Book Hotels in Charleston, MO

Top Charleston hotels

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive Cape Girardeau MO

Fully refundableReserve now, pay when you stay

$100 nightly

$113 total

Aug 16 - Aug 17

Total with taxes and fees

This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

"Everything about this property is 1000000/100000"

Reviewed on Aug 9, 2026

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

Fully refundable

$105 nightly

$118 total

Sep 3 - Sep 4

Total with taxes and fees

A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public ...

"Very nice hotel and staff. Would definitely recommend"

Reviewed on Aug 9, 2026

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

Fully refundable

$83 nightly

$99 total

Aug 30 - Aug 31

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking, ...

"Our stove had a short in it so I wasn’t able to cook"

Reviewed on Aug 10, 2026

The Riverstone Hotel Charleston-Sikeston

102 Drake St Charleston MO

Fully refundable

$66 nightly

$74 total

Sep 7 - Sep 8

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 24-hour ...

"The ad and picture for the hotel is a little deceiving. It shows a large fountain in front of the front lobby. There was none. This is the former Quality Inn Hotel was not good at all. The hotel has been cleaned up and rebranded. The room was nice. My only concern was all the bugs that were outside ..."

Reviewed on Aug 10, 2026

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

Fully refundableReserve now, pay when you stay

$56 nightly

$62 total

Sep 8 - Sep 9

Total with taxes and fees

This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. There's a computer ...

"Nice staff. Very accommodating."

Reviewed on Aug 9, 2026

Eagle Inn Charleston

2811 East Marshall Street Charleston MO

Fully refundableReserve now, pay when you stay

$69 nightly

$77 total

Aug 12 - Aug 13

Total with taxes and fees

A gym is featured at this motel, along with free self parking. WiFi in public areas is free. Staff at the 24-hour front desk can provide around-the-clock ...

"Great"

Reviewed on Apr 14, 2026

The Riverview

777 Main St Cape Girardeau MO

Fully refundableReserve now, pay when you stay

$109 nightly

$123 total

Aug 12 - Aug 13

Total with taxes and fees

This hotel features a casino and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. ...

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO

Fully refundableReserve now, pay when you stay

$111 nightly

$128 total

Aug 15 - Aug 16

Total with taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

Fully refundableReserve now, pay when you stay

$72 nightly

$81 total

Aug 16 - Aug 17

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Charleston hotels

Eagle Inn Charleston

2811 East Marshall Street Charleston MO

$69 nightly

$77 total

Aug 12 - Aug 13

Total with taxes and fees

6.6/10 (106 reviews)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Charleston with star-rating

Check Charleston Hotels by Star Rating

Charleston Hotel & Travel Guide\n

Researching your trip to Sikeston? To experience it like the locals do, research places to put up your feet which are within a short drive from the hustle and bustle of Charleston. Charleston lists 3 modern hotels and apartments within a 6-mile (10-kilometer) distance.

Wander the streets right by the center of Charleston. Hotels located here include Quality Inn Charleston and Super 8 Charleston MO.

11 miles (18 kilometers) outside of the town center of Charleston, you will find the Comfort Inn And Suites. The Americas Best Value Inn & Suites Sikeston is located about 11 miles (18 kilometers) away. Some more alternatives in the neighborhood are the Super 8 - Sikeston/Miner Area as well as the Days Inn Sikeston.

The nearest places to spend the night in Sikeston are Cape Girardeau and Dexter. Cape Girardeau is 30 miles (51 kilometers) to the northwest of Charleston, while Dexter is 35 miles (57 kilometers) to the northwest. Hotels and apartments in Cape Girardeau include the Pear Tree Inn Cape Girardeau West and Holiday Inn Express Hotel & Suites Cape Girardeau I-55. The Oak Tree Inn Dexter and Hickory House Inn are a selection of the lodgings in Dexter.

If watching sport is never far from your mind, be sure to visit Rent One Park, which can be found 60 miles (98 kilometers) to the north of Charleston. Find a Travelocity-listed hotel surrounded by the sporting action at the Fairfield Inn and Suites by Marriott Marion or the Holiday Inn Express Hotel & Suites Marion Northeast.

Travelocity's comprehensive travel guide is a good way to uncover more secrets of Charleston.

Frequently asked questions

What are the top kid-friendly hotels in Charleston?

Take some of the worries out of traveling with kids by staying in a family-friendly Charleston hotel. From special amenities to more services, these properties come with perks that'll help make your getaway smooth sailing: Quality Inn Charleston I-57 will help make your trip the most memorable one yet. It comes with lots of conveniences aimed at families, such as a swimming pool and complimentary breakfast. Also check out Super 8 by Wyndham Charleston MO. It comes with complimentary breakfast, pet-friendly facilities and lots of opportunities to spend time as a family.

Where can I find cheap hotels in Charleston?

At Travelocity you'll find really nice hotels in Charleston at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Charleston rather than in Charleston. We may find you even better rates, too.

How do I find the best Charleston hotel deals?

Simple! On Travelocity, look through the fantastic offers we've already found in Charleston then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.

How much does it cost to stay in a hotel in Charleston?

The cheapest hotel in Charleston is $62. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.

How many hotels are in Charleston?

There are 104 hotels in Charleston on Travelocity.

What are the best hotels in Charleston?

Charleston has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Charleston for you!

When is the best time to visit Charleston?

If you want the joy of a fun-filled trip in peak season, visit Charleston during March, April and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, February and October.

When is the cheapest time to stay in Charleston?

Based on historic data is usually the cheapest month to visit Charleston. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.

Are there any great family-friendly hotels in Charleston?

There are multiple hotels in Charleston that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Charleston. We have plenty of kid-friendly hotels in Charleston to choose from on Travelocity!

Why book a hotel in Charleston through Travelocity?

Because we have the top hotels in Charleston! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!

How do I cancel my hotel booking in Charleston on Travelocity?

Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Charleston hotel reviews by fellow wanderers

The Riverstone Hotel Charleston-Sikeston

4 out of 5

Posted 17 hours ago

Travelocity Verified Review

"The ad and picture for the hotel is a little deceiving. It shows a large fountain in front of the front lobby. There was none. This is the former Quality Inn Hotel was not good at all. The hotel has been cleaned up and rebranded. The room was nice. My only concern was all the bugs that were outside the room door and flew into the room when you opened your door at night. The other thing that I did not like was the surprise $100 fee that I had to pay up front for potential damage to the room. This fee was returned during check out."

A verified traveler stayed at The Riverstone Hotel Charleston-Sikeston