Book Hotels in De Soto, MO

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Top De Soto hotels

82 Acre Hobby Farm with Lincoln Log Cabin

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto
$257 nightly
The price is $266 total per night from Nov 4 to Nov 5
$266 total
Nov 4 - Nov 5
Total with taxes and fees
This cabin features a garden, laundry facilities, and barbecue grills.
The cabin was wonderful with many extras like snacks and coffee.

Reviewed on Oct 18, 2025

Opens in a new window82 Acre Hobby Farm with Lincoln Log Cabin
Secluded cabin on private property

Secluded cabin on private property

De Soto
This cabin features a garden, laundry facilities, and barbecue grills.
Went for a weekend to get away from the city. The cabin is located on a beautiful piece of property. Even though you are deep in the woods, we felt completely safe. The cabin is very spacious and offers the same amenities you would find in a hotel. White linens, modern kitchen, everything you need ...

Reviewed on Oct 23, 2025

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Opens in a new windowSecluded cabin on private property
Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

3 out of 5
3800 State Rt 141, Arnold, MO
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $142 total per night from Nov 9 to Nov 10
$142 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Clean room, courteous staff, good food. Overall great stay

Reviewed on Oct 28, 2025

Opens in a new windowDrury Inn & Suites St. Louis Arnold
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 out of 5
1201 Drury Ln, Arnold, MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $104 total per night from Nov 9 to Nov 10
$104 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
I am scheduled for hip surgery in 3 weeks. I was grateful for an accessible room.

Reviewed on Oct 28, 2025

Opens in a new windowPear Tree Inn St. Louis Arnold
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $62 total per night from Nov 9 to Nov 10
$62 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Yes everything was good

Reviewed on Oct 25, 2025

Opens in a new windowBaymont Inn and Suites by Wyndham Farmington, MO
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

3 out of 5
1001 Veterans Blvd, Festus, MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $112 total per night from Nov 9 to Nov 10
$112 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Our biggest concern was the sheets had dried blood stains on them. We told the clerk when we checked out

Reviewed on Oct 24, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Festus - St. Louis South
Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South

2.5 out of 5
1303 Veterans Blvd, Festus, MO
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $93 total per night from Nov 9 to Nov 10
$93 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
Mika went above and beyond even getting us ice when we checked in. As I was checking out Gary fell out used.Mika got him up and inside. Got ice and bandages. We were soon on our way.

Reviewed on Oct 17, 2025

Opens in a new windowComfort Inn Festus - St Louis South
Baymont by Wyndham Festus

Baymont by Wyndham Festus

3 out of 5
1200 W. Gannon Drive, Festus, MO
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $93 total per night from Nov 5 to Nov 6
$93 total
Nov 5 - Nov 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Families will appreciate the arcade/game room and barbecue grills. Relax with a drink at the bar/lounge and enjoy ...
I really don't want to give them a lousy review because they are trying to do repairs on the building. Beds were comfy, breakfast was good, tv works, and a nice shower!

Reviewed on Oct 13, 2025

Opens in a new windowBaymont by Wyndham Festus
Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre

2 out of 5
8 Northwood Drive Highway 67 A, Bonne Terre, MO
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $60 total per night from Nov 23 to Nov 24
$60 total
Nov 23 - Nov 24
Total with taxes and fees
An indoor pool, free self parking, and laundry facilities are featured at this motel. Guests will appreciate free perks like on-the-go breakfast and WiFi in ...
Good stay
I was a bit surprised to find out upon arrival that the motel changed hands since my last visit and went to all non smoking rooms. It was booked as smoking and I wasn't notified of the change. That aside, it was a good stay. The new staff was friendly and helpful. Even though the pool heater wasn't ...

Reviewed on Oct 11, 2025

Opens in a new windowSuper 8 by Wyndham Bonne Terre
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

De Soto Hotel & Travel Guide\n

Dreaming about exploring De Soto? Travelocity has no hotels and apartments, however, there are 4 places to rest and relax within an easy drive of De Soto.

The nearest Travelocity-listed accommodation is the Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, Missouri, 9 miles (15 kilometers) from the middle of De Soto. Another Travelocity accommodation option is the Lexington Inn - Shalimar Plaza & Conference Center, situated in Missouri, 10 miles (15 kilometers) from the middle of De Soto.

The Comfort Inn is 10 miles (15 kilometers) outside the city center of De Soto. An alternative accommodation option is the Super 8 Pevely, which can be found approximately 14 miles (22 kilometers) away. The Super 8 Potosi Mo as well as the Super 8 Bonne Terre are two other Travelocity-listed accommodation options worth checking out around De Soto.

There are various Travelocity-registered hotels in Pilot Knob, which is situated 35 miles (55 kilometers) south of De Soto. The Fort Davidson Hotel and Shepherd Mountain Inn are a few of the establishments here.

Make sure you get your fix of local sport by making the journey to Busch Stadium, which is 40 miles (64 kilometers) to the northeast of De Soto. Enlightened travelers wanting to find a Travelocity-listed room near to the action can choose from the Four Seasons Hotel St Louis or the Grand Center Inn.

Lambert-St. Louis International Airport is a practical arrival point for flights, and is situated 45 miles (72 kilometers) away from De Soto. Travelocity-listed hotels close to Lambert-St. Louis International Airport include Marriott St. Louis Airport and Holiday Inn St. Louis-Airport.

Frequently asked questions

What are the top kid-friendly hotels in De Soto?
From carefully considered amenities to rooms with bunk beds, kid-friendly hotels are equipped with features that can help transform a nice family vacation into a fantastic one. These De Soto properties make vacationing with your youngsters a snap: Put your bags down at NEW! Traditional Country Home in De Soto w/ Yard!. It comes with a firepit, a fireplace and a flair for making families feel at home. Beautiful 2 bedroom unit at resort, sleeps 6 is also a great choice. After a fun day of exploring, return to your comfy room and perks like a sauna and a king bed.
Where can I find cheap hotels in De Soto?
At Travelocity you'll find really nice hotels in De Soto at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near De Soto rather than in De Soto. We may find you even better rates, too.
How do I find the best De Soto hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in De Soto then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in De Soto?
The cheapest hotel in De Soto is $60. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in De Soto?
There are 169 hotels in De Soto on Travelocity.
What are the best hotels in De Soto?
De Soto has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in De Soto for you!
When is the best time to visit De Soto?
If you want the joy of a fun-filled trip in peak season, visit De Soto during March, April and May. If you'd prefer the peace of off-season, book a stay during quieter months, such as June, October and November.
When is the cheapest time to stay in De Soto?
Based on historic data is usually the cheapest month to visit De Soto. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in De Soto?
There are multiple hotels in De Soto that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to De Soto. We have plenty of kid-friendly hotels in De Soto to choose from on Travelocity!
Why book a hotel in De Soto through Travelocity?
Because we have the top hotels in De Soto! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in De Soto on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent De Soto hotel reviews by fellow wanderers

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

5 out of 5
Posted 5 days ago
Travelocity Verified Review
"Clean room, courteous staff, good food. Overall great stay"
A verified traveler stayed at Drury Inn & Suites St. Louis Arnold
Drury Inn & Suites St. Louis Arnold

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