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Top Perryville hotels

New! Luxury Meets Nature - TreeRise at BaseCamp

New! Luxury Meets Nature - TreeRise at BaseCamp

Perryville MO
$463 nightly
The price is $487 total per night from Jun 16 to Jun 17
$487 total
Jun 16 - Jun 17
Total with taxes and fees
A hot tub is featured at this cabin, along with laundry facilities and barbecue grills.
"Everything was perfect! Kaci and Waylon thought of everything. Can’t wait to come back!"

Reviewed on Apr 19, 2026

Opens in a new windowNew! Luxury Meets Nature - TreeRise at BaseCamp
Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin

Perryville MO
A hot tub is featured at this cabin, along with laundry facilities and barbecue grills.
"If you need to reset and recharge, this is the place!!The property is lovely, the house is surrounded by woods and fields. The house is unique and rustic and interesting. The bathrooms and kitchen are updated and the beds are very comfy.No better place to porch sit and enjoy nature. It was a fun ..."

Reviewed on May 14, 2026

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Opens in a new windowHot Tub & Creek Views: Secluded Perryville Cabin
The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel

2 out of 5
112 W Ste Maries St Perryville MO
$147 nightly
The price is $169 total per night from Jul 8 to Jul 9
$169 total
Jul 8 - Jul 9
Total with taxes and fees
This aparthotel features a virtual front desk. Take advantage of the free self parking.
"Very nice clean room with comfortable bed and nice shower. Kitchenette was good with microwave and mini fridge, basic dishes. The owner was very easy to communicate with. Good location with Mary Jane’s restaurant bar next door had excellent food and nice atmosphere. My only small suggestion would ..."

Reviewed on May 3, 2026

Opens in a new windowThe Atrium - A Boutique Hotel
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 out of 5
2020 Jefferson St Perryville MO
Fully refundable
$101 nightly
The price is $116 total per night from Jun 11 to Jun 12
$116 total
Jun 11 - Jun 12
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Beautiful new hotel didn’t disappoint! Rey comfortable beds. Great breakfast and attentive staff keeping things filed for the best guest experience. I would definitely stop there again on my next trip through Perryville!"

Reviewed on Jun 7, 2026

Opens in a new windowHoliday Inn Express & Suites Perryville by IHG
Urban Lofts

Urban Lofts

3 out of 5
102 N Jackson St Perryville MO
Fully refundableReserve now, pay when you stay
$288 nightly
The price is $330 total per night from Jul 7 to Jul 8
$330 total
Jul 7 - Jul 8
Total with taxes and fees
This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Dry cleaning, luggage storage, and laundry facilities are also on ...
"Beautiful accommodations, close to restaurants, shopping. In the heart of city center."

Reviewed on May 29, 2026

Opens in a new windowUrban Lofts
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

2 out of 5
1119 Vincent Dr Perryville MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Jun 14 to Jun 15
$81 total
Jun 14 - Jun 15
Total with taxes and fees
This motel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"The room was ok but the bed was very hard & uncomfortable."

Reviewed on May 26, 2026

Opens in a new windowSuper 8 by Wyndham Perryville
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

2 out of 5
1500 Liberty Street Perryville MO
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $82 total per night from Jun 9 to Jun 10
$82 total
Jun 9 - Jun 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"The first room we were given had not been cleaned; dirty towels on the floor, unmade bed. The 2nd room we were given had dirty sheets. The front desk gave us new sheets which when we went to put them on the bed were stained and when removing the dirty sheets, the mattress topper had blood on it. ..."

Reviewed on Jun 1, 2026

Opens in a new windowDays Inn by Wyndham Perryville
Quality Inn Perryville I-55

Quality Inn Perryville I-55

2.5 out of 5
1517 S. Perryville Blvd. Perryville MO
Fully refundable
$76 nightly
The price is $87 total per night from Jun 10 to Jun 11
$87 total
Jun 10 - Jun 11
Total with taxes and fees
This hotel features an outdoor pool and a gym. Enjoy the hot tub and free perks like daily breakfast and free self parking. The front desk is staffed around-the-clock ...
"Got in late and left early. Felt safe and clean. I appreciated the breakfast being open early on a Saturday morning."

Reviewed on May 21, 2026

Opens in a new windowQuality Inn Perryville I-55
TreeLoft at BaseCamp

TreeLoft at BaseCamp

Perryville MO
$485 nightly
The price is $511 total per night from Jun 11 to Jun 12
$511 total
Jun 11 - Jun 12
Total with taxes and fees
A hot tub is featured at this cabin, along with a garden and barbecue grills.
Opens in a new windowTreeLoft at BaseCamp
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Perryville Hotel & Travel Guide\n

Are you planning to organize time in Southeast Missouri? Hoping to reserve somewhere to stay in or around Perryville? 3 hotels and apartments are listed within a 6-mile (10-kilometer) radius.

Travelocity-listed hotels that you can book within walking distance of Perryville's city center, are the Super 8 Perryville and Days Inn Perryville.

14 miles (23 kilometers) from the main part of Perryville, you will come across the Best Western Chester Hotel. The Microtel Inn & Suites by Wyndham Sainte Genevieve is situated 20 miles (31 kilometers) away. Two more options around Perryville include the Econo Lodge as well as the Comfort Inn Perryville.

30 miles (48 kilometers) to the west of Perryville, you will reach Farmington, where you can spend the day exploring Missouri Mines State Historic Site and Columbia Park. Farmington rooms include the Holiday Inn Express & Suites Farmington and Hampton Inn Farmington. Or, you could consider staying in Sikeston, 60 miles (98 kilometers) south of Perryville, where you can pick from the Comfort Inn And Suites and Americas Best Value Inn & Suites Sikeston. The Boot Heel Golf Club and Sikeston Depot Museum are a couple of the more frequented attractions to see for those visiting Sikeston.

Give yourself a serving of local sport by making the pilgrimage to Rent One Park, situated 50 miles (80 kilometers) to the east of Perryville. Travelocity users that like the idea of locating a hotel not too far away, book in the Fairfield Inn and Suites by Marriott Marion or Holiday Inn Express Hotel & Suites Marion Northeast.

Perryville features some great family attractions; discover more on our useful Perryville travel page.

Frequently asked questions

What are the top kid-friendly hotels in Perryville?
From thoughtful amenities to extra space, kid-friendly hotels come with features that can help turn a great family vacation into an extraordinary one. These Perryville options make vacationing with young ones a snap: You'll be well taken care of at Urban Lofts. It comes with a pillowtop mattress, a cafe and a commitment to making families feel at home. June Bugs Loft is another great choice. After a big day of exploring Perryville, come home to your comfy room and amenities like a king bed and internet access.
Where can I find cheap hotels in Perryville?
At Travelocity you'll find really nice hotels in Perryville at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Perryville rather than in Perryville. We may find you even better rates, too.
How do I find the best Perryville hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Perryville then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Perryville?
The cheapest hotel in Perryville is $81. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Perryville?
There are 175 hotels in Perryville on Travelocity.
What are the best hotels in Perryville?
Perryville has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Perryville for you!
When is the best time to visit Perryville?
If you want the joy of a fun-filled trip in peak season, visit Perryville during February, March and June. If you'd prefer the peace of off-season, book a stay during quieter months, such as November, December and January.
When is the cheapest time to stay in Perryville?
Based on historic data is usually the cheapest month to visit Perryville. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Perryville?
There are multiple hotels in Perryville that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Perryville. We have plenty of kid-friendly hotels in Perryville to choose from on Travelocity!
Why book a hotel in Perryville through Travelocity?
Because we have the top hotels in Perryville! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Perryville on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Perryville hotel reviews by fellow wanderers

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

5 out of 5
Posted 6 hours ago
Travelocity Verified Review
"Beautiful new hotel didn’t disappoint! Rey comfortable beds. Great breakfast and attentive staff keeping things filed for the best guest experience. I would definitely stop there again on my next trip through Perryville!"
A verified traveler stayed at Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHG

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