1,011 reviews
$90 nightly
The price is $102
Jul 31 - Aug 1
Total includes taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center

Property amenities

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator

Room amenities

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • No pets allowed

Children and extra beds

  • Children are welcome.
  • Cribs (infant beds) are not available.

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, and Carte Blanche. Cash is not accepted. For guests' safety, the property includes a smoke detector in each accommodation. Cashless payment methods are available for all transactions. This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

We should mention

  • Pool access available from 8 AM to 11 PM.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

How close is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG to the airport?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is 6.1 mi (10-min drive) away from the Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport, the closest popular airport to the property.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of Jul 24, 2025, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on Aug 22, 2025 start from $97.0, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have an airport shuttle?

Airport shuttle services are not available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offer free breakfast?

Yes, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers free breakfast.

Is there a casino at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, there is no casino at this hotel, but Isle Casino Cape Girardeau (7-min drive) is nearby.

What time is check-in at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

Is there free parking at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

This hotel offers free self parking.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG features an indoor pool. Guests can enjoy pool access from 8 AM to 11 PM.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a spa?

Yes, this hotel has a spa.

How close is Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG to downtown Cape Girardeau?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is 3.2 mi away from Cape Girardeau.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 790 out of 1006 reviews
Rating 8 - Good. 152 out of 1006 reviews
Rating 6 - Okay. 34 out of 1006 reviews
Rating 4 - Poor. 13 out of 1006 reviews
Rating 2 - Terrible. 17 out of 1006 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

Reviews

10/10 Excellent

david

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent
Stayed 1 night in May 2025

10/10 Excellent

Julia

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Great location. Walmart close. Some rooms’ windows are facing the pool and this loud until 10pm if the pool is occupied. If you have anyone who goes to bed early stay away from those. Room are huge!!
Stayed 3 nights in May 2025

10/10 Excellent

Xenia

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Return Stay💋

I chose this hotel because I stayed 8 months ago when I daughter was scheduled for a C-section and I was so happy with the staff, location of the property and condition of the room I had to return.
Stayed 1 night in Apr 2025

10/10 Excellent

Nick

Traveled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Front desk was super helpful at check in and very courteous throughout the whole stay
Stayed 2 nights in Apr 2025

10/10 Excellent

Lindsey

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Check-in was seamless. Staff was kind. They had fresh cookies at 8 p.m. which the kids loved. The pool area is very well maintained and nice. Fitness area looked very nice right through the pool area. Rooms are clean, decent and in good repair, and the hotel is quiet. Could not be happier with the value of this stay for my family. We have Panera, Starbucks, Chik-fil-a, Texas Roadhouse, Cracker Barrel and more right around our hotel. There is a shopping center nearby with a TJmaxx and some other stores. Overall a really great stop that we will remember when we take this route for future drives. Thank you, Holiday Inn Express!
Stayed 1 night in Apr 2025

10/10 Excellent

Theresa, Battle Creek

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Apr 2025

2/10 Terrible

William

Traveled with family
Liked: Room comfort
Disliked: Staff & service, property conditions & facilities

Bad place to stay

It was not a very good place for the money you pay the floor was squeaky upstairs so i heard that most of the night and also sounded like a heard of cattle running across the floor
Stayed 1 night in Apr 2025

10/10 Excellent

Verified traveler

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Super Cute

This hotel was super cute and the staff was quite friendly. Our room had a window overlooking the pool so that was pretty neat. Breakfast was also nice.
Stayed 1 night in Apr 2025

10/10 Excellent

Constance, Washington

Liked: Cleanliness, staff & service, property conditions & facilities
Will definitely stay there again!!
Stayed 1 night in Apr 2025

10/10 Excellent

Joan

Liked: Cleanliness, amenities
Excellent Hotel. Good breakfast. Great room. We will stay again if we are in the area
Stayed 1 night in Mar 2025

10/10 Excellent

rick

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Mar 2025

10/10 Excellent

Sarah

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Apr 2025

8/10 Good

Michael

Stayed 1 night in Apr 2025

10/10 Excellent

Scott

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Apr 2025

10/10 Excellent

Brian

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We enjoyed our stay both times on our vacation to New Orleans.
Stayed 1 night in Mar 2025

8/10 Good

Ashley

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location. Clean
Stayed 2 nights in Mar 2025

10/10 Excellent

Tamara

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

10/10 Excellent

Thea

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was a nice hotel to spend the night on a long road trip. We did not use the pool as it was completely full of kids who did not see to be supervised well by their parents, which is not the hotel's fault.
Stayed 1 night in Mar 2025

10/10 Excellent

meagan

Stayed 1 night in Mar 2025

10/10 Excellent

Robin

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel was clan and the staff was friendly. The workout room and the pool were small but clean. The staff were friendly.
Stayed 3 nights in Mar 2025

10/10 Excellent

Shannon

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

I'll be back!!

Needed an overnight traveling back home. Nabbed this great room. Just wish that I would have been there a bit lo ger to enjoy it. Super hot shower with great water pressure was also very welcome. The macadamia nut cookies were awesome!!
Stayed 1 night in Mar 2025

10/10 Excellent

Kyle

Traveled with family and small children, Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean, great location especially while traveling (gas stations/stores/restaurants) parking was also very convenient. The breakfast in the morning was free with many options. Dining area was also clean and I saw staff cleaning just about everywhere on every surface on our way to check out. Would stay again.
Stayed 1 night in Mar 2025

10/10 Excellent

Ted

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
it was very clean, comfortable, Rooma are super cool for the price. Just a great experience.
Stayed 2 nights in Mar 2025

8/10 Good

steve

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Dec 2024

10/10 Excellent

Alicia

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025