Book Hotels in Puxico, MO

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Top Puxico hotels

Lake Wappapello

Lake Wappapello

2 out of 5
8005 Missouri 172 Williamsville MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $90 total per night from Jun 8 to Jun 9
$90 total
Jun 8 - Jun 9
Total with taxes and fees
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
"Pet friendly. Family-friendly"

Reviewed on Apr 12, 2026

Opens in a new windowLake Wappapello
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2.5 out of 5
2179 Gill Plaza Drive Dexter MO
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $118 total per night from Jun 14 to Jun 15
$118 total
Jun 14 - Jun 15
Total with taxes and fees
Stay at this hotel in Dexter. Popular attractions The Heritage House and Keller Veteran Memorial are located nearby.
"Great place to stay"

Reviewed on Jun 6, 2026

Opens in a new windowHampton Inn By Hilton Dexter
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
2420 Crestwood Dr Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Jul 5 to Jul 6
$105 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business ...
"This was the best check in experience we've had. Rooms were ready and keys made when we checked in. Took 3 min. They also had all the rooms side by side we had 6 total. Will be using g Hilton owned from here on out."

Reviewed on Jun 6, 2026

Opens in a new windowHampton Inn Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

3 out of 5
3109 Oak Grove Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Jun 14 to Jun 15
$114 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Everything was clean. Staff was friendly. Fitness center was one of the best we have used."

Reviewed on Jun 3, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Poplar Bluff
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3 out of 5
2220 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Jun 14 to Jun 15
$106 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Great staff!!! Super friendly and helpful!!!"

Reviewed on Jun 5, 2026

Opens in a new windowDrury Inn & Suites Poplar Bluff
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3 out of 5
2781 N Westwood Blvd Poplar Bluff MO
Fully refundable
$97 nightly
The price is $110 total per night from Jun 28 to Jun 29
$110 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"Great staff especially Ms Wilma at the front desk!"

Reviewed on Jun 2, 2026

Opens in a new windowHoliday Inn Poplar Bluff by IHG
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $84 total per night from Jun 9 to Jun 10
$84 total
Jun 9 - Jun 10
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed ...
"The 2 guys checking us in were great. Very clean. No issues at all."

Reviewed on Jun 7, 2026

Opens in a new windowMotel 6 Poplar Bluff, MO
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

2 out of 5
1608 E Business US 60 Dexter MO
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $109 total per night from Jun 14 to Jun 15
$109 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the business center. A restaurant, ...
"Twice during our stay someone unlocked and opened the door with only the security lock stopping them."

Reviewed on Jun 5, 2026

Opens in a new windowTravelodge by Wyndham Dexter
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2 out of 5
2831 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $67 total per night from Jun 28 to Jun 29
$67 total
Jun 28 - Jun 29
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"Easy to check in"

Reviewed on May 30, 2026

Opens in a new windowSuper 8 by Wyndham Poplar Bluff Missouri
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Puxico?
Take some of the troubles out of traveling with youngsters by choosing a family-friendly hotel in Puxico. From useful amenities to innovative services, these stays offer perks that'll make your getaway go off without a hitch: Hickory House Inn will help make your getaway the most memorable one yet. It features a variety of conveniences aimed at families, such as complimentary breakfast and pet-friendly facilities. Also consider Dexter Inn. It offers a swimming pool, pet-friendly facilities and plenty of opportunities to spend time together.
Where can I find cheap hotels in Puxico?
At Travelocity you'll find really nice hotels in Puxico at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Puxico rather than in Puxico. We may find you even better rates, too.
How do I find the best Puxico hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Puxico then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Puxico?
The cheapest hotel in Puxico is $67. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Puxico?
There are 56 hotels in Puxico on Travelocity.
What are the best hotels in Puxico?
Puxico has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Puxico for you!
When is the best time to visit Puxico?
If you want the joy of a fun-filled trip in peak season, visit Puxico during March, June and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as February, April and August.
When is the cheapest time to stay in Puxico?
Based on historic data is usually the cheapest month to visit Puxico. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Puxico?
There are multiple hotels in Puxico that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Puxico. We have plenty of kid-friendly hotels in Puxico to choose from on Travelocity!
Why book a hotel in Puxico through Travelocity?
Because we have the top hotels in Puxico! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Puxico on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

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