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Featured Southeast Missouri Lodges

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Cedar Stone Lodge

Cedar Stone Lodge

3.0 out of 5.0 Hwy 19, Eminence, MO
This lodge doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace, a garden, and a picnic area are also on offer.
 
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Spring Lake Ranch has a Private, Rustic Lodge Perfect for Family/group Retreats!

Spring Lake Ranch has a Private, Rustic Lodge Perfect for Family/group Retreats!

Potosi, MO
This lodge features an outdoor pool and a spa tub. A garden is also provided.
 

Southeast Missouri Mountain Accommodation

$99
Echo Bluff State Park

Echo Bluff State Park

2.5 out of 5.0 34489 Echo Bluff Dr, Salem, MO
5/5
(1 Reviews)
A restaurant, free self parking, and a 24-hour front desk are among this hotel's amenities. WiFi in public areas is free. A grocery/convenience store, a lobby fireplace, and a picnic area are also on offer.
 
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Eagle's Landing River Resort

Eagle's Landing River Resort

2.5 out of 5.0 16273 Salter Lane, Eminence, MO
A restaurant and a bar/lounge are featured at this motel. Guests will appreciate free perks like free self parking and WiFi in public areas.
 

Southeast Missouri Ski Accommodation

$109
Holiday Inn Club Vacations Timber Creek Resort

Holiday Inn Club Vacations Timber Creek Resort

3.5 out of 5.0 4800 U.S. Highway 67, De Soto, MO
5/5
(1 Reviews)
This condo resort's 2 outdoor tennis courts and fitness center are among the featured amenities. There's fun for all ages with mini golf and a playground, and barbecue grills are available on site. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi.
 
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Book a Lodge in Southeast Missouri

For you, no getaway is complete without immersing yourself in the great outdoors. Over the years you’ve spent time fishing at stunning blue lakes, waking up at dawn to watch the sun rise in dense forests, and even hiking to the top of mountains just to get an incredible view. On your next trip out of town, make yourself right at home in nature by booking your stay at a lodge resort in Southeast Missouri.

Southeast Missouri is known for its natural wonders. Whether you plan to spend your entire trip hiking, biking, or simply meditating outdoors, you’ll be happy to return to one of our lodge rentals at the end of the day. Your room will be ultra-comfortable, but we’re fairly certain you won’t spend too much time inside. Reach into your mini-fridge and grab the iced coffee you stashed for your morning hike—there’s nothing like caffeinating while taking in sweeping views of towering trees and spotting birds.

Choose from a variety of lodging offered in Southeast Missouri, from rustic rentals that will fit the entire family (and maybe even a furry friend or two) to luxury lodges perfect for impressing your significant other. Spa tubs and kitchenettes? Why yes, we’ll join you for a romantic breakfast.

Searching for some peace and quiet? Trying to host an epic family reunion? Whatever brings you to Southeast Missouri, there’s a lodge that’ll make you feel right at home. Trust Travelocity to help you find the place that makes your wandering heart sing.

Top Trending Hotels in Southeast Missouri

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$69
Auburn Place Hotel And Suites

Auburn Place Hotel And Suites

2.5 out of 5.0 3265 William St, Cape Girardeau, MO
Situated in Cape Girardeau, this hotel is 2.5 mi (4 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Shawnee National Forest and Isle Casino Cape Girardeau. Southeast Missouri State University and Cape Girardeau Conservation Nature Center are also within 6 mi (10 km).
 
$99
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 out of 5.0 3351 Percy Drive, Cape Girardeau, MO
Situated in Cape Girardeau, this hotel is 2.3 mi (3.7 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Isle Casino Cape Girardeau and Shawnee National Forest. Cape Girardeau Conservation Nature Center and Southeast Missouri State University are also within 6 mi (10 km).
 
$63
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5.0 103 Cape West Pkwy, Cape Girardeau, MO
Situated in a rural location, this hotel is 2.8 mi (4.5 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Isle Casino Cape Girardeau and Shawnee National Forest. Southeast Missouri State University and Cape Girardeau Conservation Nature Center are also within 6 mi (10 km).
 
$63
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5.0 3248 William St, Cape Girardeau, MO
Located in the heart of Cape Girardeau, this hotel is 2.4 mi (3.9 km) from Cape Splash Family Aquatic Center and within 6 mi (10 km) of Isle Casino Cape Girardeau and Shawnee National Forest. Southeast Missouri State University and Cape Girardeau Conservation Nature Center are also within 6 mi (10 km).
 

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.