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Top De Soto hotels

82 Acre Hobby Farm with Lincoln Log Cabin
Reviewed on Jun 1, 2025

Secluded cabin on private property
Reviewed on Jul 15, 2025

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Reviewed on Jul 14, 2025

Drury Inn & Suites St. Louis Arnold
Reviewed on Jul 5, 2025

Pear Tree Inn St. Louis Arnold
Reviewed on Jul 21, 2025

Baymont Inn and Suites by Wyndham Farmington, MO
Reviewed on Jul 20, 2025

Comfort Inn Festus - St Louis South
Reviewed on Jul 19, 2025

Pool, Lake & Patio: Sweeping De Soto Estate

Lakeside Private Villa | 5-Hole Golf On-Site
Reviewed on Mar 28, 2023
De Soto Hotel & Travel Guide\n
Dreaming about exploring De Soto? Travelocity has no hotels and apartments, however, there are 4 places to rest and relax within an easy drive of De Soto.
The nearest Travelocity-listed accommodation is the Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, Missouri, 9 miles (15 kilometers) from the middle of De Soto. Another Travelocity accommodation option is the Lexington Inn - Shalimar Plaza & Conference Center, situated in Missouri, 10 miles (15 kilometers) from the middle of De Soto.
The Comfort Inn is 10 miles (15 kilometers) outside the city center of De Soto. An alternative accommodation option is the Super 8 Pevely, which can be found approximately 14 miles (22 kilometers) away. The Super 8 Potosi Mo as well as the Super 8 Bonne Terre are two other Travelocity-listed accommodation options worth checking out around De Soto.
There are various Travelocity-registered hotels in Pilot Knob, which is situated 35 miles (55 kilometers) south of De Soto. The Fort Davidson Hotel and Shepherd Mountain Inn are a few of the establishments here.
Make sure you get your fix of local sport by making the journey to Busch Stadium, which is 40 miles (64 kilometers) to the northeast of De Soto. Enlightened travelers wanting to find a Travelocity-listed room near to the action can choose from the Four Seasons Hotel St Louis or the Grand Center Inn.
Lambert-St. Louis International Airport is a practical arrival point for flights, and is situated 45 miles (72 kilometers) away from De Soto. Travelocity-listed hotels close to Lambert-St. Louis International Airport include Marriott St. Louis Airport and Holiday Inn St. Louis-Airport.
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Postcard Cabins St. Francois
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An Attraction
- Hotels near Mississippi River
- Hotels near Mark Twain National Forest
- Hotels near Meramec State Park
- Hotels near Meramec River
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- Hotels near Hawn State Park
- Hotels near Big River
- Hotels near Pickle Springs Natural Area
- Hotels near St. Francois State Park
- Hotels near Villa Antonio Winery
- Hotels near St. Joe State Park
- Hotels near Crown Pointe Golf Club
- Hotels near Weingarten Vineyard
- Hotels near Persimmon Ridge Winery
- Hotels near Robertsville State Park
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