Cheap Flights to Southeast Missouri from $35
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How Much Does it Cost To Fly To Southeast Missouri?
The cheapest prices found with in the last 7 days for return flights were $94 and $35 for one-way flights to Southeast Missouri for the period specified. Prices and availability are subject to change. Additional terms apply
LAS
Harry Reid Intl.
STL
Lambert-St. Louis Intl.
$94 Roundtrip, found 13 hours ago
$94
Roundtrip
found 13 hours ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| BWI | St. Louis | October 31 to November 7 | $156 |
| EWR | St. Louis | November 7 to November 14 | $156 |
| MCI | St. Louis | November 12 to November 17 | $156 |
| CMH | St. Louis | November 3 to November 8 | $168 |
| LAX | St. Louis | December 30 to January 10 | $199 |
| BWI | Scott City | December 9 to December 10 | $435 |
| BWI | Marion | November 18 to November 19 | $445 |
| LAX | West Paducah | December 6 to December 13 | $502 |
| DCA | Marion | November 18 to November 19 | $524 |
| STL | Marion | November 3 to November 4 | $544 |
| STL | West Paducah | November 26 to December 2 | $545 |
| EWR | West Paducah | December 22 to December 29 | $603 |
| MSP | West Paducah | October 29 to November 7 | $623 |
| LAX | Marion | October 31 to November 4 | $659 |
| MSP | Scott City | October 31 to November 3 | $1,081 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| BWI | St. Louis | October 26 to October 31 | $168 |
| EWR | St. Louis | October 26 to October 31 | $202 |
| MCI | St. Louis | October 24 to October 30 | $212 |
| SAT | St. Louis | October 24 to October 26 | $221 |
| LAX | St. Louis | October 25 to October 28 | $265 |
| MSY | St. Louis | October 26 to November 1 | $344 |
| CMH | St. Louis | October 25 to November 6 | $411 |
| MSP | St. Louis | October 26 to October 27 | $585 |
| DCA | St. Louis | October 25 to October 28 | $606 |
| DCA | Marion | October 24 to October 25 | $928 |
Southeast Missouri Flight Information
Traveling to | Southeast Missouri |
|---|---|
Lowest Price | $94 |
Number of Airlines Serving | |
Airlines Serving | Frontier Airlines, United |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Southeast Missouri Accommodation Deals
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
$79 nightly
The price is $83 total per night from Oct 24 to Oct 25
$83 total
Oct 24 - Oct 25
Total with taxes and fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,018 reviews)
"The Light was on when I needed it the most."
Reviewed on Oct 15, 2025
Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
$75 nightly
The price is $86 total per night from Oct 25 to Oct 26
$86 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,012 reviews)
"The Pear Tree was clean, comfortable, and the staff were extremely friendly!"
Reviewed on Oct 13, 2025
Super 8 by Wyndham Farmington
930 Valley Creek Dr, Farmington, MO
$54 nightly
The price is $61 total per night from Oct 22 to Oct 23
$61 total
Oct 22 - Oct 23
Total with taxes and fees
Book a stay at this business-friendly motel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (594 reviews)
"Check in staff seemed a little overwhelmed and took them a minute to find my reservation. Could’ve been a little more friendly."
Reviewed on Oct 14, 2025
Save an average of 15% on thousands of hotels when you're signed in
Super 8 by Wyndham Pevely
1711 Highway Z, Pevely, MO
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
5.6/10 (827 reviews)
Adequate
"Hotel is in rough shape…but if you just need a place to sleep for the night it will fulfill that. Hotel needs a major revamping."
Reviewed on May 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Southeast Missouri
Super 8 by Wyndham Pevely
1711 Highway Z, Pevely, MO
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
5.6/10 (827 reviews)
Adequate
"Hotel is in rough shape…but if you just need a place to sleep for the night it will fulfill that. Hotel needs a major revamping."
Reviewed on May 17, 2025
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
$79 nightly
The price is $83 total per night from Oct 24 to Oct 25
$83 total
Oct 24 - Oct 25
Total with taxes and fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,018 reviews)
"The Light was on when I needed it the most."
Reviewed on Oct 15, 2025
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
$63 nightly
The price is $72 total per night from Nov 2 to Nov 3
$72 total
Nov 2 - Nov 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,008 reviews)
"The staff was very professional, kind and accommodating."
Reviewed on Oct 12, 2025
Save an average of 15% on thousands of hotels when you're signed in
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a water park, and laundry facilities. Popular attractions Riverfront Park and eDen Spa & Salon are ...
9.8/10 Exceptional! (170 reviews)
"Great placeClean amenities bed comfortable location view all excellent Tea room downstairs a nice extra too"
Reviewed on Sep 21, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Southeast Missouri
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
$90 nightly
The price is $103 total per night from Oct 26 to Oct 27
$103 total
Oct 26 - Oct 27
Total with taxes and fees
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,010 reviews)
"Clean. Happy hour at 530, decent breakfast options"
Reviewed on Oct 16, 2025
Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
$75 nightly
The price is $86 total per night from Oct 25 to Oct 26
$86 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,012 reviews)
"The Pear Tree was clean, comfortable, and the staff were extremely friendly!"
Reviewed on Oct 13, 2025
Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
$84 nightly
The price is $96 total per night from Nov 9 to Nov 10
$96 total
Nov 9 - Nov 10
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,008 reviews)
"Clean and roomy room. Friendly and helpful staff. Great breakfast."
Reviewed on Oct 16, 2025
Save an average of 15% on thousands of hotels when you're signed in
Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
$90 nightly
The price is $102 total per night from Oct 26 to Oct 27
$102 total
Oct 26 - Oct 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,004 reviews)
Pleasant surprise in Cape Girardeau
"Very clean and comfortable. Good value for the money. Restaurants close by, some within walking distance."
Reviewed on Oct 6, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Southeast Missouri Flight and Hotel Packages
Southeast Missouri flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Don't see what you're looking for?
See all available trips from Fargo to Southeast Missouri
View all tripsNeed a Car For After Your Flight?
Economy
Chevrolet Spark or similar
Compact
Ford Focus or similar
Midsize
Toyota Corolla or similar
SUV
Jeep Compass or similar
Frequently asked questions
Plane Tickets To Southeast Missouri
Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Southeast Missouri. Browse through our inventory to explore a wide range of cheap flights to Southeast Missouri to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Southeast Missouri as you anxiously await to exit the plane and explore what Southeast Missouri has to offer. Considering all the amazing local food and culture in Southeast Missouri, we won't hold this against you.
When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Southeast Missouri to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Southeast Missouri without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Southeast Missouri with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Southeast Missouri today!
More Ways To Wander
Southeast Missouri Hotels
Find the perfect hotel after your flight
Southeast Missouri Vacation Rentals
Great Deals on alternative accommodations
Southeast Missouri Car Rentals
Affordable cars to get you around town
Southeast Missouri Vacations
Save more by combining flights, hotels and cars
Things to do in Southeast Missouri
Activities, attractions and tours
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