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Top Hillsboro hotels

The Wildwood Hotel
Great hotel in a great neighborhood
Reviewed on Nov 9, 2025

River City Casino & Hotel
Clean room, good Pizza.
Reviewed on Nov 8, 2025

Holiday Inn St Louis SW - Route 66 by IHG
Staff were friendly and accommodating. Someone found my phone in the parking lot and they kept it safe for me until I could get it. Rooms are comfortable and not noisy.
Reviewed on Nov 2, 2025

Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Spotless room great mattress and pillows and super friendly staff
Reviewed on Nov 7, 2025

Best Western St. Louis-Kirkwood Route 66
Yes, Very nice and comfortable stay.. Clean, and a great breakfast included.
Reviewed on Nov 7, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Clean hotel and the staff were very friendly l.
Reviewed on Nov 2, 2025

Wingate by Wyndham St. Louis/Fenton Route 66
Clean room, nice for a short stay
Reviewed on Nov 1, 2025

La Quinta Inn & Suites by Wyndham St Louis Route 66
Staff was great and the rooms were clean!
Reviewed on Nov 5, 2025

Best Western St. Louis Inn
Stayed 4 nights. Chose here because the price was great. The breakfast was ok, better some days then others. My room key had to be reset everyday which was absolutely annoying. Doors are thin so you can here a lot of noise. Housekeeping came everyday. Everything was a little old but clean for the ...
Reviewed on Nov 10, 2025
Hillsboro Hotel & Travel Guide\n
There are no Travelocity-accredited hotels in Hillsboro. Savvy travelers hoping to explore Hillsboro are best off booking one of the 18 rooms less than 19 miles (30 kilometers) away.
The Holiday Inn St. Louis West Six Flags, Missouri, which is the nearest accommodation, is situated 18 miles (29 kilometers) from the city center of Hillsboro. A secondary handy choice is the Hampton Inn & Suites St.Louis South at I-55, in Missouri, about 20 miles (32 kilometers) from the central area of Hillsboro.
The Comfort Inn Near Six Flags St. Louis is approximately 18 miles (30 kilometers) from the main part of Hillsboro. Another hotel is the Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, which is approximately 10 miles (16 kilometers) away. Some other alternatives around Hillsboro are the Holiday Inn St. Louis-South County Center and the Quality Inn Near Six Flags St. Louis.
The closest accommodation options in Farmington include Festus and Ironton. Festus is 10 miles (17 kilometers) to the east of Hillsboro, while Ironton is 45 miles (73 kilometers) to the east. Lodgings in Festus include the Lexington Inn - Shalimar Plaza & Conference Center and Comfort Inn. The Fort Davidson Hotel and Shepherd Mountain Inn are a selection of the Travelocity-registered hotels in Ironton.
If you are into sports and enjoy attending thrilling games make sure you spend a day at Busch Stadium, situated 35 miles (53 kilometers) to the northeast of Hillsboro. Wise travelers that like the convenience of booking accommodation in the neighborhood, reserve a room in the Four Seasons Hotel St Louis or Grand Center Inn.
Located 35 miles (57 kilometers) from central Hillsboro is Lambert-St. Louis International Airport. Stay nearby in Travelocity-listed accommodation at Marriott St. Louis Airport or Holiday Inn St. Louis-Airport.
Frequently asked questions
Recent Hillsboro hotel reviews by fellow wanderers

The Wildwood Hotel
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