Find a Hotel in Texas Medical Center

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Top hotels in Texas Medical Center

InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
$173 nightly
The price is $203 total per night from Jan 18 to Jan 19
$203 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Bar snacks were delicious and service was very good. The hotel was very comfortable and our room was nice.

Reviewed on Jan 12, 2026

Opens in a new windowInterContinental Houston by IHG
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $162 total per night from Feb 15 to Feb 16
$162 total
Feb 15 - Feb 16
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
I loved everything

Reviewed on Jan 11, 2026

Opens in a new windowBlossom Hotel Houston, Curio Collection by Hilton
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Feb 5 to Feb 6
$138 total
Feb 5 - Feb 6
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the hot tub ...
Everything was great

Reviewed on Jan 13, 2026

Opens in a new windowHyatt Place Houston Medical Center
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
$183 nightly
The price is $212 total per night from Jan 18 to Jan 19
$212 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Great hotel - feels like a moment of vacation while going to the medical center

Reviewed on Jan 10, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
$96 nightly
The price is $112 total per night from Jan 22 to Jan 23
$112 total
Jan 22 - Jan 23
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
The staff was friendly and accommodating. The furniture in the room was a little hit or miss. Stayed in a room with a sofa, the first room did not have a sofa, the second room had a slightly leaky sink. The staff moved me no problem. The sheets were wonderful and the coffee machine was great. Love ...

Reviewed on Jan 16, 2026

Opens in a new windowClub Quarters Hotel Downtown, Houston
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
$159 nightly
The price is $186 total per night from Jan 23 to Jan 24
$186 total
Jan 23 - Jan 24
Total with taxes and fees
This hotel features an outdoor pool, A 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
Great stay

Reviewed on Jan 13, 2026

Opens in a new windowThe Royal Sonesta Houston Galleria
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $96 total per night from Feb 1 to Feb 2
$96 total
Feb 1 - Feb 2
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas and free ...
Staff did a great job after Doubletree hilton or expedia did not fufill a reservation i made days before.

Reviewed on Jan 15, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $98 total per night from Feb 1 to Feb 2
$98 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Very nice and clean and comfortable

Reviewed on Jan 11, 2026

Opens in a new windowDoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $139 total per night from Jan 23 to Jan 24
$139 total
Jan 23 - Jan 24
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like a free area shuttle. Valet parking, a business center, ...
Great location

Reviewed on Jan 14, 2026

Opens in a new windowDoubleTree by Hilton Hotel & Suites Houston by the Galleria
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Texas Medical Center Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Texas Medical Center area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Texas Medical Center to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Texas Medical Center are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

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