Explore 7 Luxury Hotels in Sikeston
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Best Luxury Hotels in Sikeston
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
"Very nice hospitality and accommodations ComfortableGreat location"
Reviewed on Jul 5, 2026
Drury Inn & Suites Sikeston, MO
"Our room looked new and clean and specious ! Breakfast was delicious, variety and better quality compared to some other.. The air conditioner was quite as well.The environments were safe. Overall we loved our stay, thank you for your great service !"
Reviewed on Jul 31, 2026
Quality Inn Cape Girardeau North
"The room smelled like mildew and had my clothes and food smelling like it too. 0/10 would not recommend."
Reviewed on Jul 30, 2026
Days Inn and Suites by Wyndham Sikeston
Drury Inn & Suites Cape Girardeau
Sikeston Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Sikeston luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Sikeston to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Sikeston will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Sikeston, and plan your next opulent escape.
Sikeston hotels essential information
Accommodation | 318 hotels |
|---|---|
Lowest Price | $76 |
Highest Price | $128 |
Popular hotels | Days Inn and Suites by Wyndham Sikeston, Historical 'Kage House' Short Term Rental located in "Old Town Cape" , Quality Inn Cape Girardeau North, Drury Inn & Suites Sikeston, MO, Drury Inn & Suites Cape Girardeau |
Popular Luxury Stays in Sikeston
Recent Sikeston Hotel Reviews By Fellow Wanderers
Drury Inn & Suites Sikeston, MO
"Our room looked new and clean and specious ! Breakfast was delicious, variety and better quality compared to some other.. The air conditioner was quite as well.The environments were safe. Overall we loved our stay, thank you for your great service !"