Book Hotels in Puxico, MO

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Top Puxico hotels

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2.5 out of 5
2179 Gill Plaza Drive Dexter MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $110 total per night from Sep 13 to Sep 14
$110 total
Sep 13 - Sep 14
Total with taxes and fees
A gym is on site and the staff is available around-the-clock at the 24-hour front desk.
"Helpful staff, clean rooms, room was the right temperature, and location"

Reviewed on Sep 3, 2026

Opens in a new windowHampton Inn By Hilton Dexter
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

3 out of 5
3109 Oak Grove Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Sep 13 to Sep 14
$114 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Terrible stay, the bed was very uncomfortable. Staff was useless... Breakfast buffet wasn't fit to feed a dog, will never stay there again..."

Reviewed on Sep 1, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Poplar Bluff
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
2420 Crestwood Dr Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Sep 13 to Sep 14
$105 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business ...
"Great spot close to the college. Clean, quiet and staff were great"

Reviewed on Aug 30, 2026

Opens in a new windowHampton Inn Poplar Bluff
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from Sep 7 to Sep 8
$88 total
Sep 7 - Sep 8
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Luggage storage is provided and the front desk is staffed ...
"Staff is terrible. Check in clerk refused to check me in if I did not let him electronically scan my drivers license. I offered to let him manually enter my information but he refused. Additionally, I accidentally left our dogs’ bed in the room. When I arrived at my subsequent destination I called ..."

Reviewed on Sep 5, 2026

Opens in a new windowMotel 6 Poplar Bluff, MO
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2 out of 5
2831 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Sep 21 to Sep 22
$79 total
Sep 21 - Sep 22
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"For the price it was a very good room"

Reviewed on Aug 31, 2026

Opens in a new windowSuper 8 by Wyndham Poplar Bluff Missouri
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3 out of 5
2781 N Westwood Blvd Poplar Bluff MO
Fully refundable
$84 nightly
The price is $95 total per night from Sep 13 to Sep 14
$95 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Opens in a new windowHoliday Inn Poplar Bluff by IHG
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3 out of 5
2220 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Sep 11 to Sep 12
$106 total
Sep 11 - Sep 12
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Opens in a new windowDrury Inn & Suites Poplar Bluff
Lake Wappapello

Lake Wappapello

2 out of 5
8005 Missouri 172 Williamsville MO
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $105 total per night from Sep 7 to Sep 8
$105 total
Sep 7 - Sep 8
Total with taxes and fees
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
Opens in a new windowLake Wappapello
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

2.5 out of 5
2582 N Westwood Blvd Poplar Bluff MO
Fully refundable
$82 nightly
The price is $92 total per night from Sep 13 to Sep 14
$92 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...
Opens in a new windowComfort Inn Poplar Bluff North
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Puxico?
Take some of the troubles out of traveling with youngsters by choosing a family-friendly hotel in Puxico. From useful amenities to innovative services, these stays offer perks that'll make your getaway go off without a hitch: Hickory House Inn will help make your getaway the most memorable one yet. It features a variety of conveniences aimed at families, such as complimentary breakfast and pet-friendly facilities. Also consider Dexter Inn. It offers a swimming pool, pet-friendly facilities and plenty of opportunities to spend time together.
Where can I find cheap hotels in Puxico?
At Travelocity you'll find really nice hotels in Puxico at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Puxico rather than in Puxico. We may find you even better rates, too.
How do I find the best Puxico hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Puxico then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Puxico?
The cheapest hotel in Puxico is $79. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Puxico?
There are 56 hotels in Puxico on Travelocity.
What are the best hotels in Puxico?
Puxico has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Puxico for you!
When is the best time to visit Puxico?
If you want the joy of a fun-filled trip in peak season, visit Puxico during March, June and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as February, April and August.
When is the cheapest time to stay in Puxico?
Based on historic data is usually the cheapest month to visit Puxico. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Puxico?
There are multiple hotels in Puxico that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Puxico. We have plenty of kid-friendly hotels in Puxico to choose from on Travelocity!
Why book a hotel in Puxico through Travelocity?
Because we have the top hotels in Puxico! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Puxico on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Puxico hotel reviews by fellow wanderers

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Helpful staff, clean rooms, room was the right temperature, and location"
A verified traveler stayed at Hampton Inn By Hilton Dexter
Hampton Inn By Hilton Dexter

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