Book Hotels in Charleston, MO

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Top Charleston hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Oct 5 to Oct 6
$102 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"This is a beautiful, up-to-date facility. The room was spacious with very comfortable beds. Our favorite part of our stay was the food and drinks provided. We took advantage of the free snacks and drinks on the main level in the evening. They also provide dinner, but we chose to eat at the onsite ..."

Reviewed on Sep 26, 2025

Opens in a new windowDrury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $103 total per night from Oct 5 to Oct 6
$103 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Everything was extremely nice"

Reviewed on Sep 22, 2025

Opens in a new windowDrury Inn & Suites Sikeston, MO
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3 out of 5
400 Broadway St., Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $142 total per night from Oct 19 to Oct 20
$142 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Very nice hotel within walking distance to many good restaurants"

Reviewed on Sep 28, 2025

Opens in a new windowCourtyard by Marriott Cape Girardeau Downtown
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $149 total per night from Oct 12 to Oct 13
$149 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a casino and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference space. ...
"Staff friendly, room is clean and quiet"

Reviewed on Sep 25, 2025

Opens in a new windowThe Riverview
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Oct 2 to Oct 3
$79 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Everything was clean and looked newly renovated. Staff was friendly. Parking was convenient and the area seemed safe."

Reviewed on Sep 26, 2025

Opens in a new windowPear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Oct 5 to Oct 6
$79 total
Oct 5 - Oct 6
Total with taxes and fees
Free WiFi in public areas and express check-out are available at this hotel. Staff at the 24-hour front desk can provide around-the-clock assistance.
"Staff was friendly, room was clean, good location, good rate."

Reviewed on Sep 22, 2025

Opens in a new windowPear Tree Inn Cape Girardeau Near the Medical Center
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 out of 5
102 Drake St, I-57 Exit 10, Charleston, MO
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $73 total per night from Oct 6 to Oct 7
$73 total
Oct 6 - Oct 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the business ...
"This property was clean but need more maintenance outside and need updating"

Reviewed on Sep 24, 2025

Opens in a new windowQuality Inn Charleston - Sikeston
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St, Charleston, MO
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $62 total per night from Oct 2 to Oct 3
$62 total
Oct 2 - Oct 3
Total with taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. There's a computer ...
"Thank you!!!"

Reviewed on Sep 26, 2025

Opens in a new windowSuper 8 by Wyndham Charleston/Sikeston East MO
Eagle Inn Charleston

Eagle Inn Charleston

2 out of 5
2811 East Marshall Street, Charleston, MO
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Oct 1 to Oct 2
$71 total
Oct 1 - Oct 2
Total with taxes and fees
A gym is featured at this motel, along with free self parking. WiFi in public areas is free. Staff at the 24-hour front desk can provide around-the-clock ...
"Furniture missing knobs. No chair!!??? No coffee!!?? No breakfast. Nice location. Nice staff!!"

Reviewed on May 21, 2025

Opens in a new windowEagle Inn Charleston
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Charleston hotels

Eagle Inn Charleston

Eagle Inn Charleston

2811 East Marshall Street, Charleston, MO
$64 nightly
The price is $71 total per night from Oct 1 to Oct 2
$71 total
Oct 1 - Oct 2
Total with taxes and fees
6.6/10 (101 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Charleston Hotel & Travel Guide\n

Researching your trip to Sikeston? To experience it like the locals do, research places to put up your feet which are within a short drive from the hustle and bustle of Charleston. Charleston lists 3 modern hotels and apartments within a 6-mile (10-kilometer) distance.

Wander the streets right by the center of Charleston. Hotels located here include Quality Inn Charleston and Super 8 Charleston MO.

11 miles (18 kilometers) outside of the town center of Charleston, you will find the Comfort Inn And Suites. The Americas Best Value Inn & Suites Sikeston is located about 11 miles (18 kilometers) away. Some more alternatives in the neighborhood are the Super 8 - Sikeston/Miner Area as well as the Days Inn Sikeston.

The nearest places to spend the night in Sikeston are Cape Girardeau and Dexter. Cape Girardeau is 30 miles (51 kilometers) to the northwest of Charleston, while Dexter is 35 miles (57 kilometers) to the northwest. Hotels and apartments in Cape Girardeau include the Pear Tree Inn Cape Girardeau West and Holiday Inn Express Hotel & Suites Cape Girardeau I-55. The Oak Tree Inn Dexter and Hickory House Inn are a selection of the lodgings in Dexter.

If watching sport is never far from your mind, be sure to visit Rent One Park, which can be found 60 miles (98 kilometers) to the north of Charleston. Find a Travelocity-listed hotel surrounded by the sporting action at the Fairfield Inn and Suites by Marriott Marion or the Holiday Inn Express Hotel & Suites Marion Northeast.

Travelocity's comprehensive travel guide is a good way to uncover more secrets of Charleston.

Frequently asked questions

What are the top kid-friendly hotels in Charleston?
Take some of the worries out of traveling with kids by staying in a family-friendly Charleston hotel. From special amenities to more services, these properties come with perks that'll help make your getaway smooth sailing: Quality Inn Charleston I-57 will help make your trip the most memorable one yet. It comes with lots of conveniences aimed at families, such as a swimming pool and complimentary breakfast. Also check out Super 8 by Wyndham Charleston MO. It comes with complimentary breakfast, pet-friendly facilities and lots of opportunities to spend time as a family.
Where can I find cheap hotels in Charleston?
At Travelocity you'll find really nice hotels in Charleston at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Charleston rather than in Charleston. We may find you even better rates, too.
How do I find the best Charleston hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Charleston then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Charleston?
The cheapest hotel in Charleston is $62. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Charleston?
There are 92 hotels in Charleston on Travelocity.
What are the best hotels in Charleston?
Charleston has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Charleston for you!
When is the best time to visit Charleston?
If you want the joy of a fun-filled trip in peak season, visit Charleston during March, April and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as January, February and October.
When is the cheapest time to stay in Charleston?
Based on historic data is usually the cheapest month to visit Charleston. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Charleston?
There are multiple hotels in Charleston that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Charleston. We have plenty of kid-friendly hotels in Charleston to choose from on Travelocity!
Why book a hotel in Charleston through Travelocity?
Because we have the top hotels in Charleston! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Charleston on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Charleston hotel reviews by fellow wanderers

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"Very nice hotel within walking distance to many good restaurants "
A verified traveler stayed at Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
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