Book Hotels in Puxico, MO
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Top Puxico hotels

Lake Wappapello
8005 Missouri 172, Williamsville, MO
$138 nightly
The price is $146 total per night from Oct 24 to Oct 25
$146 total
Oct 24 - Oct 25
Total with taxes and fees
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
We did loose internet connection so gps did not always help but the local stores did. Also the managers answered their phones and were so helpful in many ways! I’m very glad we went.
Reviewed on Sep 28, 2025

Fairfield Inn & Suites by Marriott Poplar Bluff
3109 Oak Grove, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $115 total per night from Oct 26 to Oct 27
$115 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Everything was very good and clean and fresh we will be back
Reviewed on Oct 19, 2025

Hampton Inn Poplar Bluff
2420 Crestwood Dr, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $107 total per night from Nov 2 to Nov 3
$107 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business ...
Weekend giveaway
Very friendly staff
Reviewed on Oct 14, 2025

Drury Inn & Suites Poplar Bluff
2220 N Westwood Blvd, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $112 total per night from Nov 16 to Nov 17
$112 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
All the staff was amazing and friendly. It seems like everyone was happy to be working there.
Reviewed on Oct 17, 2025

Holiday Inn Poplar Bluff by IHG
2781 N Westwood Blvd, Poplar Bluff, MO
Fully refundable
$97 nightly
The price is $110 total per night from Nov 2 to Nov 3
$110 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Staff was friendly and accommodating. Room was quiet and clean.
Reviewed on Oct 12, 2025

Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $83 total per night from Oct 25 to Oct 26
$83 total
Oct 25 - Oct 26
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed ...
Everything we needed
Reviewed on Oct 19, 2025

Travelodge by Wyndham Dexter
1608 E Business US 60, Dexter, MO
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $93 total per night from Oct 26 to Oct 27
$93 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the business center. A restaurant, ...
Currently the best option in Dexter. The upgrade from a couple of years ago is standing up to the wear and tear of the use.
Reviewed on Sep 24, 2025

Dexter Inn
1807 W Business US Highway 60, Dexter, MO
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $67 total per night from Oct 24 to Oct 25
$67 total
Oct 24 - Oct 25
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk ...
Been a good stay every night
Reviewed on Sep 22, 2025

Super 8 by Wyndham Poplar Bluff Missouri
2831 N Westwood Blvd, Poplar Bluff, MO
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $64 total per night from Nov 4 to Nov 5
$64 total
Nov 4 - Nov 5
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
A decent hotel for the price though the breakfast was light on choices which consisted of two types of cereal and toast.
Reviewed on Sep 30, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Puxico hotel reviews by fellow wanderers

Fairfield Inn & Suites by Marriott Poplar Bluff
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Everything was very good and clean and fresh we will be back"
A verified traveler stayed at Fairfield Inn & Suites by Marriott Poplar Bluff
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