Find a Hotel in Texas Medical Center

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top hotels in Texas Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
$108 nightly
The price is $126 total per night from Jul 1 to Jul 2
$126 total
Jul 1 - Jul 2
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Excellent location, cleanliness and safety. Great for families! The breakfast is decent and there is enough seating for all. The pool is not huge and can get crowded. It does have a bar though."

Reviewed on Jun 12, 2026

Opens in a new windowHyatt Place Houston Medical Center
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
$183 nightly
The price is $214 total per night from Jul 5 to Jul 6
$214 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"NICE HOTEL IN THE NICE ARE, CLOSE TO THE PARKS AND THE TRAIN TO MOVE ARROUND. ALL MUSEUM ARE REALLY CLOSE."

Reviewed on Jun 8, 2026

Opens in a new windowInterContinental Houston by IHG
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

3 out of 5
7329 FANNIN STREET Houston TX
$127 nightly
The price is $149 total per night from Jul 5 to Jul 6
$149 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like buffet breakfast and WiFi in public areas. You'll ...
"It was very difficult for us after driving 6 hours we stayed in level where the dogs at we didn’t sleep with so many barking"

Reviewed on Jun 8, 2026

Opens in a new windowHyatt House Houston Medical Center
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

3 out of 5
6840 Almeda Rd Houston TX
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $134 total per night from Jul 12 to Jul 13
$134 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"."

Reviewed on Jun 9, 2026

Opens in a new windowHilton Garden Inn Houston Medical Center, TX
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $195 total per night from Jul 11 to Jul 12
$195 total
Jul 11 - Jul 12
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"The room was very clean somewhat there was hai inside the bathtub so I wasn’t able to use it. Air conditioner didn’t get cold it took 1 hour before we feel the coldness. It was hard to find the parking we found the easiest parking valet when we were about to leave. But overall it was very neat and ..."

Reviewed on Jun 9, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $185 total per night from Jul 13 to Jul 14
$185 total
Jul 13 - Jul 14
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
"Clean property, rooms are a nice size, clean and very bright. Staff is friendly, pool was clean and I would stay at the property again!"

Reviewed on Jun 11, 2026

Opens in a new windowBlossom Hotel Houston, Curio Collection by Hilton
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from Jul 5 to Jul 6
$117 total
Jul 5 - Jul 6
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...
"Good"

Reviewed on Jun 10, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park

2.5 out of 5
1715 Old Spanish Trl Houston TX
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from Jul 5 to Jul 6
$117 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. Self parking, a business ...
"Stayed here during a business trip and had one of the worst hotel experiences I’ve had. One of my coworkers left her room in the morning with the bathroom sink completely fine. While we were away, housekeeping found the sink broken. Instead of investigating what happened, management immediately decided ..."

Reviewed on Jun 10, 2026

Opens in a new windowHampton Inn & Suites Houston Medical Center NRG Park
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Jul 5 to Jul 6
$143 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Not enough electrical outlets at the head of the bed In room coffee lack there of Carpets stained Limited parking Delicious cookies Scarce luggage carriages Nice lobby but wish for higher seating"

Reviewed on Jun 9, 2026

Opens in a new windowDoubleTree by Hilton Houston Medical Center Hotel & Suites
Don't see what you're looking for?
See all available properties in Texas Medical Center
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Texas Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Texas Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Texas Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Texas Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Texas Medical Center hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity