Book Hotels in Perryville, MO
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Perryville hotels

TreeLoft at BaseCamp
Reviewed on Apr 29, 2025

Hot Tub & Creek Views: Secluded Perryville Cabin
Reviewed on Jul 7, 2025

Gorgeous, downtown house!
Reviewed on Apr 7, 2025

Holiday Inn Express & Suites Perryville by IHG
Reviewed on Jul 15, 2025

Super 8 by Wyndham Perryville
Reviewed on Jul 21, 2025

Days Inn by Wyndham Perryville
Reviewed on May 29, 2025

Quality Inn Perryville I-55
Reviewed on Jun 17, 2025

Urban Lofts
Reviewed on Oct 21, 2024

New! Luxury Meets Nature - TreeRise at BaseCamp
Reviewed on Jan 11, 2025
Hotels in Perryville with star-rating
Check Perryville Hotels by Star Rating

4 Star Hotels
Perryville Hotel & Travel Guide\n
Are you planning to organize time in Southeast Missouri? Hoping to reserve somewhere to stay in or around Perryville? 3 hotels and apartments are listed within a 6-mile (10-kilometer) radius.
Travelocity-listed hotels that you can book within walking distance of Perryville's city center, are the Super 8 Perryville and Days Inn Perryville.
14 miles (23 kilometers) from the main part of Perryville, you will come across the Best Western Chester Hotel. The Microtel Inn & Suites by Wyndham Sainte Genevieve is situated 20 miles (31 kilometers) away. Two more options around Perryville include the Econo Lodge as well as the Comfort Inn Perryville.
30 miles (48 kilometers) to the west of Perryville, you will reach Farmington, where you can spend the day exploring Missouri Mines State Historic Site and Columbia Park. Farmington rooms include the Holiday Inn Express & Suites Farmington and Hampton Inn Farmington. Or, you could consider staying in Sikeston, 60 miles (98 kilometers) south of Perryville, where you can pick from the Comfort Inn And Suites and Americas Best Value Inn & Suites Sikeston. The Boot Heel Golf Club and Sikeston Depot Museum are a couple of the more frequented attractions to see for those visiting Sikeston.
Give yourself a serving of local sport by making the pilgrimage to Rent One Park, situated 50 miles (80 kilometers) to the east of Perryville. Travelocity users that like the idea of locating a hotel not too far away, book in the Fairfield Inn and Suites by Marriott Marion or Holiday Inn Express Hotel & Suites Marion Northeast.
Perryville features some great family attractions; discover more on our useful Perryville travel page.
Frequently asked questions
Recent Perryville hotel reviews by fellow wanderers

Super 8 by Wyndham Perryville
Explore More Ways to Travel with Travelocity
- Types of hotels
- Accommodation Types in Perryville
- Hotels near…
- Hotels by star rating
- Areas of Perryville
- Book on Expedia
Accommodation Types
Accommodation Types in Perryville
- Hotels with Pools in Perryville
- Hotels with Free Parking in Perryville
- Kid Friendly Hotels in Perryville
- Golf Resorts & Hotels in Perryville
- Pet Friendly Hotels in Perryville
- Historic Hotels in Perryville
- Winery Hotels in Perryville
- Hotels with Hot Tubs in Perryville
- Spa Resorts & Hotels in Perryville
- Hotels with an Indoor Pool in Perryville
An Attraction
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Hotels near Perryville Country Club
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Mark Twain National Forest
- Hotels near Sainte Genevieve Winery
- Hotels near Hawn State Park
- Hotels near Trail of Tears State Park
- Hotels near Pickle Springs Natural Area
- Hotels near Sparta Country Club
- Hotels near Crown Valley Winery
- Hotels near Popeye Museum
- Hotels near Fort Kaskaskia
- Hotels near Lake Murphysboro State Park
- Hotels near Pomona Winery
- Hotels near Weingarten Vineyard
- Hotels near Twin Oaks Vineyard & Winery
- Hotels near Sand Creek Winery
- Hotels near Silver Mine Recreation Area
- Hotels near Madison County Courthouse
- Hotels near General John A. Logan Museum
- Hotels near Lazy L Safari Park
- Hotels near Millstream Gardens Conservation Area
- Hotels near Felix Valle House State Historic Site
Star Rating
- Cape Girardeau Hotels
- Ozarks Hotels
- Farmington Hotels
- Southern Illinois Hotels
- Jackson Hotels
- Ste Genevieve Hotels
- Murphysboro Hotels
- Sparta Hotels
- Fredericktown Hotels
- Alto Pass Hotels
- Chester Hotels
- Prairie du Rocher Hotels
- Pinckneyville Hotels
- Southeast Missouri Hotels
- Bloomsdale Hotels
- Pomona Hotels
- Ava Hotels
- Jonesboro Hotels
- Marble Hill Hotels
- Central United States Hotels
- St Mary Hotels
- Baldwin Hotels
- Evansville Hotels
- Steeleville Hotels
- Gorham Hotels
- Modoc Hotels
- Great River Road Hotels
- Fruitland Hotels
- Menard Hotels
- Grand Tower Hotels
- Vergennes Hotels
- Percy Hotels
Most popular
- Hotels in Joplin
- Hotels in Jefferson City
- Pet Friendly Hotels in Branson
- Hotels in Fulton
- Hotels in Lebanon
- Hotels in Springfield
- Kid Friendly Hotels in Branson
- Hotels in St. Joseph
- Hotels in Clinton
- Hotels in Camdenton
- Hotels with an Indoor Pool in Branson
- Hotels with Hot Tubs in Branson
- Hotels in Lake Ozark
- Hotels in Poplar Bluff
- Hotels in Farmington
- Hotels in Rolla
- Hotels in Washington
- Hotels in Columbia
- Hotels in Sedalia
- Hotels in Cape Girardeau
- Hotels in Branson
- Hotels in Osage Beach
- Hotels in Hannibal