Book Hotels in Hillsboro, MO
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Hillsboro hotels

Drury Inn & Suites Southwest St. Louis
This place does it right! I can't say enough good things about this place. The service was excellent! All employees, from check-in staff to maintenance, greeted us and asked if there was anything we needed anytime we were in close proximity. The room was very clean and comfortable. The management ...
Reviewed on Jan 19, 2026

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
Yes
Reviewed on Jan 15, 2026

The Wildwood Hotel
Room was clean and big with a separate sitting area. We would definitely stay there again .
Reviewed on Jan 21, 2026

River City Casino & Hotel
Excellent service. Excellent accommodations. Excellent food.
Reviewed on Jan 19, 2026

Holiday Inn Express & Suites St. Louis West - Fenton by IHG
Employees were great , room was comfortable
Reviewed on Jan 6, 2026

Best Western St. Louis-Kirkwood Route 66
Great place, near to everything. Hotel needs some upgrades, old rooms.
Reviewed on Jan 15, 2026

Best Western St. Louis Inn
The room was very clean we stayed two nights and the housekeeping was excellent.. everyone we delt with was extremely friendly and helpful.
Reviewed on Jan 20, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Best possible value for the money. I'd have paid 50% more and been satisfied.
Reviewed on Jan 17, 2026

Wingate by Wyndham St. Louis/Fenton Route 66
I would stay again at this hotel. Friendly, easy to deal with and very accommodating
Reviewed on Jan 12, 2026
Hillsboro Hotel & Travel Guide\n
There are no Travelocity-accredited hotels in Hillsboro. Savvy travelers hoping to explore Hillsboro are best off booking one of the 18 rooms less than 19 miles (30 kilometers) away.
The Holiday Inn St. Louis West Six Flags, Missouri, which is the nearest accommodation, is situated 18 miles (29 kilometers) from the city center of Hillsboro. A secondary handy choice is the Hampton Inn & Suites St.Louis South at I-55, in Missouri, about 20 miles (32 kilometers) from the central area of Hillsboro.
The Comfort Inn Near Six Flags St. Louis is approximately 18 miles (30 kilometers) from the main part of Hillsboro. Another hotel is the Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, which is approximately 10 miles (16 kilometers) away. Some other alternatives around Hillsboro are the Holiday Inn St. Louis-South County Center and the Quality Inn Near Six Flags St. Louis.
The closest accommodation options in Farmington include Festus and Ironton. Festus is 10 miles (17 kilometers) to the east of Hillsboro, while Ironton is 45 miles (73 kilometers) to the east. Lodgings in Festus include the Lexington Inn - Shalimar Plaza & Conference Center and Comfort Inn. The Fort Davidson Hotel and Shepherd Mountain Inn are a selection of the Travelocity-registered hotels in Ironton.
If you are into sports and enjoy attending thrilling games make sure you spend a day at Busch Stadium, situated 35 miles (53 kilometers) to the northeast of Hillsboro. Wise travelers that like the convenience of booking accommodation in the neighborhood, reserve a room in the Four Seasons Hotel St Louis or Grand Center Inn.
Located 35 miles (57 kilometers) from central Hillsboro is Lambert-St. Louis International Airport. Stay nearby in Travelocity-listed accommodation at Marriott St. Louis Airport or Holiday Inn St. Louis-Airport.
Frequently asked questions
Recent Hillsboro hotel reviews by fellow wanderers

The Wildwood Hotel
Explore More Ways to Travel with Travelocity
- Cadet Hotels
- Imperial Hotels
- 3 Star Hotels in Dittmer
- 5 Star Hotels in Dittmer
- Apartments in Dittmer
- Extended Stay Hotels in Dittmer
- Dittmer Hotels
- Motels in Dittmer
- Vacation Homes in Dittmer
- Tiff Hotels
- Pacific Hotels
- Hotels near Robertsville State Park
- Apartments in Barnhart
- B&B in Barnhart
- Cabins in Barnhart
- Cottages in Barnhart
- Extended Stay Hotels in Barnhart
- Barnhart Hotels
- Villas in Barnhart
- Hotels near St. Francois State Park
- Tesson Ferry Hotels
- Apartments in Pevely
- B&B in Pevely
- Cabins in Pevely
- Chalets in Pevely
- Extended Stay Hotels in Pevely
- Convention Center Hotels in Pevely
- Hotels with Hot Tubs in Pevely
- Luxury Hotels in Pevely
- Pevely Hotels
- Motels in Pevely
- Vacation Homes in Pevely
- Villas in Pevely
- Arnold Hotels
- Hotels near Swing-A-Round Fun Town
- House Springs Hotels
- Hotels near Six Flags St. Louis
- Scotsdale Hotels
- Hotels near Suson Park
- Hotels near Hurricane Harbor
- Hotels near Spooner's Frozen Custard
- Hotels near Washington State Park
- 3 Star Hotels in Festus
- Farmstay in Festus
- Apartments in Festus
- B&B in Festus
- Cabins in Festus
- Condos in Festus
- Extended Stay Hotels in Festus
- Guest Houses in Festus
- Cheap Hotels in Festus
- Kid Friendly Hotels in Festus
- Hotels with Bar in Festus
- Hotels with an Indoor Pool in Festus
- Pet Friendly Hotels in Festus
- Hotels with Shopping in Festus
- Festus Hotels
- Inns in Festus
- Motels in Festus
- Rv Parks in Festus
- Villas in Festus
- Eureka Hotels
- Hotels near Myron and Sonya Glassberg Family Conservation Area
- Lodges in Crystal City
- Vacation Homes in Crystal City
- Hotels near Route 66 State Park
- Hotels near Lone Elk Park
- Hematite Hotels
- Farmstay in Herculaneum
- B&B in Herculaneum
- Cabins in Herculaneum
- Herculaneum Hotels
- Motels in Herculaneum
- Apartments in De Soto
- B&B in De Soto
- Cabins in De Soto
- Extended Stay Hotels in De Soto
- Casino Resorts & in De Soto
- Golf Resorts & in De Soto
- Pet Friendly Hotels in De Soto
- Ski Resorts and in De Soto
- Spa Resorts & in De Soto
- De Soto Hotels
- Motels in De Soto
- Vacation Homes in De Soto
- Resorts in De Soto
- Hotels near Wyman Center
- Fenton Hotels
- Hotels near Winding Brook Estates Lavender Farm






