Explore 7 Luxury Hotels in Sikeston
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Best Luxury Hotels in Sikeston
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
"Very nice hospitality and accommodations ComfortableGreat location"
Reviewed on Jul 5, 2026
Drury Inn & Suites Sikeston, MO
"I love this hotel it is my go to weekend getaway. So clean so comfortable always great food and the bartender is friendly and funny I have followed her from the pear tree next door. Their pool is good for rain or shine"
Reviewed on Sep 15, 2026
Days Inn and Suites by Wyndham Sikeston
"The room did not have an extra roll of toilet paper and also the hairdryer did not work. That was the only two things that was not. I was not happy with."
Reviewed on Sep 13, 2026
Quality Inn Cape Girardeau North
Drury Inn & Suites Cape Girardeau
Sikeston Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Sikeston luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Sikeston to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Sikeston will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Sikeston, and plan your next opulent escape.
Sikeston hotels essential information
Accommodation | 318 hotels |
|---|---|
Lowest Price | $67 |
Highest Price | $128 |
Popular hotels | Days Inn and Suites by Wyndham Sikeston, Historical 'Kage House' Short Term Rental located in "Old Town Cape" , Quality Inn Cape Girardeau North, Drury Inn & Suites Sikeston, MO, Drury Inn & Suites Cape Girardeau |
Popular Luxury Stays in Sikeston
Recent Sikeston Hotel Reviews By Fellow Wanderers
Drury Inn & Suites Sikeston, MO
"I love this hotel it is my go to weekend getaway. So clean so comfortable always great food and the bartender is friendly and funny I have followed her from the pear tree next door. Their pool is good for rain or shine"
Days Inn and Suites by Wyndham Sikeston
"The room did not have an extra roll of toilet paper and also the hairdryer did not work. That was the only two things that was not. I was not happy with."