Cheap Flights to Sikeston from $35
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How Much Does it Cost To Fly To Sikeston?
The cheapest prices found with in the last 7 days for return flights were $58 and $35 for one-way flights to Sikeston for the period specified. Prices and availability are subject to change. Additional terms apply
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$58 Roundtrip, found 3 days ago
$58
Roundtrip
found 3 days ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DFW | St. Louis | May 26 to June 10 | $58 |
| ATL | St. Louis | May 27 to June 3 | $107 |
| EWR | St. Louis | May 12 to May 13 | $154 |
| DFW | Scott City | June 5 to June 12 | $178 |
| LAX | St. Louis | May 28 to May 31 | $215 |
| ATL | West Paducah | May 14 to May 17 | $299 |
| LAX | West Paducah | June 1 to June 8 | $362 |
| JFK | Scott City | May 5 to May 6 | $426 |
| TPA | Scott City | May 20 to May 27 | $428 |
| SEA | West Paducah | May 5 to May 19 | $481 |
| SEA | Scott City | May 10 to May 14 | $687 |
| PHL | West Paducah | May 4 to May 8 | $729 |
| LAX | Scott City | April 30 to May 3 | $774 |
| DEN | West Paducah | May 14 to May 17 | $784 |
| FCO | St. Louis | May 7 to May 10 | $976 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| TTN | St. Louis | April 26 to April 28 | $241 |
| DFW | St. Louis | April 26 to April 30 | $271 |
| LGA | St. Louis | April 26 to April 30 | $307 |
| LGA | St. Louis | April 26 to April 30 | $307 |
| ATL | St. Louis | April 24 to April 26 | $312 |
| DEN | St. Louis | April 24 to April 25 | $322 |
| LAX | St. Louis | April 26 to April 27 | $332 |
| TPA | St. Louis | April 24 to April 27 | $485 |
| SEA | St. Louis | April 24 to April 26 | $522 |
| DFW | Scott City | April 25 to April 27 | $1,077 |
Sikeston Flight Information
Traveling to | Sikeston |
|---|---|
Lowest Price | $58 |
Number of Airlines Serving | |
Airlines Serving | Frontier Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Sikeston Accommodation Deals
Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
$72 nightly
The price is $81 total per night from May 17 to May 18
$81 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
Breakfast was hot and manned by a friendly staff member. Room was clean and met my needs.
Reviewed on Apr 9, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$61 nightly
The price is $70 total per night from Apr 26 to Apr 27
$70 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,000 reviews)
I stayed in Room 214. The room was clean, but there were some furniture and appliance problems. The smoke detector in the off room with the sofa was disconnected from the ceiling and hanging by its wires. The caulking around the sink in the bathroom was coming a loose. The hair drier was melted at ...
Reviewed on Apr 21, 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
$105 nightly
The price is $118 total per night from Apr 26 to Apr 27
$118 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,000 reviews)
Yes
Reviewed on Apr 20, 2026
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Eagle Inn Charleston
2811 East Marshall Street Charleston MO
$55 nightly
The price is $61 total per night from May 2 to May 3
$61 total
May 2 - May 3
Total with taxes and fees
Stay at this motel in Charleston. Enjoy free WiFi, free parking, and a health club.
6.6/10 (106 reviews)
Great
Reviewed on Apr 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Sikeston
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$61 nightly
The price is $70 total per night from Apr 26 to Apr 27
$70 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,000 reviews)
I stayed in Room 214. The room was clean, but there were some furniture and appliance problems. The smoke detector in the off room with the sofa was disconnected from the ceiling and hanging by its wires. The caulking around the sink in the bathroom was coming a loose. The hair drier was melted at ...
Reviewed on Apr 21, 2026
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau MO
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Riverfront Park and eDen Spa & Salon are located ...
10/10 Exceptional! (224 reviews)
Great location, quality bedding and pillows, and other comfortable amenities for a short getaway in historic downtown Cape Girardeau. Excellent value!
Reviewed on Dec 15, 2025
Quality Inn Cape Girardeau North
2011 North Kingshighway Cape Girardeau MO
$63 nightly
The price is $71 total per night from Apr 30 to May 1
$71 total
Apr 30 - May 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
7.2/10 Good! (730 reviews)
It was good, but a noticeable hole in the wall above the toilet paper.
Reviewed on Apr 17, 2026
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Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$100 nightly
The price is $115 total per night from Apr 29 to Apr 30
$115 total
Apr 29 - Apr 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,005 reviews)
👍
Reviewed on Apr 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Sikeston
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$100 nightly
The price is $115 total per night from Apr 29 to Apr 30
$115 total
Apr 29 - Apr 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,005 reviews)
👍
Reviewed on Apr 19, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
$77 nightly
The price is $88 total per night from Apr 26 to Apr 27
$88 total
Apr 26 - Apr 27
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,004 reviews)
The staff were all wonderful and the breakfast was good. Our room door was propped open when we arrived, which was kind of off-putting. Also, the property could use some upgrades. I think the bathtub was clean, just old so kind of dingy looking. The elevator was out of order.
Reviewed on Apr 20, 2026
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
$94 nightly
The price is $106 total per night from May 3 to May 4
$106 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,006 reviews)
Wonderful stay, very spacious room, clean, super comfortable beds, breakfast was delicious!
Reviewed on Apr 20, 2026
Save an average of 15% on thousands of hotels when you're signed in
Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd Jackson MO
$92 nightly
The price is $100 total per night from May 6 to May 7
$100 total
May 6 - May 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Cape Girardeau Conservation Nature ...
8.2/10 Very Good! (762 reviews)
It was way below average and was not a cheap property to stay at. Very dirty room, bathroom was disgusting. Breakfast was mediocre. Pool area was even dirty. Front desk clerk was also doing the breakfast area. Wore the same gloves from food area, to front desk, back to food area.
Reviewed on Apr 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Sikeston Flight and Hotel Packages
Sikeston flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Need a Car For After Your Flight?
Special
Saint Ann, Missouri, USA
$47
$128 total
found 1 day ago
Midsize
St Louis, Missouri, USA
$48
$124 total
found 21 hours ago
Compact
St Louis, Missouri, USA
$48
$124 total
found 21 hours ago
Economy
St Louis, Missouri, USA
$48
$124 total
found 21 hours ago
Frequently asked questions
Plane Tickets To Sikeston
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