What to do In Southeast Missouri, MO
Explore thousands of activities, attractions and tours with free cancellation and no added fees.
Design your experience with airport transfers, excursions, day tours & more.
Access exclusive deals, only with the Travelocity app
Explore activities in Southeast Missouri by interest
Things to do

Night Ghost Tour of Pythian Castle in Springfield Missouri

History Tour of Pythian Castle in Springfield Missouri
Places To Go In Southeast Missouri
Welcome, traveler, to Southeast Missouri. Your journey has landed you here, and new adventures are calling your name. Now that you’ve arrived, you can stay in the safety and comfort of your hotel and watch the world spin past…or you can embrace this new place you’ve come to. Learn its streets. Meet its people. Learn its history. Your hand is already on the doorknob, isn’t it?
Things to Do in Southeast Missouri
You’ll not be wanting for things to do in Southeast Missouri. Explore the downtown area in search of museums and boutiques…or that next delicious meal. What tickles your fancy? A delectable five-course supper at the restaurant you’ve been hearing about? Or perhaps you’d rather read the paper while sipping hot coffee at one of the cafes scattered throughout town. Take in a show at the theatre, or just walk along down the main thoroughfare, watching people wander past.
Why spend hours ruminating over what to do in Southeast Missouri? Let the possibilities wash over you as you explore this new region. Move out on foot and get to know the area on a more personal level. Find that perfect souvenir at one of the smaller shops, or reinvent your entire artistic aesthetic at your new favorite gallery.
Is the wind whispering suggestions in your mind? Rent a car and take it out beyond city limits and into the wild blue yonder. Explore the smaller cities and towns past the border, and get to know the stories behind them. Visit a county fair and let childhood memories wash over you as cotton candy melts in your mouth. Sample hand-made jam at a stop on a forgotten highway, or let the hustle and bustle of modern life sweep you away as you lose yourself in the organized chaos of a modern metropolis. Your choices are endless—and so are the adventures to come.
When you book your journey with Travelocity, you’re never far from Southeast Missouri attractions. After all, the money you save when you plan a trip with us is best spent along the way. Whether it’s the roar of the city you crave, or the quiet solitude that comes with a simpler getaway, everything you need to get started is right here.
Stay near popular Southeast Missouri attractions
More ways to wander Southeast Missouri
Explore More Ways to Travel with Travelocity
- Privatevacationhomes in Madison County
- Caravanparks in Madison County
- Hotels in Marble Hill
- Hotels in Perryville
- Apartments in Piedmont
- Cabins in Piedmont
- Petfriendly in Piedmont
- Hotels in Piedmont
- Motels in Piedmont
- Cabins in Pilot Knob
- Cottages in Pilot Knob
- Lodges in Pilot Knob
- Motels in Pilot Knob
- Drury Inn & Suites Poplar Bluff
- Motel 6 Poplar Bluff Mo
- Hotels in Poplar Bluff
- Hotels near Silver Mine Recreation Area
- Agritourism in Southeast Missouri
- Apartments in Southeast Missouri
- Bedandbreakfast in Southeast Missouri
- Cabins in Southeast Missouri
- Condos in Southeast Missouri
- Aparthotels in Southeast Missouri
- Historical in Southeast Missouri
- Balcony in Southeast Missouri
- Hottub in Southeast Missouri
- Smoking in Southeast Missouri
- Waterslide in Southeast Missouri
- Petfriendly in Southeast Missouri
- Romantic in Southeast Missouri
- Winery in Southeast Missouri
- Houseboats in Southeast Missouri
- Lodges in Southeast Missouri
- Motels in Southeast Missouri
- Caravanparks in Southeast Missouri
- Villas in Southeast Missouri
- Hotels near Taum Sauk Mountain State Park
- Hotels in Van Buren
- Hotels near Walnut Hollow Lake
- Cabins in Wappapello
- Cabins in Wayne County
- Caravanparks in Wayne County
- Lodges in Arcadia
- Hotels in Arcadia
- Bedandbreakfast in Arcadia
- Motels in Annapolis
- Lodges in Annapolis
- Hotels in Annapolis
- Rustic River Cabin Getaway
- Panther Den Cabin is located 4 miles from Hwy K Campground
- Hillside Cabin 2 Annapolis MO Black River
- Cottages in Annapolis
- Cabins in Annapolis
- Bedandbreakfast in Annapolis
- Hotels in Cape Girardeau
- Hotels in Des Arc
- Hotels near Elephant Rocks State Park
- Arcadia Valley Bungalows
- Fort Davidson Hotel
- Hottub in Farmington
- Madison Inn Lodge
- Shepherd Mountain Inn
- Hotels in Farmington
- Bedandbreakfast in Fredericktown
- Cabins in Fredericktown
- Aparthotels in Fredericktown
- Pool in Fredericktown
- Petfriendly in Fredericktown
- Hotels in Fredericktown
- Privatevacationhomes in Fredericktown
- Hotels in Greenville
- Bedandbreakfast in Ironton
- Cabins in Ironton
- Cottages in Ironton
- Hottub in Ironton
- Hotels in Ironton
- Lodges in Ironton
- Motels in Ironton
- Hotels near Johnson'S Shut-Ins State Park
- Hotels near K Bridge Recreation Area
- Cabins in Lesterville
- Hotels in Lesterville
- Bedandbreakfast in Madison County




