Book Hotels in Puxico, MO

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Top Puxico hotels

Lake Wappapello

Lake Wappapello

2 out of 5
8005 Missouri 172 Williamsville MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $90 total per night from Apr 24 to Apr 25
$90 total
Apr 24 - Apr 25
Total with taxes and fees
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
Pet friendly. Family-friendly

Reviewed on Apr 12, 2026

Opens in a new windowLake Wappapello
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2.5 out of 5
2179 Gill Plaza Drive Dexter MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $110 total per night from May 3 to May 4
$110 total
May 3 - May 4
Total with taxes and fees
Stay at this hotel in Dexter. Popular attractions The Heritage House and Keller Veteran Memorial are located nearby.
Beautiful new location, excellent staff and amenities

Reviewed on Apr 17, 2026

Opens in a new windowHampton Inn By Hilton Dexter
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
2420 Crestwood Dr Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from May 3 to May 4
$105 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business ...
Great breakfast and friendly staff. Very pet friendly.

Reviewed on Apr 21, 2026

Opens in a new windowHampton Inn Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

3 out of 5
3109 Oak Grove Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Apr 26 to Apr 27
$114 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Very clean Great staff

Reviewed on Apr 12, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Poplar Bluff
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3 out of 5
2220 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $108 total per night from May 3 to May 4
$108 total
May 3 - May 4
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
I love the beds, the employees are all amazing

Reviewed on Apr 10, 2026

Opens in a new windowDrury Inn & Suites Poplar Bluff
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3 out of 5
2781 N Westwood Blvd Poplar Bluff MO
Fully refundable
$87 nightly
The price is $98 total per night from May 23 to May 24
$98 total
May 23 - May 24
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
The staff was friendly

Reviewed on Apr 20, 2026

Opens in a new windowHoliday Inn Poplar Bluff by IHG
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $69 total per night from Apr 24 to Apr 25
$69 total
Apr 24 - Apr 25
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed ...
Clean room

Reviewed on Apr 21, 2026

Opens in a new windowMotel 6 Poplar Bluff, MO
Dexter Inn

Dexter Inn

2.5 out of 5
1807 W Business US Highway 60 Dexter MO
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $61 total per night from May 17 to May 18
$61 total
May 17 - May 18
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk ...
Room was clean but had a musty smell. Not unbearable but annoying. Air and heat worked ok. Just need to air out the rooms and not cover up the musty smell with deodorizer. Price was reasonable.

Reviewed on Apr 12, 2026

Opens in a new windowDexter Inn
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2 out of 5
2831 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $62 total per night from May 8 to May 9
$62 total
May 8 - May 9
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Yes pet friendly

Reviewed on Apr 6, 2026

Opens in a new windowSuper 8 by Wyndham Poplar Bluff Missouri
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Puxico?
Take some of the troubles out of traveling with youngsters by choosing a family-friendly hotel in Puxico. From useful amenities to innovative services, these stays offer perks that'll make your getaway go off without a hitch: Hickory House Inn will help make your getaway the most memorable one yet. It features a variety of conveniences aimed at families, such as complimentary breakfast and pet-friendly facilities. Also consider Dexter Inn. It offers a swimming pool, pet-friendly facilities and plenty of opportunities to spend time together.
Where can I find cheap hotels in Puxico?
At Travelocity you'll find really nice hotels in Puxico at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Puxico rather than in Puxico. We may find you even better rates, too.
How do I find the best Puxico hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Puxico then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Puxico?
The cheapest hotel in Puxico is $61. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Puxico?
There are 57 hotels in Puxico on Travelocity.
What are the best hotels in Puxico?
Puxico has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Puxico for you!
When is the best time to visit Puxico?
If you want the joy of a fun-filled trip in peak season, visit Puxico during March, June and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as February, April and August.
When is the cheapest time to stay in Puxico?
Based on historic data is usually the cheapest month to visit Puxico. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Puxico?
There are multiple hotels in Puxico that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Puxico. We have plenty of kid-friendly hotels in Puxico to choose from on Travelocity!
Why book a hotel in Puxico through Travelocity?
Because we have the top hotels in Puxico! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Puxico on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

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